• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe | Cheshire_Kat

Phenethylamines The Small & Handy 2C-EF Thread

Sure no problem! But it is going to take a couple of weeks, because I still want to do the 2c-ef at a higher dose so I can understand the effects better.

Also, I'm not particularly good at describing psychedelic experiences, but I will do my best! 😊

It may also be cool to compare it 2c-p, as it is so closely related to 2c-e.
But that is going to take at least another week, but probably more because such a long experience takes up a whole day out of my schedule, even though 2cp doesn't affect me too long.
 
I have a feeling that 2C-EF is also going to be quite similar to the halogenated 2C-x because of its similar electronic effects and polarity. The Br and I electrons appear to interact with the Phe234 residue through some π-interaction in the 5HT2A binding site and I guess the F on the 2-ethyl does the same thing. Nevertheless I'm really excited about a full dose of this one!
 
Last edited:
perpetualdawn said:
I was thinking about 2C-DF/2C-MF aka 4-(2-Fluoromethyl)-2,5-dimethoxyphenethylamine
Apparently 2C-F is very non-potent but maybe 2C-DF would be worthwhile. I couldn't find any info on it compound, I wonder if it's been tried.
Click to expand...
Fluorine attached to a carbon atom next to a benzene ring (in the so-called benzylic position) is not inert, and PEAs with a 4-(fluoromethyl) group are likely to be unstable (at best) or to behave as alkylating agents in the organism (at worst).

Difluoromethyl group is more stable (2C-DFM reacts with 2,4-dinitrophenylhydrazine / dil. H2SO4 only on mild heating). However, metabolic 5-O-demethylation can lead to alkylating agents again.
(Examples of reactivity of difluoromethyl groups can be found here:
Y. Pan. The Dark Side of Fluorine. ACS Med. Chem. Lett., 2019, 10 (7), 1016–1019, DOI: 10.1021/acsmedchemlett.9b00235
Bioorg. Med. Chem., 2012, 20, 2739, DOI: 10.1016/j.bmc.2012.02.001
Bioorg. Med. Chem., 2006, 14(24), 8386, DOI: 10.1016/j.bmc.2006.09.002.)

2C-DFM hydrochloride was tested a couple of times by me and my wife. Threshold dose is 6.5 mg p/o; a +2 experience required 15 mg p/o. Apparently, it is slightly less potent than 2C-B.

Trifluoromethyl group (like in 2C-TFM) is the most stable of the three. Nevertheless, 4- or 2-(trifluoromethyl)phenols are not perfectly stable in a solution, and so there is the same concern of 5-O-demethylation of 2C-TFM.

W. B. Whalley
Organic fluoro-compounds. Part I. Hydroxy-derivatives of benzotrifluoride
J. Chem. Soc., 1949, 3016.
DOI: 10.1039/JR9490003016

Andrew E. Feiring , William A. Sheppard
Fluorinated hydroquinones
J. Org. Chem., 1975, 40(17), 2543.
DOI: 10.1021/jo00905a032

David A. Ellis and Scott A. Mabury
The Aqueous Photolysis of TFM and Related Trifluoromethylphenols. An Alternate Source of Trifluoroacetic Acid in the Environment
Environ. Sci. Technol., 2000, 34(4),632.
DOI: 10.1021/es990422c
 
Last edited:
realgar said:
2C-DFM hydrochloride was tested a couple of times by me and my wife. Threshold dose is 6.5 mg p/o; a +2 experience required 15 mg p/o. Apparently, it is slightly less potent than 2C-B.
Click to expand...
How'd you like it? Duration and effects? Not to derail from the topic 2C-EF, but I am kinda curious ngl.

Also, thanks for the other information. Very interesting and good to know.
 
realgar said:
2C-DFM hydrochloride was tested a couple of times by me and my wife. Threshold dose is 6.5 mg p/o; a +2 experience required 15 mg p/o. Apparently, it is slightly less potent than 2C-B.
Click to expand...
Psychestim said:
How'd you like it? Duration and effects? Not to derail from the topic 2C-EF, but I am kinda curious ngl.
Click to expand...
2C-DFM hydrochloride, 3 mg in aqueous solution orally - nothing.

--------

2C-DFM hydrochloride, 6.5 mg orally - threshold effects, similar to 2C-B and probably more enjoyable.

--------

2C-DFM hydrochloride was tested by a woman <...> years old, and weighing about 60 kg.

T+ 0:00. 15 mg orally, with water.
T+ 1:40. A little over half an hour ago I felt slight physical changes. Until then I was very lazy, sleepy and cold.
T+ 1:43. I took another 5 mg orally with water. On a cognitive level, the effects are weak, but the visuals are serious: morphing, breathing. Time passes very slowly.
T+ 2:18. The intensity of the visuals from the first portion has noticeably decreased, and the supplement is not felt yet.
T+ 2:25. The supplement began to come on: the intensity of the visuals increased.
T+ 2:30. It's getting cold again.
T+ 2:52. I am chatting online. Everything is normal. I am hungry (the last time I ate was 6 hours ago).
T+ 3:22. Had a meal. Drinking coffee and looking at wallpaper – interesting.
T+ 5:02. Fell asleep.
T+ 11:38. Woke up with a severe headache, took ibuprofen and went to bed.

