I guess if you know you know...
Clonidine makes opioids work longer & better, benzos better, it makes barbiturates dangerous. It makes Z-drugs work better. Just because something does gets dubbed to have no "recreational effects" does not mean it is not working. I can tell a huge difference when I do not add it to my meds together.
It prevents pain signals transmissions to the brain and produces analgesia at pre-and post-alpha-adrenergic receptors in the spinal cord.
It is 40 times stronger than Xylazine mg per mg. If "Duraclon" was in the tranq-dope, about everyone would be dead.
Next time you meet a anesthesiologist ask them for Duraclon and watch their side eye pop up. Like this fool cannot handle that. Where did they even hear about it? We reserve that for cancer patients to add to their opioids when the opioids are not working to relief their pain. there is a reason Clonidine is used in epidurals.
The same reasons I take Clonidine with my opioids, Benzo, and Z-drug daily.