I know everyone is going to flip out about me abusing this substance. Nonetheless, I should like to warn you of the potential effects of higher doses.
Thinking I had built up a tolerance (I had done ~10 mg insufflated three days prior), I ingested 22 mg orally and 22 nasally. I am not going to write a long trip report, but here are some details to consider: I've never tripped that hard in that visuals/synesthesia were constant and multi-layered; I abandoned my friend in Times Square in order to find my ex-girlfriend in Chelsea who I realized was "pure"; I walked up to a NYPD car and told them I was having a heart attack (my left arm was numb and my chest hurt, possibly psychosomatic, I suppose); in the ambulance I was convinced I was about to die and accepted death (a great feeling) but then was horrified to discover that I might never be allowed to die, instead being forced to ride around in an ambulance forever answering questions from retarded (I am serious) people who were unable to help me; in the ER I was convinced they were going to put me in a mental institution, even though the ambulance drivers told me they wouldn't do this to me; I could think quite well when I needed to answer questions, although I could not make sense of very many things which were said, in that everything was spoken in strange code (e.g. "gamma, beta, etc."); everyone looked either extremely comical or downright terrifying and a nurse who was highly caffeinated seemed to twitch and speak at 1000 mph.
Despite the terrifying experience of imminent death and/or eternal, torturous questioning and bureaucracy, I remained interested in my surroundings and accepting the entire time, despite moments of intense fear that I could not be understood. It seemed like a movie, or the "big joke" that is supposed to happen at the end of everyone's life. They gave me an IV and monitored my heart and took my blood pressure many times. I suppose I was all right though, because the head doctor did not mention my almost dying (I think I did almost die, however) and said that they don't worry about tryptamines really, unless there are impurities in the product.
I realized A LOT of things from this trip (e.g. INFANTILE HONESTY), as you may imagine, and I consider it the best thing to ever happen to me. I wouldn't take back my unscrupulous dosing decision even if I could. That said, it was physically and psychologically terrifying. Also, my right hand broke out into hives, which never happens to me, during the experience.
Be careful; contrary to what is said, you may not simply "pass out" at higher doses. I doubt whether I'll ever use a psychedelic again, as I learned enough.
8( 
