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Opioids Tianeptine Megathread v1

Crunkazcanbe- I have the white scoop and then the blue 12mg scoop that came with my order what do you think a good scoop and maybe half scoop using the white 90mg scoop for my first time and how long does it take for effects to kick in usually
 
Crunkazcanbe- I have the white scoop and then the blue 12mg scoop that came with my order what do you think a good scoop and maybe half scoop using the white 90mg scoop for my first time and how long does it take for effects to kick in usually

The white scoop is about 100mg is what my scale shows . Do about 100 mg for your first time ,but if you have a slight opiate tolerance I recommend 130-200mg for first time . To have a pretty good nod . :)

I have a shit ton of the blue and white scoops I get 50-60 Grams a month.

Half of the white scoop will do nothing but disappoint you I promise. Trust me at least a whole white scoop kinda heaping will give a good buzz .
 
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I done 2 scoops over an hour ago nothing major but I ate dinner maybe 20 minutes after dosing I just tried 2 more scoops I have a mild buzz but nothing crazy it's only been like five minutes or so any advice and also how long does it take to kick in good I may try the vaping idea also will grape juice potienate it like with standard opiates
 
I done 2 scoops over an hour ago nothing major but I ate dinner maybe 20 minutes after dosing I just tried 2 more scoops I have a mild buzz but nothing crazy it's only been like five minutes or so any advice and also how long does it take to kick in good I may try the vaping idea also will grape juice potienate it like with standard opiates

Takes about 30mins to start working for me man. It would be wise to get a scale man to se exactly how much your taking, but with my high tolerance with opiates I do a whole lot . 5-6 heaping white scoops. Thats just me though . It takes about 30 mins to kick in though give it at least that then take another heaping white scoop . Its funny but the only thing been found to potienate Tianeptine is salicylic acid aka asprin take a gram or so of asprin with it .


EDIT: What ever you do man do not give up on it. I gave up on it the first time of getting this ;because I could not find my sweet spot. Thats all it is you have to find your sweet spot . For you it may be like me over 250mg . :) Just keep trying it ,and I promise you you will find your sweet spot. Tolerance builds quick to so watch out for that , and when you see your self getting over 500 mg in 1 single dose back it back down to lower your tolerance otherwise this will turn into a very expensive habit .
 
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has anyone here thought of getting the sulfate form of tianeptine as opposed to the sodium salt.

its less hygroscopic so its easier to store and encapsulate.

also i think its half life is longer and it is absorbed more slowly into the bloodstream, so instead of dosing 3x a day, 1x a day is enough. i think i read that you might just need 25mg as opposed to 12.5mg

Intresting.... I have never looked into any differents forms of tianeptine but I did read about a popular amazon vendor selling a a form other than the sodium on their web site that was pretty much useless. Regarding stomach pains, I definitely feel it in my gut when taking ~150 several times through out the day.
 
I always worry that they are going to schedule anything people talk about. Especially when people post about "nodding out" and how it's "like X drug." TMI TMI

I wonder how dangerous it is for you who are taking 300-500mg at a time.

The simple fact is there are bad people who don't want ANY manoaminergic drugs (IE abuse potential) available legally. They want people to get locked up. The slave trade is a HUGE industry and it is mainly fueled by the "war on drugs" (war on people). These are the kinds of people to talk about Jesus and God's Word for the sake of personal gain. These are the kinds of people who get paid from the slave trade (mass imprisonment of non-violent drug law offenders, with them working in factories for virtually nothing, and truly nothing with phone calls considered, making things that would pay good money on the outside) and/or politics. I, for one, will not possess anything that is illegal. Not because I think I would get caught, but because I actually believe in God's Word unlike the extremely rich Nazi-like slave traders who hold stocks in companies like Viacom and CCA at the same time while using their ill-gotten gains to influence legislation. And as a result of believing in what they claim to believe in, I can not break the law. I wish people would just hush up about the legal things. I need manoaminergics for therapeutic purposes and I don't want to use research chemicals or be at the mercy of a doctor. Plus I hate the slave trade.

