Opioids What do you find more enjoyable heroin or fentanyl?

[Dextro .45]

Once Diacetylmorphine (Heroin) rapidly metabolizes into 6-MAM the most beautiful profoundly euphoric rush, warmth and all physical & emotional pain melts away flawlessly…….

Diacetylmorphine (Heroin) + Cocaine (high purity) or Ritalin / Dexedrine / Adderall …..injected IV in same rig is a beautiful feeling……not to diminish its immensely valuable & legitimate pharmaceutical values for chronic pain, treatment resistant depression

WWII studies found adding a dopaminergic stimulant (d-Amphetamine/Dexedrine) to Morphine Sulphate SIGNIFICANTLY enhanced the analgesic painkilling properties of the Opioid. ….reduced sedation & enhamced mental function, mood-boosting properties, robust anxiolytic effects and enhanced vigilance and endurance/energy

Higher doses of the sedating opioid can be tolerated due to the potent dopaminergic stimulant…..both compounds complimented each other and had a robust synergetic effects …..increased dopamine & norepinephrine in the CNS has analgesic properties alone…..add a powerful Opioid narcotic like Oxycodone or Hydromorphone and you’re good to go

Add a IM injection of depo-Testosterone 200mg and you are like a super charged, confident, bolt, energetic, pro-social, enhanced strength & endurance and Significant mood-boosting effects, an Amazing antidepressant and pro-sexual atomic bomb lol….like solid STEEL, and the erotic desire to back it up ………I have a legit script for everything 10-15 years and it’s Soooooo effective and essential for the aging male 40+

Testosterone, aerobic exercise, healthy sexual activity……and the occasional oral Speedball when needed lol

Oxycodone IR
Ritalin or Dexedrine
Valium & Xanax
Pregabalin
Ethanol

All together + testosterone 200mg IM several days prior to reach peak serum levels

 

[paranoid android]

Neer had smack but fent is far less euphoric then morphine. diladid or even oxy

 

[Psynaught]

I've never tried heroin. In fact I had never been high on an opiod until about a year, year and a half ago. I have had many surgeries, most resulting from MMA relate injuries (full facial reconstruction, broken leg, shoulder) but only took what is prescribed as prescribed.

Then a while back I was getting real Oxy 3 mg (real powder in capsules made by a shady pharmacy, so it hit hard) and took 2 at once and WOW! Then I understood why everyone likes Oxy so much. Since then I get high on Oxy once a month, maybe twice tops.

I bought a bunch of fent by accident and it is terrible for getting high, Pain relief its great but the high is absolutely no fun at all.

 

[4DQSAR]

I have a hypothesis that opioids that have high affinity for the MOR tend to also have much longer 'receptor occupancy time' with M two to eight minutes compared to fourty five minutes to hours for fentanyl. So in essence it's not possible to produce a compound that is both highly potent and highly euphoric.

Every single example of a chemist involved in the production of potent opioids who went on to break rule 1 resulted in really bad outcomes in every single case. Suicide to what sounds like permanent alternation of the body of the user i.e. someone being in AWS over a YEAR after consuming the compound(s).

I also suggest that anything too potent for someone possibly already under the inflence to eyeball NEEDS to be in some form or reliable fixed-dose unit. Even then, I suspect that if you go much over x10M, it's a law of diminishing returns.

In the UK during the 70s both Diconal and Palfium were being overprescribed. I could not work out why compounds with only about 20% oral bioavailability were somehow being allowed. Then I discovered the official press release surrounding both of them. In them, right at the top, it states 'high oral bioavailability' i.e. the manufacturer knowingly lied,

For what it's worth, people in the US have told me oxymorphone or levorphanol were the MOST euphoric - and these people had tried a LOT of stuff. I find it interesting that both are around x10M and parentheral administration of the two synthetics mis-sold in the UK are x5-x15M in potency.

So yeah, MAYBE you can go a little higher (sic) but I suggest not much more.

