MDPV - So how dangerous is it?

[Deleted member 175441]

Ive been doing quite a bit of this stuff quite recklessly for like 11 days now, taking a day break between most binges. I don't have a scale so ig I don't really know how much I'm doing, but its really compulsive and its made me panic more than any other drug I've done. It doesn't really make me feel like shit the day after or when I come down, but it does get my heart rate pretty high.

My favourite part about it is that I get INTENSE dreams afterwards and can fall asleep pretty easily. It's easy for me to get overstimulated tho and still want more :/, and it never was that euphoric for me either... although It effects dopamine to where I want to do it like it was :D

Edit: I guess idk if ive been doing it recklessly because I'm not sure of the doses I've been doing untill I can find a mg scale. It's going to be a suprise as to wether I've been doing rediculous amount or if my 10 little half inch lines a binge have been jus abount right :/

 

[tamtoot]

I have used mdpv 6 times in last year, always binged like hell on 1 gram until it is gone. Last time i got bad pain in my stomach that didn't disappeared, so I visited my doc and found peptic ulcer. I had an history of gastroenterological disease but never so bad, so I think it was catalysed by peevee.
Be safe, eat frequently and do not binge on PV.
I could also say that I was living like a bum for a year or two, binging on a different stimulants(mainly amphetamine and alpha-ppp) and for overall 10 years had a bad nutrition(right now I'm living good and eat good vegeterian food, but 3 or 4 years ago - oh God, I was eating in fast food) so alone MDPV is not gonna make you ill, but it can seriously speed up the disease.

 

[tamtoot]

Strange thing that amphetamine has a protective effect on gastric ulceration
http://www.wjgnet.com/1007-9327/12/7168.pdf

I imagine it is absence of food for a prolonged period of time(24 hours) made me ill.

 

[Dedbeet]

Not that bad

Other than being very compulsive for most, I don't think it's an especially dangerous stim. Probably no more so than pyrovalerone itself, which is schedule V in the U.S. (least 'dangerous' of the scheduled compounds, and I don't believe is neurotoxic).

Overdoing it is highly unpleasant, but apparently not so dangerous -- a good thing, compared to subbies that just keep increasing euphoria the more you do of it.

Seems to have relatively little vasoconstrictive and other effects on the heart, and not primarily adrenergic like DMAA.

Doesn't have a "low therapeutic index" like diphenyl prolinol (which gets you high at about the point it makes you psychotic, IME).

Not nearly as a paranoia-inducing as desoxypipradrol, nor as long acting. Yet, not very short-acting either, and so not "crazy level" compulsive.

Quite honestly, if someone was dead set on experimenting with 'pure stims', dopaminergic substances, and such -- MDPV would be the first I'd point them to. Although I wouldn't point anyone to anything like that... but ya know what I mean ;-).

 

[Dedbeet]

I was thinking about starting a new thread for this but then I found this thread.

I'm new to MDPV and I was wondering what you guys would consider responsible use vs abuse.

For one, be aware right from the start that it's compulsive -- and don't re-dose unless you're *willing to* lose control. Seriously. Don't ever pretend "it can't happen to me", because it can and it will.

Take a step back before even trying it, and keep "standing back from it" when using it, if you don't want usage to become compulsive.

Not that compulsive use is necessarily irresponsible, if you don't mind being 'taken over' by the drug. I get the sense some people complain about this endlessly, while secretly loving it.

 

[killermunchies]

For one, be aware right from the start that it's compulsive -- and don't re-dose unless you're *willing to* lose control. Seriously. Don't ever pretend "it can't happen to me", because it can and it will.

Take a step back before even trying it, and keep "standing back from it" when using it, if you don't want usage to become compulsive.

Not that compulsive use is necessarily irresponsible, if you don't mind being 'taken over' by the drug. I get the sense some people complain about this endlessly, while secretly loving it.

I took a day off from it but did it again today while hanging out with some friends in a social setting. It was by far the worst experience I had with it. I definitely took too much, and after an hour of feeling pretty good, the jaw clenching got very annoying and uncomfortable. Then the come down came, which brought another 3 hours of shit. Redosing wasn't the problem though. I got greedy when making the lines up and added a little more than usual. After my jaw started going mad, redosing was the last thing on my mind. I'm gonna take a few days off from it and try it again with a more conservative dosage. Definitely not the best drug out there, but I haven't given up on it yet. Although from what I've read, a lot of people like it at first but it turns ugly pretty quick. Only one way to find out...

