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Been gifted a authentic and wedinos tested Quualude from 1970s. What dose?

Sorry - the oxygen which has two lone-pairs. They can act as hydrogen-bond acceptors so MAY increase the melting point.

I just responded to you commenting that the 2-methoxy homologue was likely to be similar to etaqualone and was commenting on my single taste of that compound.

As I said, the hilariously wrong Wikipedia page on nitromethaqualone shows that same 2-methoxy which is, I suspect, what get the vendor the idea.

But in almost every case, anything bigger than that 2-methyl reduces sedative activity. Shetty patented the 2-trifluoromethyl homologue as an antispasmodic so I assume that was an attempt to separate the two activities.

As I said, they tested hundreds of related compounds so if the figured out that substituting the 2-position vastly increased activity and rational design would dictate testing a range of 2 substituents but for whatever reasons, they chose the 2-methyl.
 
4DQSAR said:
Sorry - the oxygen which has two lone-pairs. They can act as hydrogen-bond acceptors so MAY increase the melting point.

I just responded to you commenting that the 2-methoxy homologue was likely to be similar to etaqualone and was commenting on my single taste of that compound.

As I said, the hilariously wrong Wikipedia page on nitromethaqualone shows that same 2-methoxy which is, I suspect, what get the vendor the idea.

But in almost every case, anything bigger than that 2-methyl reduces sedative activity. Shetty patented the 2-trifluoromethyl homologue as an antispasmodic so I assume that was an attempt to separate the two activities.

As I said, they tested hundreds of related compounds so if the figured out that substituting the 2-position vastly increased activity and rational design would dictate testing a range of 2 substituents but for whatever reasons, they chose the 2-methyl.
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Before diving in head first, I think it would be a good idea to pick your brains for your knowledge and ask if you can see any potential alarm bells with these 2-Methoxyqualone pills?

According to user reports seen on other platforms this substance is more potent or bioavailable than etaqualone, and seems to be scoring much higher for subjective euphoric effects with people feeling both safe and fine and dandy with one of the 330 mg tablets, taken with an oral dose..(There are no reports of anyone finding that oral dose too much.)

Much more like the OG methaqualone in that regard, especially with all the problems with oral dosing of etaqualone, with the window for recreational effects being very narrow, and close to the lethal o/d dose range, according to the main vendor who sold it in the UK back in the day. They were the biggest and most esteemed UK RC vendor back in the day. I think you said you knew them, IIRC.

I cant get any confirmation from anyone about sublingual dosing offering better bio-avilability, as was the case with etaqualone. It seems I may be the first person to post about that ROA, with this substance.

It's still very new, and there's very little info about it so far. The first reports seen on Wedinos appeared in December 2025, and there was quite a few. It seems that was it's 'launch date.'

I'll probably just take the first pill orally, as others have already confirmed that its safe and it works just fine that way. I suspect s/l will be stronger though, but I would imagine taking half a 330mg tablet, and using the 'wait and see' approach should be safe enough.
 
It's available from a couple of vendors on one of the relatively newer market places, that is not the dark web.

Their group chat is pretty fucking low level. Some meth head individual went full attack mode on me, just for asking the sort of questions I've been asking on BL.

Apparently I was 'pretending to know what I was talking about' and I think that was what upset the guy about my posts.

Exhibiting any knowledge or experience or attempting any intelligent discussion was not welcome. I suspect that guy was just a fucking royal arsehole tbh. Other people were OK and helpful, but a couple of absolutely moronic level posters, making the chat feel unwelcoming. He was extremely scathing about me asking questions first, rather than jumping straight in with both feet with no prior knowledge, and just trying what works for me. :sus: He was one of a few meth heads on there. and I guess if they're into meth they're probably going to be a bit more reckless and completely alien to the more measured and informed HR type of approach that members on the likes of BL or even Reddit tend to have.

On the whole, I think that's why we're still alive, and not diving headlong into using things like meth, without even asking any questions first, or learning anything about the way it affects your mind and body.
 
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I'm out of touch with 'newer markets', sadly.

But there's still no reliable record of the stuff actually being good, outside of there being a market in Inner Mongolia. For four years, which would make me wonder why it hasn't taken off yet.

You'd expect the Chinese (great bunch of lads) to have pushed it elsewhere before now. They supply South Africa with actual methaqualone after all.
 
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It's been a very steep learning curve for me. But I'm brand new on there since the last couple of weeks.

There is a dark web level of products available, but it's been easier to get to grips with than the dark web. Despite several issues with my first order, I've learnt a lot through the experience.

I'm not going to say too much more publicly. LE and all that, you know.
 
Bleaney said:
It's been a very steep learning curve for me. But I'm brand new on there since the last couple of weeks.

There is a dark web level of products available, but it's been easier to get to grips with than the dark web. Despite several issues with my first order, I've learnt a lot through the experience.

I'm not going to say too much more publicly. LE and all that, you know.
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'LE' don't have the resources to investigate Gladys' stolen bicycle, let alone dedicate someone to trawl an ailing drug forum that peaked twenty years ago. But I understand your reservations, although I'm now more curious than ever.
 