 

[Bigsammy610]

Wasn't here also once a thread about a person who said he synthesized pharaoh fentanyl by himself and consumed way too much and had the worst withdrawal ever haha. I am still searching for that thread. But some people thought he would be trolling, but all the information he gave, made it sound like he wasn't. Because I read it like mid 2023 when I was withdrawaling from O-DSMT...kinda helped for not feeling alone going through withdrawal...the first withdrawal for me was totally unexpected and my first withdrawal ever and thought it was something else. Then I had later a second withdrawal and luckily that horrific experience helped me to stay away from any RC-Opioids since then and it will stay that way

I'm still trying to find that thread as well haha it was legendary

 

[noclipuser]

I like to dose Oxycodone, Methadone, Clonidine, Ativan, and Vistaril PAM at the same time. It is my B-52+

Lmao why the clonodine tho? All it does is decrease blood pressure and really has no recreational effects.

 

[Psynaught]

I have never done heroin, but the high from Oxy is 100 times better than fentanyl. Fent is just not that much fun.

 

[PenguinWithNapalm]

I’ve done a lot of both and I can say with confidence that heroin is better. I think there are very few people that would disagree. Fentanyl is way stronger but all you do is nod off and fall asleep with very little if any euphoria. Heroin is all euphoria

 

[Dextro .45]

Over 20 years ago I had a solid connection for H…..like, REAL Diacetylmorphine HCL (as real as it gets) before all that B.S. fentanyl parasitic filth infected the supply of Diamorphine

I know for a fact it was genuine Diacetylmorphine as I tested my urine privately at home and it tested positive for 6-MAM (the main active metabolite of H further metabolizing into Morphine)

It was a super fine, beach sand consistency of light tan beige powder with a pungent odour of vinegar (like opening a bag of salt & vinegar chips) ….due to Aceytic Anhydride the main compound pre-courser that reacts with Morphine base to synthesize Diacetylmorphine (Heroin) further reacted with concentrated hydrochloric acid to yield the water soluable hydrochloride salt……Diacetylmorphine Hydrochloride (Diamorphine) “Heroin”

Fentanyl is a fully synthetic mu-opioid agonist 100X more potent than Morphine but it’s cold commie trash

Oxycodone is #1 HANDS DOWN (most euphoric bliss I’ve ever experienced in my entire life)
Hydromorphone (Dilaudid) is Amazing in pharmaceutical vials for injection
Diacetylmorphine (Diamorphine) the TRUE Gold Standard of Euphoric opioid analgesics
Methadone (Dolophine) fully synthetic Potent full mu-agonist with long half life (and euphoric yes)

Ritalin (Methylphenidate)
Preludin (Phenmetrazine)
Cocaine (illicit)
Amphetamine (Benzedrine)
D-Amphetamine (Dexedrine)
D-Methamphetamine (Desoxyn / Methedrine)
Biphetamine (1950’s Adderall)
Benzphetamine (pro-drug to d-Meth then into d-Amph)
Dexamyl (d-Amp + Barbiturate)
Desbutal (d-Meth + Barbiturate)

Diazepam (Valium) - Best Anxiolytic & muscle relaxant benzodiazepine
Alprazolam (Xanax) - rapid anxiolytic & antidepressant
Lorazepam (Ativan) - Anxiolytic & sedative
Clonazepam (Klonopin) - anticonvulsant, sedative & anxiolytic
Etizolam & Deschloroetizolam - Euphoric/Antidepressant/mood-boosting effects
Diclazepam (2-Chloro Diazepam) > Delorazepam >> Lorazepam (Ativan)
Avizafone (Pro-Diazepam) water soluble, RAPID acting pro-drug metabolizes into Diazepam

Pregabalin (Lyrica) - potent anxiolytic & anticonvulsant
Clonidine - VERY effective anxiolytic & sedative (lowers BP & HR)
Cannabis - Indica & Sativa
LSD-25 - 100ug standard tab
Psilocybin
Ketamine - Disassociate anesthetic, antidepressant, analgesic
GHB
HGH
Testosterone
Nicotine
Caffeine
Ethanol

A lifetime supply of every single CII controlled substance and other compound’s listed…..in a secured dark, dry, VERY cold cellar storage unit in hidden basement location.

Each compound in a pharmaceutical industrial 100kg (220 lbs) blue plastic drum 4/per pallet in secure cellar ….next to my underground indoor shooting range with proper ventilation 50/100/150 yards sound proof, next to my bank style fireproof vault with all my hi-end toyz

 

[TheUltimateFixx]

How is this even a question.

 

[F.U.B.A.R.]

