Guess what... I just did a trial of 5mg of (supposedly) 2C-I from (edit), taking it at 2:30pmg orally in juice, and was going really great - I had fasted all day and it hit me within 20 minutes, and was quite enjoyably 2Ced, in a much more stimulatory manner than I am used to from 2C-T-2... I kept saying it was similar to rolling or to having taken "5mg of T2 and a 5mg Dexie/25mg MDMA". t+2h and it's more like "5mg T2 + 15-20mg badly cooked meth/50mg Ritalin"... and after that it turned into The Ultimate Dopaminergic Nightmare (C).
It's safe to assume this doesn't usually fucking happen, eh? I felt like I was on incredibly, incredibly dirty speed this time, and the terms "idiosynchratic reaction," "Beth state," "Set and Setting (or why not to listen to AC/DC and smoke over 1.5 grams of two powerful strains of weed while not paying attention to where one's mind is actually going coming up on experimental psychedelics," and "breaking a 24 hour fast with Cadbury's cream eggs" ran through my mind. I was able to hold on because I have (relatively) extensive experience with amphetamine overdose, and ayahuasca has trained and taught me to deal with Weird And Unexpected Shit (TM). I appeared to have some fucked up Blood Pressure Issues (R)...
I got to sleep at 1am this morning... I had taken 1.5mg sublingual melatonin at 8:45pm, again the same at 9:45pm, and then snorted (heh.. it works WELL, btw) 1mg extra melatonin as a rescue agent at 12:45am.
I was the whole time, and am, acutely aware of the presence of 50mg of l-tyrosine (THE amino acid dopamine/(nor)epinephrine precursor (!!)) and 50mg l-glutamine in a powerful "peak performance" multivitamin I've been taking... I took two during the day I dropped - one when I woke up, one roughly one hour after I had taken the 2C-I. I had read many reports wherein 2C-I is described as one of the more intensely 'speedy' 2Cs, and have had much interesting thought in regards to the large, heavy, symmetrical "quantum field thingy" (so stoned!) of the iodine atom having potential similarities to the same for the methylenedioxy ring on MDMA, so I was not surprised that it was initially much speedier than 2C-T-2... two hours later it was apparent that it was waaaaaaaaayyyy too fucking speedy. I've smoked gentler half grams of street meth, for the love of the god of fuck. I guess that's 'body load,' huh? Perhaps it's a bad idea to do the whole dopamine preload thing... even if you don't know you're really doing it. Thankfully it was in a multivitamin - standard l-tyrosine supplements are of 500mg size - Ouchhhh (!!).
It's disconcerting to think that taking as little as 100mg of free amino acid l-tyrosine while one is fasting, and only 50mg while one has a dopamine-lookin' compound in one's brain, could potentially shift the equilibrium at dopamine production sites enough to cause a potentially dangerous catecholamine cascade!
Or did they send me 2 or 2.5 or 3g of the stuff instead of 1g, assuming I'd weigh it on an analytical balance rather than make a standardised solution? Or did they send me 2C-T-21, which might indeed kick my fucking ass at the originally planned 10mg?! What damnit?!
I _SWEAR_ I shouldn't have broken my fast with Cadbury's cream eggs... that's where it started to go downhill. Which is Unfortunate (TM), because I thought it was THE ABSOLUTELY BEST SHIT EVER until then... I mean, wow... I couldn't picture 2C-T-2 with more colourful visuals, more euphoria, and non-existent body load until now. Wow... I thought MDMA had NOTHIN' on this shit.
So I'll be trying a re-challenge a bit later on, without the fucking tyrosine, or the fasting for that matter - I might wanna have calories floating around in my system in case I decide to move around occasionally.
It appears the egg-laying miracle Jesus chicken came back to life this weekend. The fucker's going around malevolently tweaking trippers' excitatory neurons and HE MUST BE STOPPED...
and:
Further Thought, or My Current Working Model of the Activity of The 2Cs Which Is Hopefully Not Skewed To Death By Personal Idiosyncrasy
The 2C-series compounds appear to exhibit the sweet-spot dosage phenomenon, wherein the optimal dosage lies within a certain range, depending on the individual user’s tolerances and metabolism, with both lower and higher doses being undesirable in comparison to doses from this range.
I personally have much more experience at the moment with 2C-T-2, which I have taken perhaps 12 times in doses ranging from 8mg to 20mg. At the range of 8-14/15/16(?)mg there are only very minor threshold effects, similar though different to threshold doses of dextroamphetamine or MDMA, and the presence of the classic 2C-‘clench’ which can be distracting and/or irritating. However, a remarkable change occurs at the 14/15/16mg level, where the unique psychedelic effects suddenly manifest themselves in full force with either no change or an apparent decrease in the 2C-clench. In any case the clench becomes FAR less noticeable, one is too busy tripping one’s balls off and having a great time. It may even mutate into a body buzz if your particular bodily rhythms facilitate.
(This is an attempt to ‘filter’ any tyrosine effect from my trip and may be totally erroneous) My experience with 5mg of 2C-I was very similar to my 8-10mg (in retrospect) 2C-T-2 experiences, being much speedier and much more enjoyably visual (it’s equally visual but just has better visuals, if you know what I mean), and much more ‘serotonin-y’ (see above iodine/MDx comparison) and thus more purely enjoyable, except with a shift in the way the drug affected my circulatory system – 2C-T-2 tends to present me with the issue of higher-blood pressure and thus a tendency towards headaches, so I tend to take 500mg-100mg paracetamol with it at the time of dosing to minimise this.
Perhaps this was another mistake I made with the 2C-I – I took 2 paracetamol tablets in advance, expecting that the reported headache was one induced by HIGH blood pressure.. it appears it might be instead a LOW blood pressure thing, which I would have been made much more susceptible to by taking the blood thinning paracetamol. Perhaps this is to be avoided. (Perhaps I’m trying to convince myself I didn’t just spend a shitload of money on a really crap drug).
Anyways, it seems that two (somewhat daunting!) more trials are to be made with the 2C-I in order to clear this ishyou up – one clean, tyrosine, paracetamol, pot-free 5mg trial, and then a higher (argh!) dosage level trial. Perhaps I’ll goddamn the torpedoes, it’s for science. Except, you know, it’s also, like, my brain, and I wasn’t, like, totally impressed the whole time last time, dude.
In any case... it seems the 2Cs need to hit a specific serotonin receptor subtype to have their goodness manifest properly, unlike what I’ve found with the tryptamines, which seem to manifest much more interesting and diverse effects over their dosage ranges (because they hit so many more receptor (sub)types in so many more places!), and that this specific serotonin receptor subtype may not be the receptor subtype that the particular 2C compound in question has the greatest affinity for! This could account for a LOT of the variance in experience with the 2Cs and why different people may have such a wide range in their own particular sweetspots… or perhaps I’m just way too stoned and I’m rambling and I think it’s all profound and shit. Whaddayathingk?