JackARoe said:
When benzos became the standard prescription it seemed they really did find a way to take the kick out of methaqualone or barbiturates and created a pill that just hit even more specific (and boring) receptors.
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Would you say modest doses of benzos have more brain fog than modest doses of methaqualone and barbiturates?
 
red22 said:
Would you say modest doses of benzos have more brain fog than modest doses of methaqualone and barbiturates?
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My hazy memory of doing various barbiturates back in the day (secobarbital, nembutal phenobarbital) as well as placidyl ( which I liked the most) and quaaludes is that they were way the fuck more brain foggy than benzos. I would take them and be sleepy the whole next day. That was the feature that made me say "fuck that shit". I hated it. Maybe it's a peculiar metabolism thing with me. But benzos, no, though I've never taken huge doses.
Seconal I actually ODed on.Very foggy memories of that time 😉
 
chippermonk said:
My hazy memory of doing various barbiturates back in the day (secobarbital, nembutal phenobarbital) as well as placidyl ( which I liked the most) and quaaludes is that they were way the fuck more brain foggy than benzos. I would take them and be sleepy the whole next day. That was the feature that made me say "fuck that shit". I hated it. Maybe it's a peculiar metabolism thing with me. But benzos, no, though I've never taken huge doses.
Seconal I actually ODed on.Very foggy memories of that time 😉
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Lou Reed went into his appointment at the Vietnam recruiting office chewing on a Placidyl. Would love to have tried that!
 
red22 said:
Would you say modest doses of benzos have more brain fog than modest doses of methaqualone and barbiturates?
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Brain fog can be a term that can mean a few things. But benzos produce an effect that if you have anxiety it will take that away for a while. But a person might not feel much. The delusions of sobriety (which is fascinating as a drug effect) happen. Amnesia is big with benzos. Much more than say with alcohol or other downers in that aspect. Less effect on motor coordination.

Methaqualone is simply like drinking 5 beers in 20 minutes. Stumble around for a few hours like drunk. Not as much amnesia as a benzo. Or at least like alcohol. Most people can remember after a night of moderate drinking. Keep in mind I am going on memory from the 1970's-80's. I do remember it was game over (for me) when diazepam became the replacement to methaqualone and barbiturates for people looking to get "high". At least that is what we summed up. After that I don't think I touched a benzo for many years, a few decades. I have had one off scripts but only triazolam compared with methaqualone.

Barbiturates seem different than methaqualone. A true "downer". They were the downers we were warned about in school. Benzos were suppose to be a safer replacement and they are. One seconal capsule was much more sedating than a benzo and caused more stumbling around. Two or more can kill, especially with drinking. I remember when we tried to recreate with diazepam, had to take like 100 mgs and a few shots of alcohol and it was still not like a lude or a "red". :) But not as much brain fog with barbiturates on an average dose. But again, one average dose of a benzo causes me amnesia every time, or at least time gaps.

i don't really see a comparison with some of these downers. I mean maybe as much as we see a comparison from phenibut to benzos. They all seem a little different. But with benzos I do believe they did create a drug that took the kick out of what made other downers popular. More like anti seizure drugs instead of a "downer".
 
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So my three '2-Methoxyqualone' pills arrived as of 10 days or so, ago. And I've had two trials with them.

Unfortunately, either my 3 pills were massively underdosed, or I'm immune to the effects of the ingredients.

The best I could call the first experience was 'mildly pleasant'. With 2 pills, one swallowed, followed a few hours later by taking the 2nd one sublingually.

And it did feel quite pleasant to be drifting in and out of sleep on the sofa in front of the TV, just before going to bed. But until that point, I didn't really notice or feel anything different at all.

I've returned to the vendors group chat to check out what others are saying, and there is talk of underdosed pills.

It certainly looks like that's what I received.

And to add injury to insult, I also developed a small mouth ulcer for a couple of days afterwards. No biggie, it's cleared after a couple of applications of Bonjela. But it appears to have that in common with sublingual Etaqualone.

The only time I get mouth ulcers is after highly spiced kebabs or curries, and I haven't had either of those for some time. So it must have been the 2-Methoxyqualone.

People were talking about adding alcohol to the mix to activate the low dosed 2-Methoxyqualone pills in order to get something out of them.

Yesterday afternoon I swallowed my 3rd and last pill, with low doses of GBL. (I think it's very strong GBL.) Normally I'd never dream of combining GBL with additional downers, but these 2-Methoxyqualone even when they do work, aren't said to be highly sedating anyway, and I appear to have received some of the pills with barely any, if any at all, of the supposed ingredient.

I was also taking kratom and 2 or 3 teaspoonfulls of a weed enfusement.

Music sounded fucking amazing. But that was almost certainly at least 70% down to the GBL, maybe 25% down to the weed, and perhaps 5% down to the kratom and 2-Methoxyqualone "Quaalude."
 
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Perkins : Reborn said:
Ah, I was hoping this one worked out for you.

But no, shitty drug and ulcers.
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Obviously it would have helped if I'd received properly dosed pills. I can't really give the substance a fair review with what I ended up with.

But if this entire batch of pills is known for having unreliably dosed pills, then it's just a lottery, and I cannot recommend them.

Perhaps the other vendor that sells them will have better pills. But some people have apparently received good pills from the vendor I used.
 
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