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  • EADD Moderators: Pissed_and_messed | Shinji Ikari

Pregabalin / Lyrica

Inso said:
Did you guys know Oramorph (which I'm also on) is no longer a controlled drug but Pregabalin is? A doctor in a and e told me this. How the fuck does that work lol
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Because when it comes to the common opiates - codeine, DHC, and morphine - whether or not they are controlled drugs under the Medicines Act depends on how high the concentration is. This is possible because when medicines are designated controlled or uncontrolled, the form of the medicine as well as the ingredient is taken into account when the law is deciding if something is controlled. This is also why drugs prepared for injection are controlled more strictly than the same drug as a regular oral pill.

But as far as opiates magically becoming uncontrolled goes, that's why you can get co-codamol 8/500 OTC for example. Codeine is controlled under the Misuse of Drugs Act as a class B. But under the Medicines Act, as the concentration is low, it is uncontrolled enough to qualify as OTC.

You can even get OTC morphine in a 1mg/5ml solution called J Collis Browne's Mixture but it seems to be less available than it once was. I used to get it in bloody Boots! Not so anymore, none of them stock it now but as with codeine linctus you'll find it in the odd local independent pharmacy.

This is also why codeine linctus 15mg/5ml is OTC. Because that is the maximum concentration in which you can sell codeine as an uncontrolled medicine. Which ironically is higher than the US "lean" that is dosed at 10mg/5ml, controlled, and commonly sold on the black market for a grand a bottle ?

Going back to Oramorph, that 10mg/5ml concentration is juuuuust low enough to make it schedule 5 prescription only, but this is basically uncontrolled. However Oramorph Concentrated Oral Solution 20mg/1ml is controlled due to it being much stronger. Those morphine XR pills for example MST Continus are also CD's.

Other schedule 5's include those classic dihydrocodeine 30mg pills. But the DHC Continus are controlled since they're more highly dosed, even though one of the main reasons time release pills are used is to reduce abuse potential.

Yet another demonstration of how little sense drug laws make...
 
Combined 14 300mg Pregabalins with 6 Xanax's and it got me pretty wasted. I actually can't remember much of last night when I woke up this morning o_O
 
^ it was fun while it lasted:)

it seems that Preg and Benzos syngerise well together, for me at least, but obviously be careful and start off with small doses if you're going to try it
 
Forever Changes said:
Combined 14 300mg Pregabalins with 6 Xanax's and it got me pretty wasted. I actually can't remember much of last night when I woke up this morning o_O
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4200mg Pregabalin?! Most I've taken is 300. You must have been off your rocker. What was it like?
 
Inso said:
4200mg Pregabalin?! Most I've taken is 300. You must have been off your rocker. What was it like?
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I think the tolerance is so rapid that you don't really notice it. However if you're new to Preg I would definitely recommend starting low and working your way up.
 
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schizopath said:
Pregabalin makes people shadows of their old self, if used for long periods of time.
You will never fully come back from lyrica, so please keep that in mind when youre wanting to get on em.
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Is the same true for Phenibut? Are the two essentially interchangeable do you think?

But yeah I think I know what you mean, - I don't think tolerance ever resets back to zero no matter how long you abstain
 
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I dont think its the same for phenibut. Even benzos dont affect you as much in the long run.
I know many people irl who have become borderline schizos cause of lyricas. Like they are more scared and shit after using lyricas a long time.
Especially if you use lyricas with benzos/phenibut the effect seems to be even more rough.
 
Pregabalin is definitely a once in a while drug for sure. Daily use fucks your head up while at the same time tolerance builds to the fun parts. You end up with all the negatives and none of the positives.

Good one for the weekend though.
 
Lyrica makes your thinking cloudy as hell,seems to dumb you down by alot,which opioids not tend do in comparison.

Also the weird pharmacological mechanism makes it impossible to gauge the long term side effects you will get after many years of use.

It was introduced as non addictive,non tolerance forming drug,which is obviously total bullshit.

It has a horrible withdrawal which is like a combination of a opiate and benzo withdrawal along with crushing depression.My high dose lyrica withdrawal was almost up there with heavy heroin withdrawals.
 
Neithman said:
Lyrica makes your thinking cloudy as hell,seems to dumb you down by alot,which opioids not tend do in comparison.

Also the weird pharmacological mechanism makes it impossible to gauge the long term side effects you will get after many years of use.

It was introduced as non addictive,non tolerance forming drug,which is obviously total bullshit.

It has a horrible withdrawal which is like a combination of a opiate and benzo withdrawal along with crushing depression.My high dose lyrica withdrawal was almost up there with heavy heroin withdrawals.
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I'm on so many meds I'm surprised my organs still function. My mind is completely altered all the time. I've no idea who I really am anymore. I kind of like it.
 
Neithman said:
Lyrica makes your thinking cloudy as hell,seems to dumb you down by alot,which opioids not tend do in comparison.

Also the weird pharmacological mechanism makes it impossible to gauge the long term side effects you will get after many years of use.

It was introduced as non addictive,non tolerance forming drug,which is obviously total bullshit.

