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Tributylamine

sarbanes

Bluelighter
Joined
Mar 8, 2007
Messages
481
Is listed in Merck Index as being CNS stimulant (not Thera Cat, but as a side effect I believe). Is it generally true that almost any bulky enough group attached to a simple, primary amine, might have stimulant properties?
 
sarbanes said:
Is listed in Merck Index as being CNS stimulant (not Thera Cat, but as a side effect I believe). Is it generally true that almost any bulky enough group attached to a simple, primary amine, might have stimulant properties?
would expect this to be a cholinergic like tetramethylammonium compounds which do have some cns stim effects shortly before killing you.
 
vecktor said:
would expect this to be a cholinergic like tetramethylammonium compounds which do have some cns stim effects shortly before killing you.

but....u only live once! heheh;) no seriously, we're not talking about quats here, lol.
 
sarbanes said:
but....u only live once! heheh;) no seriously, we're not talking about quats here, lol.

do you mean tert butyl amine rather than tetra?
 
vecktor said:
do you mean tert butyl amine rather than tetra?


nuno, not tertiary, but I was off by (1) methyl group. It is tributylamine "Caution: Causes CNS stimulation, skin irritation, sensitization." But of course would convert it to a salt!
 
sarbanes said:
nuno, not tertiary, but I was off by (1) methyl group. It is tributylamine "Caution: Causes CNS stimulation, skin irritation, sensitization." But of course would convert it to a salt!

Err, I meant to say I was off my one butyl group!:\
 
So it's the tertiary amine formed by substituting butyl groups into ammonia (tetrabutylamine implies a quaternary amine and that isn't going to get past the BBB). Looks like it might act via cholinergic mechanisms a la arecoline.

Ah right I've looked at the link. Thing is that MSDS says nothing about CNS stimulation
 
fastandbulbous said:
So it's the tertiary amine formed by substituting butyl groups into ammonia (tetrabutylamine implies a quaternary amine and that isn't going to get past the BBB). Looks like it might act via cholinergic mechanisms a la arecoline.

Ah right I've looked at the link. Thing is that MSDS says nothing about CNS stimulation

Its tri (not tetra, just in case you didn't see my correction). And yeah, the ref. to CNS stim. was in the "Merck Index" - NOT in the MSDS.
 
sarbanes said:
Its tri (not tetra, just in case you didn't see my correction). And yeah, the ref. to CNS stim. was in the "Merck Index" - NOT in the MSDS.
These guys are trying to answer YOUR questions, So LOOSE, the ATTITUDE!!!
 
jah said:
These guys are trying to answer YOUR questions, So LOOSE, the ATTITUDE!!!

Want to become an ex-bluelighter? No out and out insults or thats the result
 
Last edited by a moderator:
sarbanes said:
Want to become an ex-bluelighter? No out and out insults or thats the result

i bet you live 4 moments like that =D in fact, I wouldn't be surprised if you banned me as a result of your anger at this post. Still, I will abide by the rules, and I think you, as a mod, should follow the spirit of those rules as well (although I hear you've been given wide discression), and not ban a productive member on his 1st day, even if my lack of respect for you gets you pissed. I know, your just doing yer job!
 
Because you are a 1st offender, you get the obilgatory don't do it again edit. I do follow the spirit of those rules - where in this forum have I said anything in the spirit of your post that I edited. Productive or not, if you indulge in out & out insults, action has to be taken (see the BLUA). I actually let a lot of things go by in this forum that strictly I should be issuing warnings for but I'd rather just edit and advise people not to do it again.

If you have any issues with my actions, either PM me or one of the admin staff if you think I've been unfair. This forum is not the place for any complaints about my moderation
 
fastandbulbous said:
Because you are a 1st offender, you get the obilgatory don't do it again edit. I do follow the spirit of those rules - where in this forum have I said anything in the spirit of your post that I edited. Productive or not, if you indulge in out & out insults, action has to be taken (see the BLUA). I actually let a lot of things go by in this forum that strictly I should be issuing warnings for but I'd rather just edit and advise people not to do it again.

If you have any issues with my actions, either PM me or one of the admin staff if you think I've been unfair. This forum is not the place for any complaints about my moderation[/QUOTE
I understand, and thanks for putting up with this (you shouldn't have to). Tomorrow is a new day, and I will try & better myself.
 
sarbanes said:
fastandbulbous said:
Because you are a 1st offender, you get the obilgatory don't do it again edit. I do follow the spirit of those rules - where in this forum have I said anything in the spirit of your post that I edited. Productive or not, if you indulge in out & out insults, action has to be taken (see the BLUA). I actually let a lot of things go by in this forum that strictly I should be issuing warnings for but I'd rather just edit and advise people not to do it again.

If you have any issues with my actions, either PM me or one of the admin staff if you think I've been unfair. This forum is not the place for any complaints about my moderation[/QUOTE
I understand, and thanks for putting up with this (you shouldn't have to). Tomorrow is a new day, and I will try & better myself.

Oops, sry did't mean to quote you as being me, very sorry. BTW, what'cha think of my avatar!
 
MattPsy said:
The Hive logo... your point?

I think its been made abundently clear that this is not the proper forum for unhappy individuals with which to vent their tude. If your want a fight, go elsewhere - you aren't wanted here if all your going to do is make snide comments :( No offence, BTW.
 
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