I feel like the key to MDPV, at least in my short experience with it, is not to try to get too much out of it. The optimal dose for me feels pleasant, but that's as good as it gets before it turns bad. Kind of like alcohol when you get to the point where one more shot is only going to make things worse. In low doses of MDPV with out redosing, the euphoria and the come down are both fairly mild, but it's still a positive experience. In higher doses, there's a bit more euphoria at first, but then the negative effects overpower the positive ones.

 

[Dedbeet]

I feel like the key to MDPV, at least in my short experience with it, is not to try to get too much out of it. The optimal dose for me feels pleasant, but that's as good as it gets before it turns bad. Kind of like alcohol when you get to the point where one more shot is only going to make things worse. In low doses of MDPV with out redosing, the euphoria and the come down are both fairly mild, but it's still a positive experience. In higher doses, there's a bit more euphoria at first, but then the negative effects overpower the positive ones.

Definitely agree about the higher doses.

Low, frequent and repeated re-dosing can get really interesting with this substance, IMO (rather than dosing once moderately/high and then waiting a long time). But the risk with that, of course, is becoming its b*tch.

 

[Jabberwocky]

how bad is mdpv for you? i know the 'bath salts' are typically mdpv with fillers, i'm sure the fillers are nothing more than coke fillers...but has mdpv had any studies showing it's any worse than other similar drugs

 

[killermunchies]

how bad is mdpv for you? i know the 'bath salts' are typically mdpv with fillers, i'm sure the fillers are nothing more than coke fillers...but has mdpv had any studies showing it's any worse than other similar drugs

It is actually a fairly safe drug in terms of the risk of causing actual damage to the body. I don't have any studies for you but that seems to be the general consensus of what I've read about it. Just because it won't destroy your brain doesn't mean that it can't make your life into a train wreck though. It is very fiendish and can easily lead to compulsive use. It can also make you feel like absolute shit if you take a little too much.

 

[Jabberwocky]

okay so overall if used responsibly and moderatly and no long binges it's no worse than meth/speed/coke/other stims

 

[ektamine]

okay so overall if used responsibly and moderatly and no long binges it's no worse than meth/speed/coke/other stims

huh? if used responsibly, or even irresponsibly but without binging, or even if you you do end up binging, its still a HELL of a lot safer and better for you than applying the same usage pattern to meth/speed/coke. MDPV is the most physically benign stimulant I've ever (ab)used. And thats saying alot.

MDMA has done my body and brain much, much more harm then MDPV.
Same with methamphetamine, amphetamine, and cocaine.

The worst MDPV has given me is temporary psychological hell / psychosis only lasting until I put the damn bag down.

Just because it won't destroy your brain doesn't mean that it can't make your life into a train wreck though. It is very fiendish and can easily lead to compulsive use.

This is also good advice to keep in mind when considering / using MDPV.

 

[leiphos]

I searched BL but couldn't find a decent answer. When vaporizing MDPV (non freebase) in a crack pipe (long glass stem with bulb), what type of leftover residue should be expected? Specifically, what color? My experiences were inconclusive: I encountered beige, light yellow, dark brown, sludgey black - often several colors gradated. What does residue look like in other people's pipes? Any notable links concerning this? Any pictures?

Also - sometimes while I'm smoking, unburned MDPV ends up atop the dark residue; I'm curious if it's especially dangerous to burn this powder and thus inhale (potentially) the vapors from the residue underneath.

I'm also wondering if the presence of residues in the first place is a bad sign. Obviously I know smoking MDPV is harmful, but I want to minimize my risk, as well as understand it. The harm reduction philosophy behind BL is why I posted this question here.

 

[vortex30]

huh? if used responsibly, or even irresponsibly but without binging, or even if you you do end up binging, its still a HELL of a lot safer and better for you than applying the same usage pattern to meth/speed/coke. MDPV is the most physically benign stimulant I've ever (ab)used. And thats saying alot.

MDMA has done my body and brain much, much more harm then MDPV.
Same with methamphetamine, amphetamine, and cocaine.

The worst MDPV has given me is temporary psychological hell / psychosis only lasting until I put the damn bag down.

This is purely subjective evidence. MDPV gives me terrible side effects. Heart pain, kidney pain, very long lasting insomnia and peripheral stimulation. MDMA has never done me any harm that is comparable to MDPV or Mephedrone. Amphetamine has never caused me a single painful physical side effect. Cocaine, same story. Personally I'd say one is better off not abusing any stimulant, but if I had to choose one to use in any capacity, it would NOT be MDPV. Probably would be amphetamine.