It has a horrible withdrawal which is like a combination of a opiate and benzo withdrawal along with crushing depression.My high dose lyrica withdrawal was almost up there with heavy heroin withdrawals.
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Absolutely. It used to surprise me how doctors bought into all this "oh don't worry, this new drug we invented won't be addictive this time like all these other drugs we've made in the past, we promise!" from Big Pharma but not any more. GP's in particular are just as clueless as any random bloke in the street when it comes to the drugs they prescribe. Most of them know absolutely fuck all. The higher up specialised doctors may know better but get paid off by Big Pharma to script the latest new thing anyway.

That's why you'll get psychiatrists telling you 5mg diazepam is "really addictive" but 300mg pregabalin is "absolutely harmless if you take it as prescribed... now let me up your dose again." Same cunt was also happy to put me on antipsychotics even though I've never in my life had psychosis.

Cunts the lot of them. Nowadays I'm tapering myself off these pills and smoking weed every day instead. Should have taken Snoop Dogg's advice long ago.

Still gonna keep benzos around for PRN use but that's it. No opiates unless I have surgery or something. No pregabalin prescriptions again for sure. No more fucking SSRIs or mirtazapine or quetiapine ever. Prescription drugs are some of the most dangerous of all, that's the biggest thing I've learned from my experience experimenting with them. Weed, acid, MDMA, all that shit didn't do me any harm. The crap being thrown at me by doctors did.

Oh and speaking of Snoop Dogg, reminds me, was having a chat with my mate about this just yesterday how music has started glorifying harder and harder drugs. It used to be rappers would talk about weed and maybe ecstasy. Now they're all on about Xanax and Percocet and OxyContin. It's creating a new generation of prescription drug addicts, or at least contributing to it, because you got young impressionable teens listening to that shit who are now getting benzo and opiate addictions to be cool instead of just smoking some weed like when I was that age. Happened really quickly as well.

At least there's still some acid rap...

 
As an opiod addict who has gone through heroin withdrawal and cold turkey methadone withdrawal at 40mg methadone a day before I just stopped. I ended up on lyrica (pregabalin) at roughly 300mg to 700mg a day for over 12 months. The withdrawal from this stuff was horrific. I have never felt worse in my entire life. The WD made methadone look tame in comparison. Twitches, vomiting, continiual nausea, diarrhea, stomach cramps and the feeling my CNS was plugged into an electrical outlet the entire time. I could not leave my bed except to go to the toilet. It also caused incontinence of tue bowel. I couldn't eat. I also had many feelings of doom that were unsettling, to say the least. I tried everything 8including methadone and clonidine to aide me. Even the methadone only put the symptoms at bay for 2 hours. The clonidine had a good effect but dis very little for the hastro intestinal effects which were the worst. The reason I wanted to stop the pregabalin were the effects (they were not side effects as they never went). Pressure buildup in my eyes and so blurry I couldnt read anymore. i put on 20kg (44.1 lb). I couldn't remember the simplest words and talking to me was like speaking to someone with a brain injurye. The drug WD is relentless and very discouraging. Statistically it helps few people and of those people it never helps 100% of their problems. Of the people it helps with pain only 3 out of ten will get a 50% reduction in pain, compared to 2 out of 10 and 50% reduction for placebo. Most people once placed on it will be stuck on it forever. Stopping cold turkey like I did can (like Alcohol) cause seizures. The OP is correct about Doctors and the Pharmaceutical industry both making and prescribing these new garbage drugs they make. In the medical literature they claim pregabalin WD syndrome is a cross between Benzodiazepine and Alcohol withdrawal: I can certainly vouch for this, if you can do it, and many cant because of how sick you become and how protracted it is. I also refuse to touch any of these drugs, they wreck your body, sometimes irreparably and the withdrawal is horrific.
 
There are new studys that show that gabapentin/lyrical halt the formation of new synapses. So basically when old synapses die in your brain,lyrical stops the formation of new ones,so on the long run you have less synapses in your brain. Also development of new synapses are stimulated by learning processes,those synapses have a configuration that help you understand things. On lyrica this development is stopped,so you could conclude that learning processes are not functioning properly when you take lyrica on a daily basis.
That also correlates with many reports of having cloudy thinking processes and worse learning ablilitys.
 
Wow sounds nasty, Cellsplode.

I'm only taking half of what I'm prescribed at the moment. Once a day 300mg. Hopefully that will help with addiction/withdrawals. If not the fact I'm saving 28 300mg capsules a month leaves me with enough to do a taper; if anything abrupt were to happen, that stopped my prescription cold.

Because that horror story sounds like hell :oops:
 
This is the honest truth and those on here who have known me for years like fubar will attest too it...

In 2015 i cold turkeyed from 180mg Physeptone pills (methadone), 5mg diazepam and 600mg Pregabalin per day (all prescribed by a pain clinic) ALL AT THE SAME TIME...

That the closest thing to hell in earth that exists (I'd been on all 3 for years to btw).

This isn't meant ad a dick sizing post but just to illustrate that drugs taken in good faith from a doctor can having devastating consequences if all stopped abruptly...
 
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