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  • BDD Moderators: Keif’ Richards

What SSRI/SNRI has worked best for you?

My question is...
Why have the American pharm companies not come up with novel antidepressants like other European/Asian/Russian ones?


^^A slow creep back into old ways.^^
 
noticed today (day 3 on lexapro) that I was experiencing strange visual distortions in the dark. Things would get very dark then look like they were morphing and when I moved my head stuff got bigger and smaller.....this also happened to me on day 3 of taking celexa.....I know this is a rare side effect, but to be honest it does not really bother me, it is actually kinda cool......anyways just wondering if this is anything I should be worried about? And did anyone else taking celexa or lexapro notice strange visual distortions in the dark? My eyes are pretty dilated (common side effect), but when I look at my pupils in a mirror in a well-lit room, I notice they are constantly constricting and dilating......any input?
 
I am one of those people who had to try literally all of the available SSRIs until I found one that worked. The one that worked for me (I'm diagnosed major depression, anxiety, ocd, ptsd), and continues to work for me to this day is: Luvox (Fluvoxamine). I take 100mg in the morning and 100mg QHS (at bedtime).

Other SSRI's that worked for me, though not as well as Luvox were Lexapro and Celexa. Lexapro and Celexa are very closely related; something like one molecule away from being the same chemical.

There you have it; my $.02 - hope this helps somebody out there ;P
 
Prozac-I took this in 5-10mg and it worked but I did not enjoy the sexual side effects which I eventually got over.

Zoloft-I took this in 25mg and it worked very well and it was like Prozac lite but towards the end of taking it I was very stupid and I started binge drinking lots of booze daily and this made it stop working and I did worry about frying my liver but I did not and I also smoked a fair amount of herb on it. Zoloft did work wonders for horrible debilitating anxiety/panic attacks I was having and depression as well.

I had tried things like eating better food-fresh fruit/vegetables, taking vitamins, getting bloodwork done, exercising pretty much daily, meditation, and all of this did not really help the depression/anxiety/OCD at all and I was in therapy too and that did help a bit but not as much as the medication with the cognitive behavioural therapy did. Also at the time I was horribly depressed and very anxious having almost daily panic attacks and not sleeping for days-no I'm not bipolar or manic I was just getting tons of anxiety then-I did not use any drugs at all even booze and I did not even drink that much caffeine.

Multiple doctors refused to give me any benzos for the panic attacks/anxiety I was having and that's a very good thing since I probably would have abused them and gotten addicted to them or when I was binge drinking daily in my early 20s done something very stupid while blacked out from the benzos and booze. Also I had friends who have taken or take Paxil and they told me horror stories about it and I did not want to take Paxil so I took Zoloft instead.

Wellbutrin-I took Wellbutrin XR 150mg for about 2-3 days and I did not like how it made me feel more anxious and like I had drank a lot of caffeine and stayed up for a few days without sleep even if I had gotten sleep that night.

Lexapro-I've taken this in 5-10mg and I'm still on it and it's by far the best SSRI I've taken as it does not have horrible side effects. I have OCD, anxiety, and depression and it works for all three of them.

St. John's Wort-I know it's not an SSRI or an SSNRI but people seem to claim how it works for them and how since it's a natural herb that it's somehow good and better than a man made drug. I did try taking SJW and all it did was make me very bitchy, angry, and I wanted to and did physically fight people as odd as it sounds.

I've never taken a TCA/Tricyclic and those are not really prescribed anymore and I've heard they can be hard on your body.
 
pbear14 said:
Are you seeing a psycologist(sp?)? I am almost positive that you have Clinical Depression. You really need help! I once had all the same thoughts as you. My mind was insane. I went and saw a psycho therapist and he really helped me. Do you have any insurance? If not, would you be willing to go get county medical help. IDK where you are from but everywhere offers some sort of medical insurance for at least temporary times. I think you should specifically ask for Paxil, because it covers so many of the "different kinds of anxietys" Also talk to them about a Benzo. One such as Xanax. even if they give you a low dose, I think it will give you extreme relief at the times when you feel like exploding! Benzo's can be VERY addicting, as I"m sure you have heard before, but I do believe that you need something that you can take to help calm you in intense situations......or at least until the Paxil kicks in. And remember....all anti depressants take more than just a few days to start working. Also, I have been on Paxil for so long, IDK what other ones have came out to treat people like us. There might be better ones now days.....IDK? Just talk to your Dr about the best for you.....and if he doesn't prescribe Paxil and the one he does prescribe to you ends up not ever really helping, then thats when you should specifically ask for Paxil! I swear it changed my life! But I had to go through quite a few other kinds before I told my Dr that I absolutely wanted Paxil
Good Luck! I hope I did more help just now than I did rambling. lol;)
Click to expand...

