Recently was prescribed Zoloft daily for depression and anxiety, i took my last dose about 14 hours ago and I'm skipping today's dose. I plan on taking 250mg tramadol and 25 mg of Vicodin in probably 3-4 hours. Would this be fine? I've taken doses of 750mg of tramadol with a regular dose for about 4 months of 500mg also I've taken about 60mg oxycodone daily before tramadol. I stopped for about two months now and just wondering if my dose would be fine with Zoloft dosed 18 hours before. Also plan on drinking tonight as well, any input?
