It's not necessarily a prodrug. If it is, then imagine it would have to go through 2 steps of metabolism, first a reduction to the alcohol (BOHB) and then methylation of the alcohol to give BOB. Some people may metabolise through methylation more effectively than others and this would explain why some people can't feel psychedelic effects of bk-2C-B at all. But then again you can't really rule out a possibility that people who can't feel it at all let it dimerise before ingestion.
It's possible that it's active on its own. If people who feel psychedelic effects of bk-2C-B didn't find BOHB as powerful, then the only explanation would be that bk-2C-B is active on its own. I've had this second possibility on my mind for quite some time now, however it's not a safe place to discuss such stuff. I'd rather have this lead to more knowledge about 5-HT2A receptors and their ligands than let the grey market make some money on it which would then be wasted anyway and which would inevitably lead to banning of some potentially beautiful compounds.
I've never tried either of those compounds. The qualitative comments for BOB in pihkal don't seem to be anything like my experience, except the duration, it doesn't seem like the comments on BOHD either, although BOD sounds similar to the end of the trip, possibly there's just a small amount of BOB or some similar compound & some other things going on too. The effects seem to change quite a lot at certain points in a BK-2C-B trip, after about 8 hours most of the visuals are gone for me & I'm just left with a lingering nice psychedelic feeling. I'm sure it's active on it's own as well, I got instant effects on exhaling when smoking it, it hit me just as quickly as nicotine & just before the cannabis, as far as I can tell, it's just not as strong as the effects that followed. Oral doses seem to be noticeable after around 15 or 20 minutes too, but only very subtly, unless I'm already on something, main effects don't really start for 2 hours. It's possible I wouldn't notice the immediate effects from smoking it if I wasn't already high on an oral dose, smoking ~20mg while sober seemed to do nothing.
I can't find any other reports on BOB or BOHD, pihkal makes BOHD sound a bit poor & nothing like I experienced on BK-2C-B, maybe it's just a scarcity of reports on those compounds.
Even if it dimerises, wont it turn back to bk-2c-b when it hits stomach acid? I'm not sure wrapping it up is necessary, but I have always wrapped it in cigarette paper & swallowed with some acidic soft drink. Should I drink some purple water for science? Water that has turned purple with bk-2c-b turns clear if I add a little vinegar.
It is quite possible to have a sober feeling trip on low doses, like some descriptions of 2C-B I've read, but milder & longer lasting. If somebody tries around 100mg & expects it to hit them like LSD, MDMA, speed or psylocin does, it just wont, it's a very slow & gentle come up, the effects can be quite subtle too, depending on set & setting. It can be quite mild & need a bit of a push with a little meditation or something, if it's not smoked or some huge dose I need to concentrate to get visuals, or it's just slight CEV, still feels very nice though. It's quite possible to sit & work, or sit at a computer and feel very little on it. I was getting great lap times on Gran Turismo, felt very focused, I wouldn't drive a real car in that state, but no problems with the game, I just felt focused. Maybe some people need a few separate doses to learn how to get what they want from it. I'm quite a light guy & sensitive to psychedelics, bigger people will need more, or maybe it's overpowered by some other drug they're on, or by drinking - it's potentiated by the weed I smoke. It's a much more clear headed and controllable trip than LSD, mushrooms or MDMA even, can go from feeling sober to tripping balls in a few seconds if I want to, or just stay sober if I want, on a sub 100mg dose at least. I can see how somebody could take it & feel very little, despite it being quite active if they were in a different setting.
I seem to have been getting better & stronger effects after using it regularly, no real significant tolerance except to the stomach effects, no comedowns or real cravings or anything either. Maybe it has just built up in my body, but it feels more like I learned how to use it. My back pain has almost totally disappeared too, I feel happier & healthier, I've got into the habit of doing a little exercise every day, stopped smoking cigarettes. I was improving anyway after going gluten free, but now parts of my back that I haven't been able to move for years & have kept me in pain are free & flexible. Possibly it could be a useful anti-inflammatory at sub-psychedelic doses. For me the first trip turned off my joint pain, depression, tiredness & 'brain-fog', still lingering due to my coeliac disease, I feel as good as when I was 20 again now, maybe better. I'm 33 now & I've been ill for the best part of 10 years, or maybe all my life, symptoms were really noticeable since 25, getting progressively worse until 5 months ago when I changed my diet. The joint/back pain came back a day or two after I came down, but it was much better than before, so I kept using it to stretch & exercise my back, now it's 90% cured even when I'm not tripping. It didn't cure my coeliac, not eating gluten does that, I still can't eat gluten, but it can take 18 months after going on a gluten free diet for some problems to heal. My father has much worse problems, he can't walk now, at least partly due to his coeliac & he has some kind of dementure, I'm his carer so I needed to sort my own problems out quickly to help him more. bk-2c-b was just going to be a warm up for a mushroom binge, I didn't expect it to fix my joint pain & get my mind in order straight away, but it's helped more than mushrooms ever could.
I'm even considering practising some yoga, no way I could've done that a few weeks ago.
Sadly I think the grey market is the only place where compounds like this can be investigated, I can't see many pharmaceutical companies rushing to research psychedelics. Hopefully nobody gets silly on it & tries taking full grams or more, vasoconstriction/circulatory problems & possible bad combinations with other drugs (esp stimulants) seem the main dangers so far, but unfortunately our government doesn't require any evidence of harm to ban a substance. They banned mushrooms despite nobody ever coming to any harm & them growing wild on nearly any open area of grass at this time of year, just that it might be a bit psychedelic seems enough to get it banned.