I don't rlly understand what you mean you gonna activate way more receptors with bupe ? How is that doing it since its only a partial agonist ?
I think I already tried to explain how... but I'll do it again.
It has to do with potency.
By the time you reach like 4-8mg of Suboxone, almost all of the opioid receptors in your body are completely covered. This is because bupe is roughly as potent as fentanyl. Yes it's a partial agonist, but that just means it doesn't have high intrinsic activity at the receptor.
Now if you took 4-8mg of any other opioid, it wouldn't cover all the opioid receptors in your body. Full agonists aren't meant to. If every opioid receptor in your body was completely covered in heroin, you'd die. Full agonists work better because they activate the receptor all the way, but when you use a full agonist, you don't need to take so much that it covers every receptor in your body, like bupe does, in order to get any effects or to stop cravings.
Plus every time you take bupe there's still left over bupe from the last time you dosed sitting on your receptors. So the fresh stuff is just gonna go attach to open & more available receptors. Bupe specifically, also starts to attach to different receptors once the dose is too high as well.
Bupe honestly should be in a category of it's own, cause it has it's own "high" and it's own sort of dependence, different from traditional opioids.
Some say this dependence/withdrawal is worse & others find it easier. I think it all really depends on personal chemistry.
And yes pregablin & gabapentin can help with the withdrawals slightly. I don't think they would for me, but I've been an opioid user for decades now.
I think you'll be okay depending on the length of time you used & how psychologically addicted to bupe/opioids you are.
Withdrawal will always be worse for me since I've been through it for so many years & no length of time away from opioids ever makes me feel better again.
So I'm stuck on them for life, which is fine with me because I like them, enjoy them & want to be able to use them.
But yeah, prepare for several weeks of anhedonia & depression once you stop.