When people see posts comparing it to "insert X drug here" that has been sensationalized in the news, freedom is threatened.

I don't want to be harsh with my words, but this is one of the worst threads about tianeptine I have seen from a freedom-promoting point of view. Once they get done with kratom, they will continue down the list. Asprin and alcohol are far more dangerous to the public, but they will do it because "what about the kids?" More like "I get paid off of slavery."

To make it even worse, the slave traders are robbing the whole country. They make TONS of money off the slavery because the labor is virtually free, while the tax-payers pay for the housing, food, and medical care of the slaves. As you can see, it is right to be concerned that they will look to ban every last substance with real therapeutic potential (most of the best therapeutic drugs have abuse potential). It's not paranoid to think this. They are the kinds of people to look to control every aspect of your life, claim they believe in Jesus (BUSH! That liar didn't believe the Gospel AT ALL when he was in office), purchase yachts and mansions and private jets - and do it all while over 22,000 kids are dying every day from hunger and thirst. Trust me, it is not paranoid to think that they want to enslave people via the war on drugs, and they do not care how many people who need manoaminergics for therapeutic purposes are affected. I don't have anything against you abusing it in your own house as long as you don't drive, AND NEITHER DO THEY. They have a problem with your FREEDOM.

Anyone know if taking 300-500mg per day is hepotoxic in itself? I have to take 100mg or more at a time for therapeutic effects (treating akathisia with it)

I wouldn't be against this thread being removed!
 
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I always worry that they are going to schedule anything people talk about. Especially when people post about "nodding out" and how it's "like X drug." TMI TMI

I wonder how dangerous it is for you who are taking 300-500mg at a time.

The simple fact is there are bad people who don't want ANY manoaminergic drugs (IE abuse potential) available legally. They want people to get locked up. The slave trade is a HUGE industry and it is mainly fueled by the "war on drugs" (war on people). These are the kinds of people to talk about Jesus and God's Word for the sake of personal gain. These are the kinds of people who get paid from the slave trade (mass imprisonment of non-violent drug law offenders, with them working in factories for virtually nothing, and truly nothing with phone calls considered, making things that would pay good money on the outside) and/or politics. I, for one, will not possess anything that is illegal. Not because I think I would get caught, but because I actually believe in God's Word unlike the extremely rich Nazi-like slave traders who hold stocks in companies like Viacom and CCA at the same time while using their ill-gotten gains to influence legislation. And as a result of believing in what they claim to believe in, I can not break the law. I wish people would just hush up about the legal things. I need manoaminergics for therapeutic purposes and I don't want to use research chemicals or be at the mercy of a doctor. Plus I hate the slave trade.

When people see posts comparing it to "insert X drug here" that has been sensationalized in the news, freedom is threatened.

I don't want to be harsh with my words, but this is one of the worst threads about tianeptine I have seen from a freedom-promoting point of view.

Anyone know if taking 300-500mg per day is hepotoxic in itself?


Studies have shown it to only be hepotoxic in doses exceeding 4000mg in a single dose . Read here, and here. I am glad your worried though .


EDIT: Also I was not doing 400-500mg a day I was doing 500mg 3x a day . I have for the last few days been slowly backing my dose back down though due to tolerance ,and needing a huge amount to feel it anymore . I would not be against this thread being removed myself man. I see where you come from ,but since the thread was made I just thought I would put some honest info about the drug out there from my point of view about it .
 
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Studies have shown it to only be hepotoxic in doses exceeding 4000mg in a single dose . Read here, and here. I am glad your worried though .


EDIT: Also I was not doing 400-500mg a day I was doing 500mg 3x a day . I have for the last few days been slowly backing my dose back down though due to tolerance ,and needing a huge amount to feel it anymore . I would not be against this thread being removed myself man. I see where you come from ,but since the thread was made I just thought I would put some honest info about the drug out there from my point of view about it .

Oh it's not just u. It's the whole thread! And I have never seen one this bad. Not on reddit or otherwise.

I think you would benefit from a decent break. I am PMing u a suggestion.

