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SSRIs are fucking crazy. I went through like 3 of them, then switched to SNRIs, then NDRIs... 2 hellish years of my life. Your depression is cured because you're so wrapped up in the side effects,
For real. Psychiatry is still in the dark ages right now, SSRIs are going to be looked at in the same way we view lobotomies 100 years from now.SSRIs are fucking crazy. I went through like 3 of them, then switched to SNRIs, then NDRIs... 2 hellish years of my life. Your depression is cured because you're so wrapped up in the side effects,
Kanna. It is a natural SSRI but surely has a different mechanism of action to the chemical SSRI's and likely does not interact in the same way with the same things certainly not in all cases I expect at least.
Kratom, I cannot tolerate it due to allergies and intolerances but I did take it for one month and I absolutely loved it or what you are seeking I found it to be amazing for my anxiety and I have a really extreme anxiety disorder about as extreme as can be much of the time.
Kratom was probably the best thing I have ever experienced for immediately taking away all of my mental agitation and anxiety and woes as soon as the effects kicked in in and instantly improving my mood and outlook.
You never mentioned Etizolam. I have found that to be very helpful with anxiety in certain situations and certain types of anxiety but probably not to the same degree as the kratom for example.
Also have you considered microdosing psychedelics like psilocybin mushrooms or LSD or the clearnet LSD homologues like 1p LSD, ald-52 and 1cp LSD?
SSRIs are fucking crazy. I went through like 3 of them, then switched to SNRIs, then NDRIs... 2 hellish years of my life. Your depression is cured because you're so wrapped up in the side effects,
For real. Psychiatry is still in the dark ages right now, SSRIs are going to be looked at in the same way we view lobotomies 100 years from now.
It looks like you've explored just about every anti-anxiety medication or supplement available... If you're not wanting to be on a bzd daily or an SSRI, I don't know what you're looking for at this point. It sounds like you need to turn inwards and look for the source of your anxiety and perhaps consider alternatives that aren't medications or supplements; what those are, I couldn't say. I just take bzds every day and my anxiety is managed well and I'm fine with that so I haven't spent much time exploring stuff like meditation, etc.
CBD is pretty much modern day snake oil IMO. I doubt it has much in terms of psychoactive properties whatsoever. I've given it a shot via different ROAs and none have produced anything noteworthy. I've found it virtually useless. It's abundantly clear to me that THC is the main psychoactive cannabinoid in cannabis, the others playing minor, or even non-existent roles.
valerian root is actually decent for anxiety. doesn’t hold a candle to benzos, but it’s way more than placebo.
tolerance builds quickly. and it makes you smell bad when you sweat. no biggie except during hot yoga.
YMMV, I find DPH to cause the most vivid and horrifying nightmares. Not great for relaxing.Another easily available, OTC thing that works prettty decently is diphenhydramine (benadryl). 25mg (1 pill) produces a calming and somewhat sedating effect. It really does help with anxiety.
For me, yes. I only use DPH in cases of allergies now, never for sleep because the nightmares are pretty consistent in occurrence.Even at 25mg?
Hallucinogens are a huge no-no. The first and last time I took acid was the worst nightmare I ever had that I couldn't wake up from. Whoever claims this helps their anxiety is confusing anxiety with something else.
Understand that I'm a very negative, cynical person who has learned to always watch his back and expect the worst. Thus, any hallucinogen or stimulant I take just greatly amplifies these feelings. If I start seeing shit, it's guaranteed to be negative and horrifying.
How can you be certain if you've only tried it once?
I suffer from bad anxiety and I've smoked dmt about 10-15 times. 99% of those experiences have been good. 1 negative/challenging experience which could have been avoided.
What's causing your anxiety. Is it drug induced or something else?
I know you wrote off beta-blockers and such in the beginning post, but if you are focusing on adrenergic effects and don't fare well with some serotonergics and have tried a bunch of gabaergics, it may be worth trying one as a PRN. They are WADA banned from shooting sports and such for a reason. Propranolol can also be used to modify fear evaluation and thoughts.
Buspirone has a metabolite that can be an a2 antagonist which doesn't mesh well with some people. I believe a2 is essentially an autoreceptor, wherein normal DA/NE leads to negative feedback damping the signal. As such antagonists can be stimulatory, though reality and interactions are more complex. A comparison would be yohimbine. Would likely be fairly anxiogenic for you, haha. A agonists like guanfacine and clonidine are used second-third line for ADHD and help some people who have trouble with stimulants. Usually more of a daily thing though, and they have rebound. Of course everyone is unique, and some get bothered as well.
I mean, if your established thoughts from the environment you grew up in are behind your distress, it seems logical to go after them with therapy. We can build defense mechanisms that may have fit the situation in the past but are destructive now. I was in a DBT group with a lot of people who had histories of abuse and didn't want to give up the safety of previous defense mechanisms because of fear of being taken advantage of again. Not everything has to be CBT or something like that. Recognizing the situation and the motivations / drivers can be beneficial. On more than a cerebral or disconnected level, I mean.
Reviewing what led the practice of being defensive to being the default mode, trying to balance protecting yourself and engaging in life, both are some ideas to explore. I've found the protection of cynicism and forced stability overrated outside of manipulative environments. Excessive negativity. I realize that is a difficult spot when you had someone who told you you were a certain way in the past, and the whole idea brings baggage/trauma. Shutting down from reacting can prevent connecting to good things and make an outward appearance of depression, even if it stemmed from a self-protective area.
I mean there is a difference from pursuing mood stability in bipolar disorder vs. mood stability in OCPD or excessive anxiety, of course.
but I say dependency is better than agoraphobia.
I've seen Nelly from Drugslab freak out on that stuff
What does etizolam feel like?
Are you talking about this video?
They're definitely not suitable for everyone but I think you're looking at psychedelics with the wrong mindset. I can understand if they aren't for you but they're a long term fix for anxiety rather than a short term like benzodiazepines and other related drugs. You often hear about sufferers of anxiety who have managed to overcome it successfully explain that you need to understand how to deal with it differently before you can beat it. Psychedelics are the key to doing this for a lot of people. It's a long road to recovery believe me but I've finally found a few things that are actually working and giving me a lot of relief.
Instead of saying what drug can I use/take to deal with the anxiety I'm now looking at it like, How can I look at/deal with the anxiety differently to make it more manageable.
One of my first few questions should have been, Have you considered getting a blood test for hormone levels?
Low testosterone can cause many of the symptoms you've described. After a cycle of testosterone recently I definitely noticed increased confidence and mood stabilization whilst on the testosterone.