 

[Dedbeet]

The worst MDPV has given me is temporary psychological hell / psychosis only lasting until I put the damn bag down.

Ditto here, although sleep deprivation can add considerably to peevee's negative effects.

Also, IME, doing too much too fast can be problematic -- even if there's no severe anxiety involved, dopamine can be over-tweaked, resulting in a sudden/mild psychosis. IMO, vaping/smoking it carries this risk.

"Pounding" any substance for long periods is asking for trouble, of course, and peevee is no exception. One can't blame that one on the substance at all, only on the idiocy of its user.

 

[captain codshit]

I'm finding this pure white stuff isn't particularly sketchy at all compared to usual. Also chasing it seems even less so. Rids that anxious feeling you get before it's fully hit sniffing.

Started off at 10mg but it's pretty hard to vape any less than 20mgs to not obliterate it all with the heat.

What's the general consensus with regard to chasing or best ROA for PV? I'm finding the pure hcl much less fiendish than stuff I've previously binged on. I've been sniffing for 4 days but only 5mg every few hours. Decided to vape some today, started with 10mg. Now I think I've had about 40mg total.

Also is dosing with GBL likely to cause any problems I should be aware of?

Also has anyone in ADD had any sucess with the stuffmonger conversion to tan? As far as I can gather the tan is mostly waffle & nostalgia but the belief of some people from here that it works make me thing I should have another bash..

 

[literate]

Gamma-butyrolactone is hard on the liver; methylenedioxyphenylpyrovalerone, on the kidneys.

 

[ektamine]

This is purely subjective evidence. MDPV gives me terrible side effects. Heart pain, kidney pain, very long lasting insomnia and peripheral stimulation. MDMA has never done me any harm that is comparable to MDPV or Mephedrone. Amphetamine has never caused me a single painful physical side effect. Cocaine, same story. Personally I'd say one is better off not abusing any stimulant, but if I had to choose one to use in any capacity, it would NOT be MDPV. Probably would be amphetamine.

Huh.. I agree, its subjective evidence. Thats all we have on RC's. There are no toxicity / neurotoxicity studies on MDPV. The evidence is purely anecdotal, as far as I can gather. With that being said, I think your accounts of MDMA never doing you harm comparable to MDPV is purely subjective as well. I have hellishly abused both MDMA and MDPV, although in very different fashions and at very different times in my life. MDMA abuse, after doing it over and over and over again often spaced way too close together and in over-excessive doses, gave me serious problems in my cognition, memory, focus, mood, etc. All of these have recovered almost completely now that its been over a year. The 'fog' this abuse created lingered for a loooong time after I stopped this abuse.

My abuse of MDPV, comparatively, was worlds worse than my abuse of MDMA. But the lasting effects were not. Excessive binge after excessive binge after excessive binge. And generally within a week after stopping all use, I would feel very close to where I started off, i.e. fine.

I have found that many others seasoned users of PV have similar views on its toxicity / risks.

 

[Transform]

Gamma-butyrolactone is hard on the liver

It's converted in the blood. I seem to remember there was a consensus that GHB is not hard on the liver.
There is no evidence to back your claims about MDPV either.

 

[ebola?]

There are no toxicity / neurotoxicity studies on MDPV.

Actually, because it was developed as a potential stimulant for medical use (along with several other subsituted pyruvalerones), we do have some toxicity data on mdpv. Namely, it has a very high therapeutic index, which is lucky, 'cause people binge like hell on it. I couldn't find any data on receptor binding, nor anything definitive on in-vivo metabolism.

ebola

 

[ektamine]

Gamma-butyrolactone is hard on the liver; methylenedioxyphenylpyrovalerone, on the kidneys.

Do you have any source(s) to back this up? Or is it just based off the often reported kidney pain that can follow excessive abuse?

I've found that I don't get any kidney pain if I take care of my self (eat good / hydrate good / sleep good / exercise good) before during and after (ab)using MDPV.

There are no toxicity / neurotoxicity studies on MDPV.

Actually, because it was developed as a potential stimulant for medical use (along with several other subsituted pyruvalerones), we do have some toxicity data on mdpv. Namely, it has a very high therapeutic index, which is lucky, 'cause people binge like hell on it. I couldn't find any data on receptor binding, nor anything definitive on in-vivo metabolism.

ebola

Ah, I stand corrected. Thanks! Does anyone have links to any studies or publications regarding this data? In the meantime, a-googling-I-will-go