• The Dark Side 💕 Welcome Guest 💕
    Posting Rules Bluelight Rules
    Notable Threads Urgent Hotlines
    Bereavement Mindfulness
    Suicide Support Anger Management
  • TDS Moderators: AlphaMethylPhenyl | paranoid android

Coming off Invega/Xeplion (paliperidone) injections v11

Status
Not open for further replies.
jrturp said:
Yes. Akathisia and some energy improvements were the only things I noticed until month 5. Month 5 is when the anhedonia started getting better for me. Cognition has improved too, mainly from being back on my ADHD medication. I’m now at month 6.
Click to expand...
if I remember correctly, you took 5 shots right? oh never mind
 
jrturp said:
Yes. Akathisia and some energy improvements were the only things I noticed until month 5. Month 5 is when the anhedonia started getting better for me. Cognition has improved too, mainly from being back on my ADHD medication. I’m now at month 6.
Click to expand...
What was it like when the anhedonia lifted? I’m about 7 months out right now and still feel like I’m at a constant 6 at all times. What about your adhd medication? Do you feel like it’s affecting you differently still? Mine makes my heart rate go up a little and I can focus with no stress but I don’t have a mood boost at all, but also no crashes anymore either.
 
Exactly 4 months now guys and how much of a challenge this has been. I want to firstly thank this community for their support, as people have been kind to me here although I complain all the time. It’s horrible I haven’t had hardly any improvements in four months, but I guess I’ll have to keep holding on. I do have a slight energy increase with akathisia easing and I suppose I’ll take that as a win. Anhedonia though has been hell and I have repetitive thoughts about suicide that keep coming into my head, particularly in the morning period. I hope that month 4 will be the month that I’ll experience more windows of improvement.
 
invegaloner said:
What was it like when the anhedonia lifted? I’m about 7 months out right now and still feel like I’m at a constant 6 at all times. What about your adhd medication? Do you feel like it’s affecting you differently still? Mine makes my heart rate go up a little and I can focus with no stress but I don’t have a mood boost at all, but also no crashes anymore either.
Click to expand...
is it fine to ask how many shots you took?
 
invegaloner said:
What was it like when the anhedonia lifted? I’m about 7 months out right now and still feel like I’m at a constant 6 at all times. What about your adhd medication? Do you feel like it’s affecting you differently still? Mine makes my heart rate go up a little and I can focus with no stress but I don’t have a mood boost at all, but also no crashes anymore either.
Click to expand...
I first felt it lifting when my baby smiling would make me smile and I could feel laughter again. A more subtle sign was finding it easier to get engrossed in a TV show. I feel similarly to you where I’m still flat-ish, just not as flat as I used to be.

Yes, I feel like Vyvanse and Adderall still aren’t working as well as they did pre-injections. Medication definitely helps with focus but isn’t as effective as it used to be. There’s no mood lift for me either. No heart rate changes though.

You’re about a month ahead of me. When did you resume ADHD medication and has there been any change in effectiveness since then?

I suspect sleeping 10 hours a night is a sign I’m not recovered, as I used to sleep 6-7 hours a night pre-injections. Have you experienced any sleep changes?
 
jrturp said:
I first felt it lifting when my baby smiling would make me smile and I could feel laughter again. A more subtle sign was finding it easier to get engrossed in a TV show. I feel similarly to you where I’m still flat-ish, just not as flat as I used to be.

Yes, I feel like Vyvanse and Adderall still aren’t working as well as they did pre-injections. Medication definitely helps with focus but isn’t as effective as it used to be. There’s no mood lift for me either. No heart rate changes though.

You’re about a month ahead of me. When did you resume ADHD medication and has there been any change in effectiveness since then?

I suspect sleeping 10 hours a night is a sign I’m not recovered, as I used to sleep 6-7 hours a night pre-injections. Have you experienced any sleep changes?
Click to expand...
I started taking my meds almost right out of the hospital when I was still on invega. I felt a difference immediately but not much. I don’t think I noticed the heart rate changes until a month or so ago? When I was in the hospital I was on risperidone and I had to sleep right after taking my meds and I slept for most of my time in the hospital. Now I sleep for 7-9 hours a night.
 
jrturp said:
I first felt it lifting when my baby smiling would make me smile and I could feel laughter again. A more subtle sign was finding it easier to get engrossed in a TV show. I feel similarly to you where I’m still flat-ish, just not as flat as I used to be.

