beyond-infinity
Bluelighter
I origionally started a thread similar to this on the ecstasy forum but most comments were anecdotal rather than theory based.
I'm curious as to the scientific reason i.e. with regard to brain chemistry, how it is that some people do not suffer from comedowns, or even feel in any way different to normal after having done large amounts of drugs (specifically ones that deplete brain chemicals). My girlfriend regularly takes high doses of MDMA. Anything up to around 12 strong pills in a night. She get's the full effects, strong euphoria, great buzz, but says she feels completely normal from the day after. She does get moody and irritated often within the 24 hour period after the session, but after that she's fine. I'm with her regularly and I don't see any changes in her either, anytime after then.
I recentley got chatting to a girl who said she has never experienced a comedown on anything and had been taking pills (e,speed) every weekend for the last 16 years.
Doing that many ecstasy pills must completely deplete you of serotonin. Surely without serotonin or severely lacking in it would cause you to feel different in some ways or other. I get strong comedowns i.e. depression, poor concentration, moodyness etc. after just a couple of good pills and I think it is very common to get some kind of a comedown, even if just poor concentration and laziness.
So is it just that a small percentage of people somehow have brains that are able to replenish their serotonin 10x faster than the rest of us (even without the aid of food - in my gf's case she sometimes doesn't eat for a day or two after), or are there any other credible theories as to why this happens?
I'm curious as to the scientific reason i.e. with regard to brain chemistry, how it is that some people do not suffer from comedowns, or even feel in any way different to normal after having done large amounts of drugs (specifically ones that deplete brain chemicals). My girlfriend regularly takes high doses of MDMA. Anything up to around 12 strong pills in a night. She get's the full effects, strong euphoria, great buzz, but says she feels completely normal from the day after. She does get moody and irritated often within the 24 hour period after the session, but after that she's fine. I'm with her regularly and I don't see any changes in her either, anytime after then.
I recentley got chatting to a girl who said she has never experienced a comedown on anything and had been taking pills (e,speed) every weekend for the last 16 years.
Doing that many ecstasy pills must completely deplete you of serotonin. Surely without serotonin or severely lacking in it would cause you to feel different in some ways or other. I get strong comedowns i.e. depression, poor concentration, moodyness etc. after just a couple of good pills and I think it is very common to get some kind of a comedown, even if just poor concentration and laziness.
So is it just that a small percentage of people somehow have brains that are able to replenish their serotonin 10x faster than the rest of us (even without the aid of food - in my gf's case she sometimes doesn't eat for a day or two after), or are there any other credible theories as to why this happens?