Summary.

The substance starts to act in 40-50 minutes. At first, altered bodily sensations appear (not pleasant, but not negative either), it becomes cold, and strong drowsiness appears. After that, quite intense OEVs appear, mainly morphing and breathing.

There were no visuals with closed eyes, color distortions, flickering, glitter, fractals, geometry or complex structures. Visual perception was better with glasses than without them (I think this is an important detail, since with some substances visual perception does not change at all depending on the presence of glasses).

There were almost no cognitive changes, as well as original thoughts, enlightenment, etc. During the entire period of action, sobriety and ordinariness of mind were maintained.

The pupils were slightly dilated, but there was no noticeable stimulation of the central nervous system. On the contrary, I wanted to lie/sit still.

I did not notice any aftereffects on waking up.
Click to expand...
 
Last edited:
I tripped on 20mg 2C-EF (confirmed real) the other day and took another 10mg just now, man it was so warm, euphoric, visuals on par with LSD, was like the laughter and light fun of 2cb mixed with heavier visuals on a much lower dose than I thought, 16 hours after ingestion I still had text moving on my screen so it has either a logn halflife or a long duration and long offset.

Come up is deff like 2 hours though, maybe 1hour 30 for some, it was only by 4-6h that the peak started, which lasted some time. I did fall asleep whilst still heavily tripping due to taking benzos as it was 6 am at that point, woke up at 11 am and was still tripping visually (very minor visuals) until about 3-4pm, took 15mg at 10 pm and redosed 5mg at 23:55..

Why does this amazing substance come out so close before the ban? :(:(:(
 
Carterwest36 said:
I tripped on 20mg 2C-EF (confirmed real) the other day and took another 10mg just now, man it was so warm, euphoric, visuals on par with LSD, was like the laughter and light fun of 2cb mixed with heavier visuals on a much lower dose than I thought, 16 hours after ingestion I still had text moving on my screen so it has either a logn halflife or a long duration and long offset.

Come up is deff like 2 hours though, maybe 1hour 30 for some, it was only by 4-6h that the peak started, which lasted some time. I did fall asleep whilst still heavily tripping due to taking benzos as it was 6 am at that point, woke up at 11 am and was still tripping visually (very minor visuals) until about 3-4pm, took 15mg at 10 pm and redosed 5mg at 23:55..

Why does this amazing substance come out so close before the ban? :(:(:(
Click to expand...
It definitely made me chuckle! What an intoxicating, wobbly blast that molecule is. Not sure i could manage more that 12mg thou, pretty potent stuff! I think it's really about the cathinones isn't it, the amount that gets consumed is probably leaving the fishes in the river spangled! :tweaker:
 
Fascinating thread. I had not heard of a difluoromethyl 2C, much less an actual report. So thank you very much @realgar i doubt this information is very available, and while I'm sure the world's experience lies mainly with you and your girlfriend, I'm tempted to make a dedicated thread just so the world has an easily available reference.

The trifluoromethyl has been on the top of my list for some years now. The TFE, less so, but I am curious.

So what is the overall consensus?
Is 2C-EF more like the 4-alkyl or 4-halo 2C-x's?
 
What a phenomenal psychedelic! Definitely grab some if you can, if you’re a fan of PEA’s you don’t want to miss out on this one. I took 10mg yesterday morning because I felt a bit rattled the last couple of days and man did I have a cathartic cry. It was a beautiful and emotional experience that took me back a few months to think about stuff that I thought were dealt with but apparantly there was still some unresolved stuff I had to go through. As it was so emotional and introspective I wasn’t really able to focus on the visual aspects but there were definitely some cool CEV’s and a bit of drifting/shifting, granted a bit mild at 10mg. The bodyload was pretty light IMO but I’m used to heavy bodyloads as a fellow PEA lover.

Overall, I think a full dose for me would probably be around 15mg. It’s warm, euphoric, clear-headed and emotional like 2C-B but deep, introspective, and visually more similar to 2C-E. Can’t wait to take this one again!

Edit: Oh and no headache on the comedown and in the morning! Very unusual for me after a day on a psychedelic PEA/AMP. Maybe 20mg telmisartan helped that I took before the trip or the 2C-EF really makes me less prone to getting one. Time will tell.
 
Last edited:
Hey,

How is 2C-EF compared to regular 2C-E? Is the bodyload better? How long does it last? I'm bit off the loop with the newest RC. I haven't followed the new trend since 2015 (ALD-52 and 1P-LSD were the latest psychedelics I've known about).

Thank you
 
HofmannBlotter said:
How is 2C-EF compared to regular 2C-E? Is the bodyload better? How long does it last? I'm bit off the loop with the newest RC. I haven't followed the new trend since 2015 (ALD-52 and 1P-LSD were the latest psychedelics I've known about).
Click to expand...
Not too confident in comparing them yet because of my limited experience but per mg 2C-E seems more intense to me. 2C-E is mind-warping, has insane auditory visuals and is just a weird but deeply satisfying psychedelic. 2C-EF seems gentler but can be just as introspective as 2C-E. No idea how the bodyload will change but at 10mg it was quite light and never bothersome. Main effects lasted 8 hours with a few hours of residual effects. Took 0.25mg Halcion 10 hours after intake and also vaporized a bunch of THC so not too confident on duration either.
 
