2C-B, along with 2C-C and 2C-D, are the only phenethylamines I'd feel comfortable taking to the 100+mg level. All three are very easy on the body, and do not feel in any way 'toxic.' I've had 2C-T-7 all the way up to 70mg, and it was WAY too much and felt very dangerous. Amazing experience, but I am very happy with the 30mg-60mg range.
I can definitely see me trying 2C-D at the 100mg level one day....short, easy on the body, and very introspective at the 20-40mg level. I bet it will be mind-blowing at higher levels.