Over 20 years ago I had a solid connection for H…..like, REAL Diacetylmorphine HCL (as real as it gets) before all that B.S. fentanyl parasitic filth infected the supply of Diamorphine

I know for a fact it was genuine Diacetylmorphine as I tested my urine privately at home and it tested positive for 6-MAM (the main active metabolite of H further metabolizing into Morphine)

It was a super fine, beach sand consistency of light tan beige powder with a pungent odour of vinegar (like opening a bag of salt & vinegar chips) ….due to Aceytic Anhydride the main compound pre-courser that reacts with Morphine base to synthesis Diacetylmorphine (Heroin) further reacted with concentrated hydrochloric acid to yield the water soluable hydrochloride salt……Diacetylmorphine Hydrochloride (Diamorphine) “Heroin”

Fentanyl is a fully synthetic mu-opioid agonist 100X more potent than Morphine but it’s cold commie trash

Oxycodone is #1 HANDS DOWN (most euphoric bliss I’ve ever experienced in my entire life)
Hydromorphone (Dilaudid) is Amazing in pharmaceutical vials for injection
Diacetylmorphine (Diamorphine) the TRUE Gold Standard of Euphoric opioid analgesics
Methadone (Dolophine) fully synthetic Potent full mu-agonist with long half life (and euphoric yes)

Ritalin (Methylphenidate)
Preludin (Phenmetrazine)
Cocaine (illicit)
Amphetamine (Benzedrine)
D-Amphetamine (Dexedrine)
D-Methamphetamine (Desoxyn / Methedrine)
Biphetamine (1950’s Adderall)
Benzphetamine (pro-drug to d-Meth then into d-Amph)
Dexamyl (d-Amp + Barbiturate)
Desbutal (d-Meth + Barbiturate)

Diazepam (Valium) - Best Anxiolytic & muscle relaxant benzodiazepine
Alprazolam (Xanax) - rapid anxiolytic & antidepressant
Lorazepam (Ativan) - Anxiolytic & sedative
Clonazepam (Klonopin) - anticonvulsant, sedative & anxiolytic
Etizolam & Deschloroetizolam - Euphoric/Antidepressant/mood-boosting effects
Diclazepam (2-Chloro Diazepam) > Delorazepam >> Lorazepam (Ativan)
Avizafone (Pro-Diazepam) water soluble, RAPID acting pro-drug metabolizes into Diazepam

Pregabalin (Lyrica) - potent anxiolytic & anticonvulsant
Clonidine - VERY effective anxiolytic & sedative (lowers BP & HR)
Cannabis - Indica & Sativa
LSD-25 - 100ug standard tab
Psilocybin
Ketamine - Disassociate anesthetic, antidepressant, analgesic
GHB
HGH
Testosterone
Nicotine
Caffeine
Ethanol

A lifetime supply of every single CII controlled substance and other compound’s listed…..in a secured dark, dry, VERY cold cellar storage unit in hidden basement location.

Each compound in a pharmaceutical industrial 100kg (220 lbs) blue plastic drum 4/per pallet in secure cellar ….next to my underground indoor shooting range with proper ventilation 50/100/150 yards sound proof, next to my bank style fireproof vault with all my hi-end toyz

You've obviously got more money than sense...

(Just fuckin jealous)

 

[Dextro .45]

Yes, maybe so….its just EXTREMELY comforting knowing I have an ample supply of everything. It’s very comforting knowing it’s there for a rainy day or when needed for emergencies

 

[hellinabucket77]

There is very little information on the effects of carfentanil in man. It appears to demonstrate a two-phase dose-response curve in man. Now that could be good or bad. If it means after a certain point increasing the dose does less, that's safer, but equally, if it means after a certain point increasing the dose does MORE, that's an issue.

But we haven't witnessed a disproportionate number of deaths associated with carfentanil, so is it'Ids TI higher than fentanyl?
But however you slice it, when something is > x30000 M in potency - it's a WMD if used as such.

I don't agree with the wmd on carfetty but I like where your heart is at. On the other hand, I think xylazine should be consider a wmd. It takes body parts off and kills so easily and is garbage. I don't know how it is technically legal in the States. I wish they would just legalize stuff already and people could start doing H again who really needed it. I would go back to H in a heart beat and even pay a premium for high purity straight H. Now in the States at least on the east coast... Its all Fetty or Fetty with xylazine. Its sad, it gives opioids a bad name / worse than they already got. I am sure you agree but people are in pain / those already heavily addicted need them. The Stats show how 90 something % of people go back to using and some people just cant stop and imo that's ok. Its life. incarceration or switching to things that will kill them is not the answer. Cheap safe legal supply is the only answer imo. Sorry for the soap box but I hope more people can see where I am coming from. I think if enough people complained to there people about xylazine then it would be taken out. I doubt it will ever go back to H in the States or Canada due to the way they can produce them without a plant and I have heard / researched that its pretty easy to make with the right chems and less product to move. I see where you are coming from and just wish it never got to that point. Well here is to wishing.