I take around 100-150 mg and it treats akathisia. This is important because there are almost no legal drugs that treat akathisia. Akathisia is so bad that many people kill themselves from it. However, mine will only be there for a few more months. The closest thing they have outside of this or etizolam is benadryl - useless.

Yeah, I often just hope they stop legislating slavery. I'm not saying ALL drugs should be legal. But there should be a selection of legally available manoaminergics, and if people keep talking about them - there won't be any more outside of research chemicals which are dangerous. I doubt they will stop because of how much money is in slavery (they make a killing on slavery at CCA and they help brainwash inner city kids over at Viacom. U know, the "elite" are evil enough to put 2+2 together) along with Big Pharma/health insurance.
 
Is this any more socially motivating than kratom? because i take kratom twice a week and it helps with depression alot but doesnt move me to socialise which is the root of my depression (isolation and general mysanthropy). I want something mild that will move me to socialise.

Also is it any more psychologically addicitve than kratom? I have no probs with twice a week use of kratom. Im tlkaing about therapeutuc doses not the wreckless doses you guys are taking.
 
it isn't going to turn you into a social butterfly, but it will help to noticeably reduce social anxiety for up to 3 hours after ingestion. i have found that because you know after taking it that being in social situations won't be as awkward, i feel more confident in my ability to be around other people.

it isn't psychologically addictive at all (at 12.5mg). another poster using therapeutic dosage ranges uses it for 2 weeks, then does 2 weeks off and cycles it that way, so that tolerance doesn't build up
 
Hmm well kratom does that for me already. Does it not offer anything over kratom in the social front then? I won't bother if not cos Im alot more comfortable taking kratom semi regularly than this, but if it offered significant social boosting that kratom lacked Id be interested in maybe giving it a shot on a sporadic in and out type of deal. A cycle as bodybuilders may cycle steroids.
 
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well it doesn't affect your cognition and your pupils won't be constricted and you won't appear to be inebriated on any substance, and can use it more often than kratom
 
Saying dopamine is responsible for hallucinations and racing thoughts is like saying gas is responsible for a car going really fast and spinning out of control. Of course, if you take away the gas - the car won't go really fast and spin out of control.

Neuroleptics don't take away voices and hallucinations, but rather they drastically slow down the human brain resulting in a reduction of everything the brain is doing, hallucinations and delusions included. People still relapse on neuroleptics all the time although they surely do not have excess dopamine.

Hallucinations and delusions could be caused by a number of things, and if it is biological it is more likely to be the wiring in the brain (which we can't observe).

This is why they say they don't know what causes severe mental illness. The dopamine hypothesis is used as a justification for forcing people with serious mental illness to take neuroleptics (which keeps them under control).

The core confusion, the neurological pathways that have been improperly formed to reinforce delusions and hallucinations, is what has to be dealt with. More importantly, the cause of the confusion has to be removed (and if that cause is spiritual, looking for a biological solution will be an endless race).

After going through this, I feel terrible for people who are court-ordered or kids who are forced to take neuroleptics. What is even more concerning is that I have come to the realization that the people profiting off of this are fully aware that the studies in peer reviewed medical journals are rigged. I saw one that showed that less than 5% of children given what I was given even developed a little anxiety. That's when it hit me. They know better. Akathisia is nothing to play with. It is so bad that a lot of people kill themselves. Of course, the suicide is attributed to the illness and not the neuroleptic.

Hey buddy let me know if/when you get a liver test done what it looks like. I will have mine done in a few months . You might want to get your kidneys checked to since tianeptine is mostly cleaned out of the body by the kidneys not the liver . When I get my test done I will be happy to share my results with you to . Remember I was/still am taking over a gram a day of tianeptine. My girlfriend has gained control over my stash ,and I am now being given 200 mg every three hours to lower my tolerance . I snuck last night ,and got caught taking 650mg to catch a nice buzz, but don't have plans on doing it again ;because I truly want my tolerance to be lowered so I can once again catch a buzz on 200mg ,and not really a buzz that intoxicates me ,but more a a real feel good . The reason I don't want to get my liver ,and such tested is ;because what if something is wrong with my liver? I would have to tell them about tianeptine ,and then this may get it put in the spot light. Something I don't want but it may also save lives if it is truly bad for us because a lot of people are taking it .

