• Welcome Guest

    Forum Guidelines Bluelight Rules
    Fun 💃 Threads Overdosed? Click
    D R U G   C U L T U R E

Tramadol vs Oxycodone

Borax said:
if your not a dopehead/pain pill addict, which im assuming you are (; with an insane tolerance, you will feel tramadol and I challenge you to find evidence against that
Click to expand...
am totally clean from opioids now and have zero dependency after having kicked 6 weeks ago.

Tried some tramadol just to see what it was like clean.

Tramadol is still shit.

Tramadol was the first “opioid” that I ever tried. It was shit and did absolutely nothing to my pain scores. This was before I ever tried a traditional opioid.

It fucks you up and makes you dizzy but it’s analgesic effect it garbage.
 
The choice of tramadol and oxycodone is based on specific pain management needs, patient medical history, and potential risk factors, tramadol is often chosen for moderate pain with no potential for abuse, while oxycodone is offered reserve more severe pain due to its greater power.
 
Just to reply to the initial question: I also have nothing to discuss here: Tramadol is what I can, while oxy is what I can't get. And as it works perfectly fine for me the Tramadol choice is easy 🤷
 
I have experienced tramadol nod as more hypnotic and sterile, oxycodone is more like a cloud in which you travel and occasionally drop off.

Of course if you are not optimal metabolizer like me or have great tolerance, oxycodone is better for deep end nod.

For some reason I btw also don't seem to metabolize oxy very fast; people say it doesn't last long, but in my experience, the high lasts whole day.

Goes to prove saying; you mileage may vary
 
But really peak of oxy high is golden standard of nods in my books. But tramadol is not bad really and it has some interesting properties.

I have smoked a tiny bit of heroin and god damn if I'd do it more I would probably consider that the golden standard, it gave me vibes that if I would get properly high on it few times...well, I am afraid to think about it, honestly. I have never been administered morphine by medical professionals either.

But yea, best moments with oxy can not be really matched with tramadol, at least with my body chemistry.
 
LucidSDreamr said:
am totally clean from opioids now and have zero dependency after having kicked 6 weeks ago.

Tried some tramadol just to see what it was like clean.

Tramadol is still shit.

Tramadol was the first “opioid” that I ever tried. It was shit and did absolutely nothing to my pain scores. This was before I ever tried a traditional opioid.

It fucks you up and makes you dizzy but it’s analgesic effect it garbage.
Click to expand...
I have taken massive doses of morphine pills also tramadol. I was surprised by how strong and pleasant the high was from tramadol and it made me extremely horny which is the effect I'm usually going for on drugs so I mean honestly to me I liked tramadol better. But then years later I stole tramadol from my ex-husband and got little effect from it so I was like confused at that point the bottle said tramadol clearly so maybe it was a bad batch from mexico (where my friends get it all from)??!?
 
paranoid android said:
There is no comparison. While oxy is hardly my first choice in opiates it is miles better for pain relief and getting high then tram ever could be.
Click to expand...
I can dose 400mg oxy and my pain would be better treated by 1500mg tramadol 🤷 But with so much tramadol i need benzos + levetiracetam to not have seizures but really, except hydromorphone high dose and dihydrocodeine high dose, tramadol in junkie doses is best for my pain. Probably because i have chronic, post-acute and also neuropatic pain.
 
Hello.
I read whole WHO documents about tramadol, oxycodone, metabolites and many research that provided this rusults:

Tramadol is low potency MOR agonist with Ki = 2400nM.
However, if u are able to metabolize tramadol into O-DSMT (by cyp2d6),
most of metabolizers convert 15-20% of ingested tramadol into O-DSMT which is full MOR agonist with Ki = 11 nM.

Oxycodone is MOR agonist with Ki = 18 nM.

This means, tramadol ( metabolized into O-DSMT) is even more potent than oxycodone and this combined with it's longer duration of action, added monoaminergic properties can be the cause of tramadols horrible withdrawal symptoms.
Also, even less than 50mg (37,5mg) , sometimes cause vomiting for new users due to rapid raise in serotonine.

The only reason they marketed tramadol as much less addictive, is longer time to take effects = no rush. This is because metabolizing tramadol into O-DSMT take some time but in form of oral drops, i feel it in 30 minutes. In IR tablets in 1 hour.
But many, many years ago they knew this is potent synthetic opioid with SNRI and other added properties.