I gracefully thank yu for you attention and the time you took for answering my 'question'.

BTW i'm from Italy and post in ADD so i guess i know a few things.

If i have to be honest i've been a meth addict years ago, but then meth wouldnt do aything to me apart from making me stare at the wall endlessly or getting hypersexual (on the net, you know what i mean )to the point where i you kist pass out from sexual exhaustiaon.

Benzos, HAHA, ive been a benzo addict for almost a year i startet to take liquid rivotril (clonazepam) not as a theraphy but as a 'escape route, the tollerance went up fucking fast and from 4 mg a daysi went up to 30-40mg a day intravenously, yes you heard right, i was injecting oral drops. until one day i suddenly decided to stop and after 5-6 days i has my first seizure due to the fact thati was supposed to taper down instead of just cutting off right away, clonazepam is also used as an antiepileptic, so as u can imagine, from having my GABAa heavily stimulated and desensitized i went to a state of abstinece which cause glutamate aboundance and seizurres, 4 so far. to be honest i found a way to fake prescriptions so i could have all the conazepam i wanned and lets not talk about all the otherdrugs i took during that period, in sort words whatever got me high i would take it, apart from amphetamines, meth and MDMA which made me psychotic.

This benzo discontinuation didn't really affect e psychologically as long as i was being entertained by some friends (but life, universe and what not seemed so hopeless) but then seizurers came along and i was hospitalized for more than a week, they firgureout that i want epileptic but then i told them how much clonaepam i was taking IV they hardly believed me.

My GABA tolerance hasen't changed much since, i remember taking 200 mg (20 pills of zolidem and felt almost nothing, still i ave to admit that i drin frequenlty cause thats what makes somhow euphoric and non caring, so in some way that aso accounts to my GABA tollerance.

MY idea was to get prescribed to paxil and small ammounts of wellburtin + plus obviously having a radical change in life style cuz there is nothing like a happiness pill if you sit all dy in fron of your PC feeling anhedonic (unability to feel emotions).

MY ambitions are close to zero for now and my creativity seems to have taken a loong vacation, i'm having great probles with my attention and with my ability in feeling interestin me or others. Also my confusional state keep getting worse even if im abstinent, apart from cgis and occasionally alcohol.

I'm currently taking Valproic acid (a GABA transaminase inhibitor0 which is supposed to prevent any further seizure and stabilize my mood, but i desperately want to get hold of my memory and my emotions so bad. I'm sick of not remembering people i have met or forgetting things i have read. it becomes embarassing to hang out with people when you know you know that you are simly 'weird' and can't interct with them the way I sed to.

For now im hoping on paxxil and some wellburtin, but i also ned something to gain back my memory, im just 21 and i've been close to suicidal many times. It's not worth it in my opinion because im a intelligent person and, not to be cockyl, a good looking guy, but unfortunately this 'disease' has been following and worsening with time making me loose friends, girlfriends, jobs, stucy and what not.

Thanks for you attention, i wish the best for all fo you.

CIAO
 
ZOLOFT works great for me, but perhaps it just augments benzodiazepines and amphetamine well for me (all rx'ed), it helps major with depression, but oddly enough, not for anxiety.
thumbs up.
 
I wanted to see my plych to ask for paxil but for now I just started taking effexor 75 daily since 4 days, i nkow that means nothing i i beliebe thatsomehow it has changed myenergy somehow and im a bit moe wiling into geting involvdin conversation rather than avoiding people. if this doesn't turn out goofin a week or two then im shifting to paxil.

Anyone else had exoerience on effexor, got something to share?
positive negative long term side effects?
 
After quitting Paxil, the detox wound me up in jail/ mental hospital. That was the worst experience of my life.
then comes lexapro, and I couldn't get happy at all...ever.
Now Prestiq, It's OK for now, a little more energy, still no real joy.
The SSRI train is a looong bad ride for some, especially for me.
What I think I want is ADD meds, coupled with low dose Klonopin used PRN, as I can't stay on track on anything in my life. I've never read an entire book, watched a whole movie, really listen to a friend's conversation. I always have songs playing in my head 24/7. Great songs mind you, but makes it hard to concentrate on anything.
I'm what people call superficially bright. I seem cheery and attentive to all. Each morning though, I'm very sad that I actually woke up again. I would never kill myself, but every night I pray for god to bring me home with him. I'm afraid of nothing. The worst neighborhood, the meanest person, I'll get your purse back from a mugger, I'll break up a fight, I'll jump from a plane, You get the point.
Such is life
 
When I quit paxil, I ended up an absolute fucking mess, I could not move without vomiting, I had auditory hallucinations, I was sweating probably almost literally buckets of sweat, it's ghastly.
 
