Best for what purpose? IMO the best PED will be the one you can run for enough time to produce significant results without experiencing serious side effects.
It all varies, wanna lose fat? Retatrutide is likely your best bet. bodybuilder peaking for a show? Yeah youre gonna have to throw the whole kitchen sink at it, but the average guy doesnt need trenbolone as it will just cause issues.
Speaking strictly regarding AAS id say testosterone + a secondary compound you tolerate. A lot of guys will experience hairloss from DHT derivatives and get significant mental sides from 19-nor derivatives. This unfortunately narrows down compound selection a bit, but if you tolerate DHTs well then a decent dose of testosterone + primobolan and then GH and insulin will have a great synergistic effect and be tolerable mentally while not skewing bloodwork much, could also use boldenone instead of a DHT.
You could even do some unorthodox cycles like just using boldenone + injectable estradiol or either high nandrolone or boldenone + a really low dose of test say 50 - 70mg. This would ensure minimal hairloss and effect on prostate, just be aware that nandrolone is both neurotoxic and cardiotoxic.