Just little bit of i formation.
Be safe and and have a nice day.
 
emkee_reinvented said:
She neither was outright aggresive. more like ice cold steel. Passive aggresion she allready had, just like her Mother, but it seemed to agrevate it.

I totally dislike it while Kratom is a nice semi opiod.
Click to expand...
When i started using tramadol, i was passive-agressive to the point i won every argument and due to this my brother hates me. Now it makes me much more emphatic, social and psychologicaly warm. It also gives me massive energy almost on par with amphetamine but it's 11 years after i started and i take massive doses. It also works for my pain better than any other opioid except hydromorphone.
 
LucidSDreamr said:
am totally clean from opioids now and have zero dependency after having kicked 6 weeks ago.

Tried some tramadol just to see what it was like clean.

Tramadol is still shit.

Tramadol was the first “opioid” that I ever tried. It was shit and did absolutely nothing to my pain scores. This was before I ever tried a traditional opioid.

It fucks you up and makes you dizzy but it’s analgesic effect it garbage.
Click to expand...
I did many opiates and opioids but for my pain, high dose of tramadol works the best.
Probably due to myself being fast cyp2d6 metabolizer ( a lot of potent MOR agonist O-DSMT produced in my body) and due to it's effects on serotonine and noradrenaline. But i have to take something to prevent seizures when i use it.
 
Tramadol i ll pass. Ok get it o-DSMT is the heavy-est Opiod i used.
Ime they are nothing alike. Bad metabolyzer or just hate the neuro-chemical warfare Tramadol causes

Codeine is fun hell might a doc give me Oxycodone a 2-nd time, i ll at least once abuse it.
Kratom as temporarly a legal alternative beats Tramadol ime. But they are trying to illegalize it, so.
 
Last edited:
WellTram said:
When i started using tramadol, i was passive-agressive to the point i won every argument and due to this my brother hates me. Now it makes me much more emphatic, social and psychologicaly warm. It also gives me massive energy almost on par with amphetamine but it's 11 years after i started and i take massive doses. It also works for my pain better than any other opioid except hydromorphone.
Click to expand...
Wow. That's interesting 🤔. Might explain why I became a shouting mess for quite a while on it. And nowadays I'm seriously better with it...
Edit: I was wrong. Still getting those irritable phases 😑
 
Last edited:
emkee_reinvented said:
Codeine is fun hell might a doc give me Oxycodone a 2-nd time, i ll at least once abuse it.
Kratom as temporarly a legal alternative beats Tramadol ime. But they are trying to illegalize it, so.
Click to expand...
Agree on Codein, but Kratom is so damn short lasting it's pissing me off - doesn't mean I'm not using it sometimes 😅
 
emkee_reinvented said:
Tramadol i ll pass. Ok get it o-DSMT is the heavy-est Opiod i used.
Ime they are nothing alike. Bad metabolyzer or just hate the neuro-chemical warfare Tramadol causes

Codeine is fun hell might a doc give me Oxycodone a 2-nd time, i ll at least once abuse it.
Kratom as temporarly a legal alternative beats Tramadol ime. But they are trying to illegalize it, so.
Click to expand...
If u feel codeine, than your problem with tramadol is immediate reuptake inhibition of serotonine and noradrenaline combined with serotonine release ( not like ssris, tramadol do it like ssris but also as for example meth or mdma, direct release of serotonine.
It also raise dopamine but this is probably done by codeine, too.
The problem Is, Its monoaminergic properties are immediate, like instant antidepressive SNRI + serotonine releaser. I believe that noradrenaline reuptake inhibition Is less harsh to handle than Its superfast ssri and serotonine release actions. In this aspect it Is very simmilar to methamphetamine ( IT Is reuptake inhibitor but also monoaminergic releaser ). And Its potent, results showed that normal safe dose Od tramadol cause almost 80% increase in serotonine which Is simmilar to many antidepressive medications. But for me, vortioxetine which raise dopamine, noradrenaline, serotonine but only to around 50-60 % works much better and doesn't lost it's effects like for example citalopram.
 
You must log in or register to reply here.
Top