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  • BDD Moderators: Keif’ Richards

Poly drug use and cycling to minimize dependency & tolerance risk - In other words this idiot's addicted to being high

placebonaut said:
nac as in the nootropic? does that effect nicotine???
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Maybe he means Nicotinamide (Niacinamide). People always mix it up with Niacin cause both are vitamin B3, but they’re not the same thing.

Niacin is the one that gives the flush, hot face, red skin etc.
Niacinamide is basically the non flush version.

Some people say Niacinamide kinda kills the nicotine buzz a bit and can help with cravings too.

NAC is something completely different though. It’s not even vitamin B3. NAC is more like an amino acid type supplement.

What NAC mainly does is help your body make more glutathione, which is one of the main antioxidants your body uses for detox and protection. That’s why people mostly use NAC for liver support, recovery, oxidative stress, addictions/cravings and stuff like that.

So basically:

Niacin = flushing B3
Niacinamide = non flush B3
NAC = glutathione booster / antioxidant / liver support

Names sound similar but completely different mechanisms.
 
My only question is, where TF do you safely source all of this stuff? All I’ve got access to is what I can get prescribed. How do you find stuff that isn’t laced with Fentanyl and that won’t kill you?
 
placebonaut said:
nac as in the nootropic? does that effect nicotine???
Click to expand...
Self- experiment today: 600 mg NAC (N-Acetylcystein = ACC) don't kill the buzz.
lostsoulforgood said:
My only question is, where TF do you safely source all of this stuff? All I’ve got access to is what I can get prescribed. How do you find stuff that isn’t laced with Fentanyl and that won’t kill you?
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If you mean the supplements like NAC or Agmatine, you can get those OTC
Edit: Agmatine isn't OTC here, but can be legally ordered via Internet.

Random experience of mine: If you smoke or vape Nicotine and you kinda feel it hurting your lungs, try to get an Asthma spray containing cortisone. It helps to slow down the inflammation. At least for me that helps notably.
 
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cnnka said:
Maybe he means Nicotinamide (Niacinamide). People always mix it up with Niacin cause both are vitamin B3, but they’re not the same thing.

Niacin is the one that gives the flush, hot face, red skin etc.
Niacinamide is basically the non flush version.

Some people say Niacinamide kinda kills the nicotine buzz a bit and can help with cravings too.

NAC is something completely different though. It’s not even vitamin B3. NAC is more like an amino acid type supplement.

What NAC mainly does is help your body make more glutathione, which is one of the main antioxidants your body uses for detox and protection. That’s why people mostly use NAC for liver support, recovery, oxidative stress, addictions/cravings and stuff like that.

So basically:

Niacin = flushing B3
Niacinamide = non flush B3
NAC = glutathione booster / antioxidant / liver support

Names sound similar but completely different mechanisms.
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thanks for taking the time to write that out, very helpful!

Mushoku_Sensei said:
Self- experiment today: 600 mg NAC (N-Acetylcystein = ACC) don't kill the buzz.
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I thought it was a bit of a weird statement, thanks for confirming
 
Mushoku_Sensei said:
Self- experiment today: 600 mg NAC (N-Acetylcystein = ACC) don't kill the buzz.

If you mean the supplements like NAC or Agmatine, you can get those OTC
Edit: Agmatine isn't OTC here, but can be legally ordered via Internet.

Random experience of mine: If you smoke or vape Nicotine and you kinda feel it hurting your lungs, try to get an Asthma spray containing cortisone. It helps to slow down the inflammation. At least for me that helps notably.
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Or maybe stop vaping? Just a thought.
 
BadBoy377 said:
Or maybe stop vaping? Just a thought.
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just vaping cannabis 2-3 times a week for me has me coughing and spluttering, makes my chest sore, I fucking hate it.

edibles just aren't as good sadly, have even tried making my own and tinctures but it's too much of a ball ache
 
BadBoy377 said:
Or maybe stop vaping? Just a thought.
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Yeah, that's the ultimate solution.... My kids can't wait for that to happen. But for now I'm busy keeping the harder stuff low 😜
placebonaut said:
just vaping cannabis 2-3 times a week for me has me coughing and spluttering, makes my chest sore, I fucking hate it.
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Felt. Weed is much worse than Nicotine in that.
placebonaut said:
edibles just aren't as good sadly, have even tried making my own and tinctures but it's too much of a ball ache
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Coming from a country where you can't get them legally I understand the trouble. Even if I wasn't too lazy I can hardly make the kitchen/house smell that much...
 
Mushoku_Sensei said:
Self- experiment today: 600 mg NAC (N-Acetylcystein = ACC) don't kill the buzz.

If you mean the supplements like NAC or Agmatine, you can get those OTC
Edit: Agmatine isn't OTC here, but can be legally ordered via Internet.

Random experience of mine: If you smoke or vape Nicotine and you kinda feel it hurting your lungs, try to get an Asthma spray containing cortisone. It helps to slow down the inflammation. At least for me that helps notably.
Click to expand...
I meant all the drugs in OPs initial post.
 
cnnka said:
NAC = glutathione booster / antioxidant / liver support
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I meant this btw. Not Niacin. And ya it appears to severely blunt dopamine related buzzs, euphoria from substances etc. but it did pull me out of a mess Wednesday. I still cannot feel my coffee and nicotine and its like 24 hours later. kinda sad
 
placebonaut said:
just vaping cannabis 2-3 times a week for me has me coughing and spluttering, makes my chest sore, I fucking hate it.

edibles just aren't as good sadly, have even tried making my own and tinctures but it's too much of a ball ache
Click to expand...