 

[Them Witches]

Lmao why the clonodine tho? All it does is decrease blood pressure and really has no recreational effects.

I guess if you know you know...

Clonidine makes opioids work longer & better, benzos better, it makes barbiturates dangerous. It makes Z-drugs work better. Just because something does gets dubbed to have no "recreational effects" does not mean it is not working. I can tell a huge difference when I do not add it to my meds together.

It prevents pain signals transmissions to the brain and produces analgesia at pre-and post-alpha-adrenergic receptors in the spinal cord.
It is 40 times stronger than Xylazine mg per mg. If "Duraclon" was in the tranq-dope, about everyone would be dead.

Next time you meet a anesthesiologist ask them for Duraclon and watch their side eye pop up. Like this fool cannot handle that. Where did they even hear about it? We reserve that for cancer patients to add to their opioids when the opioids are not working to relief their pain. there is a reason Clonidine is used in epidurals.

The same reasons I take Clonidine with my opioids, Benzo, and Z-drug daily.

 

[4DQSAR]

I don't agree with the wmd on carfetty but I like where your heart is at. On the other hand, I think xylazine should be consider a wmd. It takes body parts off and kills so easily and is garbage. I don't know how it is technically legal in the States. I wish they would just legalize stuff already and people could start doing H again who really needed it. I would go back to H in a heart beat and even pay a premium for high purity straight H. Now in the States at least on the east coast... Its all Fetty or Fetty with xylazine. Its sad, it gives opioids a bad name / worse than they already got. I am sure you agree but people are in pain / those already heavily addicted need them. The Stats show how 90 something % of people go back to using and some people just cant stop and imo that's ok. Its life. incarceration or switching to things that will kill them is not the answer. Cheap safe legal supply is the only answer imo. Sorry for the soap box but I hope more people can see where I am coming from. I think if enough people complained to there people about xylazine then it would be taken out. I doubt it will ever go back to H in the States or Canada due to the way they can produce them without a plant and I have heard / researched that its pretty easy to make with the right chems and less product to move. I see where you are coming from and just wish it never got to that point. Well here is to wishing.

It's not so important what I think - it's more that I foresee that such compounds will become listed in the CWC. After all, the VDV used some manner of fentanyl derivative in the Moscot Theatre Seige and it killed a lot of totally innocent people.

I've actually posted a thread on various institutions who are already saying such compounds should be listed and their voice is far more important than mine.

When you realize that H sells for $2000/Kg in Afghanistan, you realize that legal control is funding criminals and terrorists. The majority of the poppy grown to produce morphine and diamoprone (Heroin) as well as the direct precursors for oxycodone and oxymorphone come from Tazmania. It's possibly a good idea since it's reasonably secure given how remote the place is.

But as it stands, Grisham's law will always result in the most profitable (read potent) drug being cheaper on a per-dose basis and thus the one that will eventally take over the market.

I think that is the thing governments SHOULD consider. The 'war on drugs' has been fought and lost, pragmatic response is to make it all legal so people can choose. Hard to know how much a gram of pur H would cost but I would be surprised it it was more than £10 after tax and duty.¬

BTW Obviously intoxicated people should not be driving or operating heavy machinery. I don't think putting others in harms way is a right or a freedome.

 

[Zopiclone bandit]

I hate fentanyl in comparison to heroin. It's physically stronger, but is cold and mechanical. It lacks the godlike euphoric warm hug that heroin provides.

I actually think it's tragic that there is a whole generation of junkies who have never even tried real heroin because fent is all they know.