I will also be getting some of the Prolintane you told me about to at the first of the month . BTW I am glad the tianeptine mega thread is gone. ;)

EDIT: Also I am taking this stuff for similar reasons you are . All my life of growing up my parents couldn't or didn't want to deal with me so they had me at a doctors getting doped on seroquel ,celexa and many many more ;before stopping on seroquel and celexa that I took for 8+ years . I have been told now by my doctors that the dose i was given of seroquel everyday was a godly amount 300mg aday . I think this is why I feel so sluggish/tired/bored/and hugh brain fog ever since quitting those other drugs that I think are the devil in them selves . This is why I ever started heroin ,and all other opiates ;because it made me feel what I thought/think normal should feel like. It fixed a life long problem I had form taking all the psychotic medicines I have been on while young. All I want to really do is look at my real mom ,and ram all this shit down here throat . She doped me so she didn't have to deal with me ,and the sad thing is this is the case with a lot of kids in the USA today, but because of this its why I started opiates . It seems they feel a empty spot in my brain. Thats the best way to describe it .

To me ever since getting off all this crap my mom had me on I have never been social at all in fact I would hide from everyone. People wanted to tell me its because I am shy, but I think not . All this crap messed my brain up. I get tired of getting out ,and seeing everyone having a normal life playing running around sports people talking everyone having fun ,and getting along ,and me at the same time thinking why can this not me me. Opiates fixed this for me I talk a lot I am social . I play ,and move about much more like a normal person. My dad and fiancée say its only because I am high is why I am like this ,but once again I think not . I live on disability AKA SSI IF YOUR IN THE USA So I could in fact just stay hidden in my apartment ,and never come out ,and be social have friends , but I don't because I want to be a normal social human .


I think god put the poppy on earth for a reason . :)
 
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What happened to the tianeptine megathread?

I can't find it anywhere - I was away on business and when I came back today I was unable to locate it. I'm assuming it may have got deleted because there was a couple posts describing some insane usage (IV, gram+ doses, comparisons to heroin, etc).

I just wanted to add that I had a chance to get a physical addiction built up over the course of two weeks (tolerance builds FAST) and I can say that this is subjectively much worse than Kratom to come off. I'm getting back on Kratom to ease off this stuff. It also gave me methadone-style constipation and in higher doses (500mg) would cause opioid vomiting - the kind that feels good to hurl, if you have puked on opioids you know the feel.

Anyways I hope this warns some of you that may think it's relatively benign - it's not, and it's actually a very poor choice for weaning off classic opioids due to the extremely short half life and relatively high dosage requirements. It did however kill my cravings for the classic opioids, so there's that.

I feel bad for the nootropic community that are essentially thinking this is some racetam-esque drug, when they're in fact likely micro-dosing a mu-agonist.
 
i think they are aware that its a novel anxiolytic antidepressant

its not that difficult to research
 
I realize that, perhaps using racetams was a poor metaphor, but what I'm trying to say is many of them are downplaying the opioid agonist mechanism as I've actually seen a couple vendors who post on reddit say that there aren't any appreciable effects at MOR - which is just flat out wrong. I know of no other drug that can completely remove classic opioid withdrawal symptoms and trigger classic opioid withdrawal upon cessation without having an appreciable binding affinity at MOR and/or DOR.

EDIT: See this vendor's post:

NSFW:
tianeptine.jpg


That vendor is a bit off base. The Ki and EC50 determine the concentration that a drug will be active at, not how efficacious it is. Just because tianeptine has lower affinity then morphine doesn't mean that it couldn't produce just as strong an effect, as long as it is present in the brain at a high enough concentration to occupy mu receptors.
 