Yes, I feel like Vyvanse and Adderall still aren’t working as well as they did pre-injections. Medication definitely helps with focus but isn’t as effective as it used to be. There’s no mood lift for me either. No heart rate changes though.

You’re about a month ahead of me. When did you resume ADHD medication and has there been any change in effectiveness since then?

I suspect sleeping 10 hours a night is a sign I’m not recovered, as I used to sleep 6-7 hours a night pre-injections. Have you experienced any sleep changes?
Click to expand...
I would suggest that the ADHD medication is not able to work as it normally would and while it is said the medications cancel each other out overall Invega is a much more powerful drug & works on far more parts of the brain than the stimulant.
Additionally antipsychotics also make ADHD symptoms worse.
I had sleep issues from Invega, It made me completely exhausted while also worsening preexisting insomnia, I spent months mainly in bed but unable to rest.

Source: The dopamine dilemma - https://pmc.ncbi.nlm.nih.gov/articles/PMC2898838/
"So where is the dilemma? According to mainstream psychiatry basic research and psychopharmacology, stimulant and antipsychotic medications have opposing mechanisms of action. Stimulants are thought to work by increasing dopamine (DA) levels between neurons, and antipsychotics work by blocking their effects at dopamine receptors. Concurrent stimulant-antipsychotic use has been rationalized by suggesting that they likely interact with different receptor subtypes and do so in different pathways of the brain. In reality, while the main therapeutic sites of stimulants and antipsychotics are different, they both interact at the same receptors sub-types and do so in the same parts of the brain. Examination of DA pathways has revealed that stimulants have significant activation at both the limbic system and the cortex. Antipsychotics have their strongest effects in the limbic system, but they have also have effects on the cortex.

Research on receptor subtypes has shown that the therapeutic effects of stimulants are strongest at D1 receptors, but they also have significant action at D2. The therapeutic effects of antipsychotics come from D2 antagonism, but these medications are actually unselective antagonists, being able to bind to all five receptor types. Going beyond theoretical implications, research has shown that stimulants and antipsychotics actually do block the effects of each other."
 
Last edited:
jrturp said:
Yes. Akathisia and some energy improvements were the only things I noticed until month 5. Month 5 is when the anhedonia started getting better for me. Cognition has improved too, mainly from being back on my ADHD medication. I’m now at month 6.
Click to expand...
Most people say it takes 6 Months for the anhedonia to lift. I hope mine will also be like that.
 
invegaloner said:
I started taking my meds almost right out of the hospital when I was still on invega. I felt a difference immediately but not much. I don’t think I noticed the heart rate changes until a month or so ago? When I was in the hospital I was on risperidone and I had to sleep right after taking my meds and I slept for most of my time in the hospital. Now I sleep for 7-9 hours a night.
Click to expand...
Is your sleep the same as before?
 
Trueart2 said:
Post more often @lostsoulowen
Click to expand...
Lol sure but there isn't much to talk about.
Personally i wake up, meet friends and smoke weed and vape.
I'm also researching solution for this horrible drug, i found the strongest way to get rid of this medicine.
I'm really good at using ai i used to program full stack with ai on serious coding projects.
He said Rifampin is even stronger then carbamazepine and could really reduce invega blood level.
I'm trying to get doctors here to prescribe me that but if i fail i might try in other countries.
 
RisperdalConsta50mg said:
Last week, when I was admitted to the hospital against my will, I appealed for compulsory hospitalization. Today was the hearing and I won the appeal. I can leave here whenever I want, even now.

That one doctor from psych ward stayed at my side and blamed the other psychiatrysts who did that forced stay against my will and she said he used nonsense and false things to justify the forced stay over me.

I will keep staying here in the psych ward because that doctor i meet here it’s on my side and he want to push for a PET and to find out what happened to my brain and what we can do to restore the damage.

Even the judge today was surprised about how “non-crazy” I’am and he cannot understeand why i was forced into a stay against my will..
Click to expand...
 
Status
Not open for further replies.
Top