Comparing drinking twice every weekend to once a week mdma use is a joke. To severely etarded I also don't have any meth in my pills, I have them tested and have got from the same guy for 2 years. I don't fiend I just wasn't into drinking at the time and thought it was alot funner doing mdma at the club. Didn't go for that long because obviously the good effects diminish and the bad side effects get greater. People can get addicted to literally anything, but the state a drug puts you in is much more desirable than most things. All of your serotonin was never meant to be released but damn what an experience it is.
Again the point is when most people start they have no clue about harm reduction or anything. I remember I was peaking my first time and we all went out for a smoke. It was a bunch of our first times and we were just having one of those talks. I have an addictive personality, I was going off about how much I loved this shit. I said not gunna lie guys I'm probably gunna do this every weekend, little did I know... I agree with Folley though I think it can be used responsibly if you wait a good 3 months, I say 6 months would be perfect or even yearly, no redosing, a nice starting dose around 100-120. This will never happen though because some people aren't educated and won't research the stuff, as well dealers will always put shit in pills and not everyone is going to do the acetone wash.
I just started using responcibly the last 9 months and I've lost any problems I had. The thing I regret more is I might not regain the magic but maybe with a nice eight month break I've started I can get it back. My last roll for example was on new years, and the only problem I've had since the roll was memory was off. I don't know when most serotonin regenerates but I just had a test yesterday and I aced it. Got 95% on it and remembered everything I studied clear as day. I don't know if 5htp works for this but I just go insane on bananas and oranges, I've easily had over 100 bananas the last month.
Point being last time I didn't follow harm reduction I popped at about ten oclock and then popped another at 3 in the morning and then two weeks later redosed three times in a night, smh. For up to a month later I would feel depressed throughout the day for no reason at all, maybe a month and a half. Simple though you abuse the drug your gunna have major major problems, and if you use it safely or as safe as you can then you probably won't see any problems. But don't say weekly use is comparable to weekly drinking, just makes you look like an idiot and one of the reasons I started this post.
I consider myself the luckiest person alive because I have been blessed with the opportunity to study Neurology at the University of Colorado. Not the best school in the world for the subject, but a very, very liberal university thus allowing for some extensive "under-the-table" studies in the lab. My professor, who will remain nameless, has allowed myself and others to do some in depth studies with MDMA, mostly using ourselves as test-subjects, and here's some interesting information for those of us who advocate the drug, as well as everyone else who stumbles across this thread.
First of all: harm reduction is NOT bullshit. It is not only legitimate, it is absolutely essential. MDMA can have some staggering negative side-effects especially in the short-term, and simply put - the better you take care of yourself the less damaging MDMA is. Everything from diet, exercise, sleep patterns, hydration etc... All of the stereotypical good health habits. As well as - and this doesn't get mentioned much - but healthy relationships. People who have healthy interpersonal relationships tend to have better monoamine balance in general, including of course our friend 5HT, "Auntie Sara" "The tonin' of the Sara"... lol.
I have found for me personally, with the proper amount of time between doses, it seems as though my neurotransmitters have infact sensitized to the effects of MDMA in the therapeutic range. For me the TR starts at 130 mg and discomfort begins around the 200 mg single dose; eyes wiggle too much, vision is blurred, lock jaw is extreme. Still a good feeling but not the introspective happiness/feeling of self-worth and empathy that I am looking for when dosing Molly.
Obviously our test segment is small. To be exact there are 7 of us who use the drug and document our experience and the effects, both negative and positive.
In short, it appears that our brains are capable of producing much, much more serotonin then they currently do based on the law of averages. The theory I and my colleagues have developed is that, in the past, the lifestyle of the human being was much different. Think about living in a tribe of 100 people, all of whom you love dearly and would do anything to protect. The presence of chemicaly like serotonin, **oxytocin**, dopamine, epinepherine/norepinepherine, adrenaline etc. would all be present in a much gerater quantities. Just imagine the feeling you get when you meet with 20 family members on Thanksgiving. You walk in the room and immediately feel warm, cozy, comfortable, and full of joy. These feelings are natural, but they are still controlled by neurotransmission. if your brain gets used to producing these chemicals in higher quantities, it will continue to do so on a consistent basis. In the past, togetherness and community had much more emphasis placed on them and were much more common. Thus increasing the presence of the chemicals we are talking about when we discuss MDMA.
In the same sense, as you introduce MDMA in to your brain periodically in appropriate doses/timeframes, your brain will begin to "figure out" what to do with it and therefore use it more efficiently and effectively. Clearly the opposite applies if you overuse the substance. Yes, our brains may be able to produce more monoamines than they currently do, but as someone stated earlier in this thread - messing with brain chemisty is an art, and a very fragile one at that.
I could go on for hours about all of the amazing stuff I have learned about the drug MDMA specifically, but I realize I am running in to the crucial point where "No one gives a shit anymore" haha, so I will leave you all with this. If anyone is interested in hearing more or has any specific questions that I may be able to shed some light on, please let me know and we could start another thread entirely and possibly attract more knowledgeable folks who could bring to light even more "cool shit"!
Love all of the insight I have gained from this thread alone. I study this stuff all the time and I have still been presented with ideas and theories that I would never have thought of. Pretty amazing stuff!!