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Apparently somebody deleted it. Here's the link to the thread: http://www.bluelight.org/vb/threads/747835-Tianeptine-Megathread-v1

Something tells me the OP deleted as he said in one of his first few posts that he was unsure whether or not he wants to bring light to the substance. Afaik it's against the rules to delete a megathread so if this is the case we may see it again. If for whatever reason a mod deleted I'd like to know why.
 
You need to forgive your mom. It was terrible having you on a neuroleptic, akin to abuse, but she didn't know what she was doing. The doc told her to do it. Maybe it was because she didn't want to deal with you, but everyone in this life is under the same duress as you in one way or another. Forgive and you will be forgiven. Show mercy and you will be shown mercy. If you forgive others, your Father in Heaven will also forgive you. He will deal with everything. Do not resist an evil person. If your mom does not believe in Christ, it is important to light the Way for her. He didn't come to judge the world, but to save it. Follow His example. Only speak of His mercy. Do not speak of His judgments. The eternal fire is real and we don't snatch people from it by threatening them with it. It doesn't work. They have to hear about His mercy.

I'm happy that you are working on your relationship with God. He listens and He forgives. Don't ever doubt that He forgives. He has bared you, He will bare you, and indeed He will deliver you. Run the race to the end according to the rules and you will be rewarded on the day of Redemption. If none of your work survives the fire, you will STILL be saved, although as through fire. Snatch people from the fire. Show mercy. Put away all wrath and anger. Do not grieve the Holy Spirit who has sealed you in Christ for the Day of Redemption.
 
Can I.V. tianeptine really cause limb loss or was that like a joke or something? I can get it and my favorite ROA is I.V., I have to shoot my opioids. What's a normal dose of this drug for someone with no tolerance to opioids?

No he was not joking. Over in Russia there are people that desperately try to get a opiate high that they IV Tianeptine and its horrible for your veins and such. DO NOT IV Tianeptine, just take it orally! So if your plan is to IV Tianeptine then just don't even go looking for it, its too dangerous and that ain't no BS.. Just look at the Russians that have done it and the limbs and nasty necrosis which comes along with IVing Tianetpine.
 
Does it offer any benefits over kratom for depression? because I take kratom 1 day on 2 days off but it isnt really good for fixing my social mysanthropy which is the root of my problems. So im still looking at what I can use to give me more social oomph. (Please no worthless advice on excecise and good diet etc heard it 1 billion and one times. I do that already and am still a miserable worthless cretin seething with hatred)

People are mostly saying now that all its effects are due to the opiate activity and so its just like microdosing any opiate. If that is the case then Id be wasting my time taking it vs kratom wouldnt i? Also Im more comfoprtable taking kratom since it has a longer history of use.

Or is there more to the effects than that?

Also people talking about it being recreational at high doses. Is it any more fiendish than kratom or less so? Someone posted relative affinities on opiate receptors of kratom vs tianeptine recently but I didnt understand it. If it is less powerful an opiate than kratom then I shouldnt have problems should I since I have no problems at all with kratom usage?

As I said kratom hleps somewhat but not the whole package but there is no point continuing looking down the route of tianeptine if it won't offer any significant benefit over kratom.

Tianeptine is a very mild μ opioid agonist (Ki Human of 383±183 nM, and EC50 Human of 194±70 nM,  and EC50 Mouse of 641±120 nM for G-protein activation). It is very well tolerated, and has a lot more to its mechanisms than the minor opioid affinities.

Here are some pKi values for real μ opioid agonists:

7-hydroxymitragynine (Kratom)- 8.01 nM
Morphine- 4.55 nM
Methadone- 3.16 nM
Naltrexone- 0.39 nM
Oxycodone- 23.4 nM

Above is the quote from the guy talking about affinities. No idea if they are accurate or not but if someone could explain and attest to their validity or lack thereof. Presumably lower number means more powerful?

I suppose one also must take into account the relative bulk of the two substances. Ie you could easily eat a load more tianeptine than you could kratom but the question remains whether the inclinition would be there. From what I read even the recreational users who have a history of opiate abuse can stop using tianeptine pretty easily when they decide enough is enough.
 
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