• N&PD Moderators: Skorpio | someguyontheinternet

mephedrone long term negative effects progress reports

hey read this

Well,
I am one of those morons who didn't do any real research, as there really is no long term information about mephedrone. Needless to say, since April of this year I have done 150 grams of mephedrone. That's 150 divided by roughly 180 days. I have stopped doing it for almost a month now. The first three days I got KILLER brain zaps and felt as if I was really tired. After two weeks I was pretty much fine. And today a month later, I don't feel any different and have recently got a physical and have checked out 100 percent fine. The lady even went on to say that my blood pressure was great and my standing pulse rate was perfect. I AM NOT ADVOCATING mephedrone use in any way. It is a nasty gross drug. It is addicting as fuck, and it messes with you big time. Strangely, I have felt no depression whatsoever. Kindly drop in with your 2 cents as to what you think of this...
FUSIONZ
 
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Was using about half a gram every weekend from Jan-April.

Stopped after the ban.

I now have short-term memory problems. Example:

I go into my room from the kitchen to get something, by the time I get to my room (5 seconds later) I've forgotten why I went in there. I then have to think really hard to remember what I went in there for.

I am 28 and otherwise healthy, had no such memory problems prior to starting to use meph
 
its a rough ass drug but since not having had a binge since jan 8months later (minus one 250mg bomb in may) i notice no side effects.

a nasty drug we can do without
 
I had the peripheral hypoxia symptoms (what is mostly being referred to as vasoconstriction here, but I have seen theories in other threads suggesting another process could be involved, perhaps in combination with vasoconstriction). This was about 16 hours into a binge of 1.5 grams, mostly insufflated, of a white, pure-looking powder (not saying it was pure, just distinguishing it from the yellowish-looking stuff that has been referenced). My feet started to change color towards gray-ish blue, I then began to experience some tingling and then numbness in the feet. 20 minutes or so later this spread to my fingers and to a lesser extent hands.

This symptoms were somewhat subtle when they began, although they got bad enough within 20 minutes that it would have been hard not to notice. Because I had been reading up and was on the lookout for this, I immediately stopped redosing, drank a couple cups of water, and had an aspirin (thinking was to thin the blood and enhance circulation--just a hunch, I have no scientific basis for thinking it would help). I found that changing positions frequently seemed to enhance the circulation. The symtpoms peaked around 1 hour after the last dose I had insufflated, and resolved entirely within a couple hours. BUT TO ANYONE THINKING ABOUT GOING ON A MEPH BINGE -- JUST BECAUSE I WAS LUCKY, DON'T ASSUME YOU WILL BE.

I went to bed, felt fine the next day except for a general hangover not dissimilar from other stim binges I have been on. Several days later now, I have no lingering symptoms.

I may have dodged a bullet, and thanks to everyone who has been posting information on this. I do not endorse going on a binge like I did, but if one finds themselves in that situation, be on the lookout for this known and poorly-understood side effect, and STOP DOSING if you get symtpoms. The drug definately compels one to do more, but the risk of having one's extremeties die of lack of oxygen while still attached to their body should be a deterrent...
 
Is it possible to avoid these effects by using vaso-expanding drugs?
 
Is it possible to avoid these effects by using vaso-expanding drugs?

Probably however the fact that effects persist for months indicates there's more at work than just simple vasoconstriction.
 
Probably however the fact that effects persist for months indicates there's more at work than just simple vasoconstriction.
Could this be due to hormonal changes or toxicity to certain types of receptors?
 
9 months into my mephedrone taking career and not one negative report. I've binged on it, mixed it, not one blue toe or knee. Clean bill of health as I have to go to the doctor for checkups as I am a "researcher" and by simply not sitting still for 4 hours you can avoid many of the problems. Progress report is not one bad thing.........I even go on a jog the day after for god's sake.
 
Can someone (and I know this will be difficult, if not impossible) compare the danger level of using (or abusing) this versus a more common drug? i.e. should it be treated like mdma and no more than once a month? or is it so much worse that it should be avoided at all costs?
 
^^^It has a cardio-toxic metabolite that can mess with your heart valves, but a drug like MDMA more than likely is neuro-toxic(so many studies, so many results) so it is hard to compare. Most people encounter problems, and we don't know the long term effects other than what I mentioned above. I take an aspirin before dosing, and never sit in one spot too long, hence I haven't had any v.c. problems...no blue limbs, or even red hands.
 
I take an aspirin before dosing, and never sit in one spot too long, hence I haven't had any v.c. problems...no blue limbs, or even red hands.

Or it could just be that you're lucky (although you gave good advice).

ebola
 
nevertheless aspirin is a very good choice


it can only be beneficial

The only time i got serious chest pains on meph was when I combined it with Adderall aka amphetamine salts (very bad idea btw, I have combo'd addies with MDMA and/or meth many times and it was never scary like adderall and meph). I took a 350mg aspirin and the pains subsided.

It can literally save your life, but seeing a doc is probably advisable when you start getting chest pains...:\

Cheers,
-SSS
 
has anyone had any positive effects using ginkgo biloba during or after a binge? it is supposed to be a vasodilator i think...
 
Anything as powerful as Mephedrone is unlikely to be countered by anything but a strong vasodilator.
 
Hmm, your probably right. Still, it is also a mild anticoagulant, maybe that's worth thinking about... still... I found these earlier. Might be of a vague relevance for people willing to try anything to help side effects...

http://www.ncbi.nlm.nih.gov/pubmed/17564952

http://www.ncbi.nlm.nih.gov/pubmed/16451753

The second one seems more interesting. "The results suggested that Ginkgo enhanced endothelium-dependent vasodilation and elevation of the endothelial intracellular Ca(2+) level in SHR, resulting in hypotension."
 
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