DJ 303
Bluelighter
I've heard if you mix poppers and meth then do squats you will be build like a shithouse in no time
ive heard that 91% of all statistics are made up on the spot, and thus entirely useless as evidential proof of any worth.
I've heard if you mix poppers and meth then do squats you will be build like a shithouse in no time

If aspirin was reducing the viscosity of the blood then it could possibly reduce the blood pressure, however the term 'blood thinner' when used for aspirin (and most anti-coagulants) is a misnomer. Among other things, the drug inhibits the formation of thromboxane A2, a lipid that increases the ability of platelets to aggregate. Therefore, aspirin is just reducing the ability of platelets to clot, not reducing blood viscosity.
The thromboxanes are also involved in vasoconstriction however, and vasoconstriction can definitely lead to increased blood pressure. However my understanding of it is that this vasoconstriction mainly affects coronary arteries and when it is not functioning properly leads to a certain type of angina. I don't think that aspirin will have much effect on the catecholamine induced vasoconstriction of methamphetamine.
You are right that the dose of aspirin required for this is low; 80-100mg will suffice, and at that dose there should not be adverse renal effects unless the person is quite dehydrated or already has renal problems.
(and to get to that age as a tweaker they must have been taking it)Now i am thinking about alpha or beta blockers for adrenergic vasoconstiction. Whatya reckon Mr Blondey??
Yeah, apologies. I'm probably not in the BEST state atm to be reading/replying to posts with exact precision, but doing the best I can lol!
The reason I signed up to this forum was for Education/Harm Reduction and having already learnt so much in the short time I've been here. Will always welcome criticism and advice with open arms! No offense taken and hoping I myself haven't come off as being a dick reading through my previous posts![]()
Now i am thinking about alpha or beta blockers for adrenergic vasoconstiction. Whatya reckon Mr Blondey??
i think youre entirely failing to see my point here!!
Have you actually read the sentences in this thread?
did you understand them?
Cause thats my point mate - you go hard! well done man - do you want a medal?
Do you think that by "cramping up due to substantial sweat loss"
and "pushing through to recovery clubs"
or "taking several substances along the way"
You aren't doing any damage????
This evidence of your apparent "hardcore" group of mates, makes you immune to future issues?
My point is, it's in the mail, coming to a party near you soon!
I've cained it too mate - you aint the first.
i aint hear to start cocksizing, but, don't even get into a conversation about how harcore you and your mates are.
You will lose.
My whole point is that you cain it, you get away with it, but nobody gets away with it forever!!!!
especially if you can't even manage the simple task of staying rehydrated!!
take it easy man!
this is harm reduction!
^Yeah I posted earlier on that there will be unopposed alpha adrenergic problems with this combination. The problem seems to be worse when beta blockers are used with cocaine though.