Mushoku_Sensei said:
Felt. Weed is much worse than Nicotine in that.
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I've never been a tobacco/nicotine user but have noticed in the 2 1/2 since I quit marijuana(was mainly dabbing) that I stopped getting severe chest pains. The main source of my pains was from arthritic and neurological issues I have; but the smoking seemed to exacerbate it.
 
another bit of an update from me.

so pregab tolerance has again sky rocketed, going on another break, last time it was 1 month, I'm going to go for longer this time, however having read about things the other GABA drugs I take is clearly contributing to pregab tolerance - started at 300mg and now 600-900mg always combined with diazapam which has moved from 10mg up to 30mg, thankfully I've restrained this combo to just once per week so don't feel like it's out of hand just yet BUT clear sign that I need to stop.

I've been hitting Soma way too hard, what has been 1000mg every 2-3 days has more recently become 2000-3000mg, this has got to a point where I'm getting mild rebound anxiety the day after a binge - thank fuck it's mild rebound anxiety, I'm able to tough it out with a few nootropics.

I've got to admit that it's scared me, fuck only knows how bad benzo withdrawal must be but I have no desire to fucking find out.

So I'm actively now reducing my soma usage as well, max dose will be 1000mg in 1 sitting and no more coupled with 10mg diaz, I'm going to move this to 3-4 days between uses with a view to it becoming once per week and then once per fortnight.

Alcohol is a problem again and I need to stop drinking - my plan is exercise because the more I exercise the less I want to drink, I'm currently exercising almost daily, mainly a walk, but the odd run, and for the 1st time in a long time I went out on my bike in the sunshine, it was bloody glorious, really made me feel good.

I'm using cannabis daily and suspect it might be contributing to anxiety too.

The background to all this is a lot of personal & heavy emotional shit, stress and anxiety. Right now I'm pretty much sat in a room just coping with life, trying to come to terms with a lot of stuff, on the right side of a mental breakdown but space I'm able to give myself is just what I need to sort my head out, again I'm lucky it's the right side because if it were a bit further the other way then I'd be doing a lot more drugs than I currently am. I'm also so very lucky that I have a close and very supportive family around me, lots of people don't have this, without it I'd be screwed.

1 big bit of advice I would like to put out there that's really helping me understand things - I keep a log of everything I take, amounts, notes, issues etc, it allows me a realistic and honest view of what is really going on, especially dosage and frequency, no where to hide from yourself this way.

I've stayed off coke, GBL, phenibut, and Xanax for over a month, 2 months for some, and have reduce ketamine & methedrone usage down recently as well.

major goal here is to become a weekend warrior, though I've very much considered the "fuck it" route and giving myself over to the chaos as well.

Thought I would add in a relevant quote from @BadBoy377 from another thread which pretty much nails things on the head, thanks @BadBoy377 just the advice I needed and know you're trying to look out for me when you say what you do :love:

BadBoy377 said:
You and me both, mate.

I did the same, like somehow slowly alternating substances will allow us to escape unscathed from the long term effects of regular substance use. Definitely won't leave a frayed rubber band of emotions where the cracks show when you stretch it too far from pulling in all different directions at once... Will it?

I read about this years ago. On here. From another user doing exactly the same thing. They termed it "The Superhabit" where eventually you just end up with ill effects from everything you've been using. Generally it's just a case of put it all down, slowly, bit by bit. Then see where you are, take stock and move on with your life. Or just fuck everything up big style with extra helpings of mental and possibly physical pain/discomfort.

Been there can confirm it's no fun.

Start with the booze and things will get easier and you'll feel better.

All the best.
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Why am I posting this? to share the reality.

I don't think I'm in too deep yet, but I'm teetering on the edge of what could be a pretty destructive path, I can see it, I'm aware, I know the risk and the consequences, people keep telling me & warning me, yet none of that is enough to stop me.

the old phrase "fuck around and find out" springs to mind - listen to the warning signs placebonaut you dumb fuck
 
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Mushoku_Sensei said:
Mind explaining what Legacy opi pca means?
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of course butterfly..

Legacy opioid patients" are individuals maintained on long-term, often high-dose, opioid therapy for chronic non-cancer pain, initiated by previous clinicians prior to current stringent guidelines. Managing their care requires balancing strict safety protocols with the medical risks of abrupt withdrawal.

The Tapering Dilemma: Current CDC guidelines advise against initiating high-dose, long-term opioids, but forced or rapid tapers for legacy patients can lead to severe withdrawal, uncontrolled pain, and patients turning to illicit opioids

Pain vs. Harm: Prolonged opioid use can cause opioid-induced hyperalgesia (increased pain sensitivity) and negative physiological impacts, complicating ongoing treatment.
>>>>>> OIH = a big fucking lie. Stop the Oxycodone, Methadone and this race car will come to a complete HALT.

PCA = Patient Controlled Analgesia // this is typically used in hospital session where the patient is dictating how much and when to keep them comfortable. I am treated in-patient & out-patient the same way. The in-patient, I have to do a "gentleman's agreement" with the doctor first these days, " Geez doctor you have been throwing all fast-balls and I have't slept in 3-4 days." Sounds like it is time for the to take over.\ lol lol...

Butterfly, I have a formal doctor's note that says to call him directly and that I am under his care, wherever, I go. Call his cell phone number...."
 
Polypharmacy is the concurrent use of multiple medications by a single patient, typically defined as 5 or more medications daily. It is common among older adults and individuals with multiple chronic conditions.

I have to get back to work on my race car. I will explainit later. have a good day butterfly
 
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