Gabapentin/pregabalin, cannabis (even most cannabinoids are great), phenibut.
I really wish tolerance to gabapentin and phenibut wasn't so insidious. I was prescribed gabapentin back when I was prescribed amphetamines for ADD, and it was wonderful at the beginning, and by the end I was taking about 2g and getting no effect except staving off withdrawals. It truly sucked ass, If i forgot to take it 3x a day I had an instant panic attack. I learned my lesson about gaba drugs though and never made that mistake with phenibut. Those two are only for occasional use, though they are great for an exceptionally stressful day.
Cannabis once a night has never lost effectiveness as an anxiety reducer.