THIS 100%

 

[paranoid android]

Never had smack but fent sucks even compared to codeine imo. Dilaudid and morphine are much better. Fent just does not have any euphoria at all. I actually found it dysphoric

 

[Them Witches]

Never had smack but fent sucks even compared to codeine imo. Dilaudid and morphine are much better. Fent just does not have any euphoria at all. I actually found it dysphoric

I am not a fan of Fentanyl in any form this includes buccal 1600mcg lollipops (equals to 209mme) and the Fentanyl 100mcg IV (equals to 10mg morphine IV). It sucks for pain and wears off too quick. Including myself, most opioid tolerant patients find Fentanyl to feel like a stimulant. The initial pain relief lasts for 5 minutes. No nodding off and sedated like diamorphine, Diluadid, or Oxymorphone. After the first dosage it is like chasing something that will never happen. Diluadid, diamorphine, Oxymorphone IV is so much better for pain, sedation, and "euphoria."

My last surgery they offered Fentanyl 100mcg IV every 4hrs for acute post-op pain. I said no and had my PCP handle the PCA. The order was :
-- Diluadid 4mg every 4hrs for 36hrs, then 2mg every 4hrs PRN
-- Droperidol 2.5mg IV every 8hrs for 24hrs
-- Haldol 5mg every 8hrs for 24hrs
{ I love Droperidol and Haldol mix with pain meds for post-op acute pain, discomfort, and agitation. Droperidol is bad-ass IMO }

I was in the hospital for 9 days and they kept the Diluadid 2mg every 4hrs PRN until the 7th day. They reduced it to 1mg every 4hrs for the last 2 days then Rx'd Hydromorphone 2mg PO tablets for 3 days. Of course I would have loved more but I already had a PO 435mme daily from Roxicodone and Methadone before the surgery and when I left the hospital.

If feel they did me right increasing my MME by 480 for 36hrs, then 240mme for 6.5 days, then 120mme for 2 days. then the PO tablets for 3 days. It took 2-3 days for my normal PO pain meds to feel balanced out again. If it were not for my daily PO Clonidine, Ativan, Cyclobenzprine, and Vistaril PAM, the MME change would have lingered longer to feel normal again.

==================================================================================

This is why I do not want Fentanyl IV :

The total daily Morphine Milligram Equivalent (MME) for hydromorphone 2 mg IV injection every 4 hours is 240 MME/day PO Morphine.
The 10 mg intravenous (IV) dose of morphine is equivalent to a 30 mg oral (PO) morphine milligram equivalent (MME)
A total daily dose of 60 mg of intravenous (IV) morphine in 24 hours is equivalent to 180 milligrams of oral morphine (MME) per 24 hours

The only half way decent Fentanyl dose if letting a 100mcg (16.4mg) Sandoz patch dissolve in the buccal.

 

[KetWise]

Question is funny

Its like asking if you prefer ketamine or xylazine ?

I never had fentanyl . ive seeen it only once it my life. I went to the border of india and pakistan a decade ago. So close to the source. I've smoked actual brown sugar at 85 percent one dragon a point in the foil you would nod for 6 hours head in the foil. It's too good. points going for 5 dollars lasting you the day... and rthey were overcharging us
back in europe "brown" cut down to 5 percent people uying grams at 30 euros adn doing multiple grams a day... nonsense .
I tried to IV it with cooked with acid I would need 0,6g to have a half decent hit... wtf is that .. better shoooting morphine. but good heroin is still better

I relapsed few years ago went to score beige tiny very hard points 4 of them it must be half points, 3 euros for one. I cried. it wsa that good .4 days in a bliss . only snorted I cant even. imagine injecting this. but i am in another world now

fuck fent

 

[PenguinWithNapalm]

Question is funny

Its like asking if you prefer ketamine or xylazine ?

I never had fentanyl . ive seeen it only once it my life. I went to the border of india and pakistan a decade ago. So close to the source. I've smoked actual brown sugar at 85 percent one dragon a point in the foil you would nod for 6 hours head in the foil. It's too good. points going for 5 dollars lasting you the day... and rthey were overcharging us
back in europe "brown" cut down to 5 percent people uying grams at 30 euros adn doing multiple grams a day... nonsense .
I tried to IV it with cooked with acid I would need 0,6g to have a half decent hit... wtf is that .. better shoooting morphine. but good heroin is still better

I relapsed few years ago went to score beige tiny very hard points 4 of them it must be half points, 3 euros for one. I cried. it wsa that good .4 days in a bliss . only snorted I cant even. imagine injecting this. but i am in another world now

fuck fent

Amen to that. God I’d love to try that.