I've heard they're coming up with 'serotonin reuptake enhancers now'.

Kind of ironic isn't it.

Anyway how efective is paxil as an antidepresant compared to others, ive been on effexor 75x2 daily for about a week...but im really intriegue in paroxetine.
 
BTW has anyoneelse experienced reduced sexual drive on effexor?

I do masturbate sometimes, but not for the urge, just because....'i'm supposed to'.
Ejaculation is also very weak compared to when I wasnt taking it.

And that 'spark' that normally gets me in the mood of seducing a girl is really low.
 
Only tried paroxetine and citalopram. I was on citalopram and xanax for 7 months, they took away depression and anxiety, but I'm not sure which was effecting it, I think both. After that haven't experienced any depression but I think my journey to psychedelics fixed it. Paroxetine made me yawn all the time, pretty strange side-effect, tho' ate them only for two weeks, also killed my libido completely.
 
Today is day 12 (I think) of Lexapro. I've had some side effects: Slight nausea, shitting like a race horse, minor headaches and a little anxiety. Yesterday was the first day I actually could say that I felt it start to work. I hear from many people to give Lexapro 3 weeks to even feel it's effects. Anyone have any input? Did anyone have some anxiety when starting Lexapro? Maybe it could also be that I'm down to 20mg of paxil (from 60mg) and the coming off the old med and waiting for the new med to start working is causing it. Make any sense?

Btw, thanks for all who have contributed to this thread so far. I also believe some people are born with a chemical imbalance. I hear a lot of "f--k SSRI's" on bluelight; however, unless you've have been clinically depressed or have an anxiety disorder, you'll never know how much they help improve lives.
 
I have tried almost every antidepressant out there with the exception of MAOIs none have done a noticeable thing to me. With the exception with caused insomnia which led to a manic episode. I have recently stuck with effexor because it makes me last longer in bed, basically giving me control of my ejaculation something that is nice to have, and well since I cant seem to do it with out effexor, I am not shy to say it works. Recently I am not in a relationship and have reduce my dosage by tiny amounts each few days . In one month I have dropped from 300 mg to 75 and noticed no negative side effects. I have yet to have sex but it is an expensive way to control your time of ejaculation. :)
 
drminaq said:
I have tried almost every antidepressant out there with the exception of MAOIs none have done a noticeable thing to me. With the exception with caused insomnia which led to a manic episode. I have recently stuck with effexor because it makes me last longer in bed, basically giving me control of my ejaculation something that is nice to have, and well since I cant seem to do it with out effexor, I am not shy to say it works. Recently I am not in a relationship and have reduce my dosage by tiny amounts each few days . In one month I have dropped from 300 mg to 75 and noticed no negative side effects. I have yet to have sex but it is an expensive way to control your time of ejaculation. :)
Click to expand...

I've been on effexor 75mg x2 a day for more than a week andit has taken away my sex drive basically, I'ts weird to never feel the urge to have sex or to not get turned on by a hot woman. Also the ejaculation reduced a lot in my case.
Did this happend to yoi as well?
 
This happened when I was on Paxil. It was almost impossible to cum. However, it only happened once I was moved from 40mg to 60mg.

This is the case with almost all SSRI's. Some people are prescribed low doses of an anti-depressant to sure premature ejaculation.
 
Well, a little update from me.

I went to my psych yesterday and we decided to up my Lexapro to 30mg (which is the highest he will go with this medication). I was having 'flat' moods and a cloud of depression, which is odd for me. Most of my problems almost always stem from anxiety and not depression.

We'll see how the 30mg of Lexapro works once it stables out. If not, I'll have to be switched to something else (once again! ugh!).

He also gave me atarax to take when my clonazepam isn't cutting it alone. My dr won't go over 2mg of benzos a day (which I think is the sign of a good dr). Also, I've started therapy, which I've been to twice so far. It may be a lot of work (the therapy) but I need it.
 
I have tried paxil, zoloft, wellbutrin, and effexor for my GAD. None of them helped, they just made me feel "duller". My doc won't prescribe me Klonopin anymore, but while I was on it it helped immensely.

i also started on Methadone a few weeks ago and these past few weeks I have felt more stable than I have in years.
 
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