Psychestim said:
Not too confident in comparing them yet because of my limited experience but per mg 2C-E seems more intense to me. 2C-E is mind-warping, has insane auditory visuals and is just a weird but deeply satisfying psychedelic. 2C-EF seems gentler but can be just as introspective as 2C-E. No idea how the bodyload will change but at 10mg it was quite light and never bothersome. Main effects lasted 8 hours with a few hours of residual effects. Took 0.25mg Halcion 10 hours after intake and also vaporized a bunch of THC so not too confident on duration either.
Click to expand...
How many trips do you have with the 2C-E? Just the two experiences, with the 12 mg beauty and the beast one? In my experience 10 mg of 2C-E were still relatively light for me, but 13 - 16 mg experiences really caught me off-guard. I wonder how much your 12 mg experience was idiosyncratic or representative of your sensitivity to the material. You should certainly repeat the experience, the world needs more people taking 2C-E, crying both in agony and beauty, often at the same time! Your ~ 3 mg report made me believe 2C-EF could be more potent than 2C-E (of which 10 mg are still quite light for me)... Then again, in the upper range, intensity is highly influenced by the nature of the compound.

I've seen a number of reports now that compared 2C-EF to LSD regarding its depth, which of the phenethylamines is typically reserved for 2C-E or perhaps some of the DOx.

In any case, the more I read about 2C-EF, the more of a winner it seems. I may have to retract my (private) statement of only being mildly interested in it due to the 'plain' bioisosterism to 2C-B and 2C-I. It does seem unique (then again, every compound is...).
 
xdrc said:
How many trips do you have with the 2C-E?
Click to expand...
Either three or four experiences, not too sure. The 12mg trial was the first experience with 2C-E powder though. The pellets I bought many years ago were pretty unreliable and had a huge spread in dosage. One was tested at 8.9mg and another one at 13.4mg. I think I ate them both at separate times and another one that wasn‘t quantified so I‘m pretty unsure about the exact doses I took. I‘m willing to bet that my 12mg reaction was idiosyncratic and I want to retry soon. Also want to try a higher dose of 2C-TFM soon and see how those compare. They felt similar too IMO but TFM had more OEV‘s and was physically more transparent, at 3mg at least.

xdrc said:
3 mg report made me believe 2C-EF could be more potent than 2C-E (of which 10 mg are still quite light for me)... Then again, in the upper range, intensity is highly influenced by the nature of the compound.
Click to expand...
I would‘ve expected it to be stronger at 10mg too tbh but it was very liberating and emotional nevertheless so absolutely not a waste of time.
Idk 10mg felt similar to 20mg 2C-B HCl in intensity maybe, or perhaps equipotent to 2C-E HCl.

xdrc said:
I've seen a number of reports now that compared 2C-EF to LSD regarding its depth, which of the phenethylamines is typically reserved for 2C-E or perhaps some of the DOx.
Click to expand...
I would agree. Similar in terms of depth but more structured and clear-headed. Considering I was alone the whole time I was able to get myself out of thought loops pretty easily and was able to think rationally about my situation after a while. No idea how that will change at higher doses though.

xdrc said:
In any case, the more I read about 2C-EF, the more of a winner it seems. I may have to retract my (private) statement of only being mildly interested in it due to the 'plain' bioisosterism to 2C-B and 2C-I. It does seem unique (then again, every compound is...).
Click to expand...
Yeah it does seem to possess qualities of both 2C-E and the halogenated 2C compounds.
 
Last edited:
Psychestim said:
Not too confident in comparing them yet because of my limited experience but per mg 2C-E seems more intense to me. 2C-E is mind-warping, has insane auditory visuals and is just a weird but deeply satisfying psychedelic. 2C-EF seems gentler but can be just as introspective as 2C-E. No idea how the bodyload will change but at 10mg it was quite light and never bothersome. Main effects lasted 8 hours with a few hours of residual effects. Took 0.25mg Halcion 10 hours after intake and also vaporized a bunch of THC so not too confident on duration either.
Click to expand...
I've had 15mg years ago and it was still easy to handle. One thing that amazed me was at 15mg I had an urge to dance (more than MDMA even). The bit I remember is that the person who took the other 15mg (B9) commented "he moves in mysterious ways" after I danced my way through 'Achtung Baby'!
The friend who sent me 30mg to try (about 15 years ago) said he was a tad worried that everything else with a 2-fluoroethyl group in it killed all the test animals they used in research (due to 2-fluoroethyl groups that came away from the test compound, inhibited the citric acid cycle by substituting for acetic acid with much greater affinity and once substituted, could not go any further). I assured him that no biochemical reaction could remove the 2-fluoroethyl from the benzene ring. He was more than pleased, after sending him a letter claiming it was the best drug to dance with!
 
Last edited:
You must log in or register to reply here.
Top