Tough, i got mad love for both, but i have to go ith 2C-E, done it waaaay more, and allways loved it 4-HO-DET i only did once, and it as great, but still i'll stick with 2C-E!
Driving a speedboat on 100mg MXE sublingualed
or
Driving a car for the first time (automatic gears) with no training on 500mics of LSD?