The positives and negatives, ups & downs of using tramadol

[cmpetr2k]

It seems like when I use Tramadol recreationally it works like an anti-depressant several days after use. I suffer from clinical depression. Has anyone heard about or experienced this? Or is it all in my head?

 

[bunge]

Yeah its a well known effect, tramadol has an ssri effect alongside mainly kappa opioid effects.
This extra srni effect is believed to aid in a small way its painkilling properties, as well as causing a noticeable mood-lift.

 

[cmpetr2k]

I never knew that till just recently. I suffer from major clinical depression. The trams work better as an anti-depressant then any thing else I've ever tried, and I've tried A LOT of different meds throughout my life. I wonder if there is a dose of tram that's safe and effective for long term use. I tried to find this subject online but with limited success

 

[bunge]

Their are snri anti-depressants, venlafaxine is an snri I believe, as is Duloxetine.
I don't think tramadol is advised for longterm (or short-term) anti-depressant use.
However, most doctors seem to be happy enough prescribing it for long term pain relief, so I would say that if you can keep it within prescribing limits ie.100mg every 6-8hrs and no-more then 400mg a day, then it shouldn't be any more dangerous then using them for pain relief.
if you notice any bad changes to your depression symptoms though then I would see your doctor at the first opportunity.

 

[cmpetr2k]

Their are snri anti-depressants, venlafaxine is an snri I believe, as is Duloxetine.
I don't think tramadol is advised for longterm (or short-term) anti-depressant use.
However, most doctors seem to be happy enough prescribing it for long term pain relief, so I would say that if you can keep it within prescribing limits ie.100mg every 6-8hrs and no-more then 400mg a day, then it shouldn't be any more dangerous then using them for pain relief.
if you notice any bad changes to your depression symptoms though then I would see your doctor at the first opportunity.

I see. Thanks for the info. Then next step for me is to discuss it with my psychiatrist. I've been suffering for a long time and been a guinnie pig for so many meds, its hard not to get my hopes up, even though I probably shouldn't. I'm so tired of this. If something doesn't work for me soon, I just don't think I can hold out much longer. I just made an appointment as soon as possible (in two weeks) to see her.

 

[Intenselife]

Someone in one of my threads wrote this too, that in Russia and some other countries they prescribe tramadol for depression. I personally would think that most doctors/psychiatrists here would not prescribe them to someone for depression but you never know. Although they are one of the weakest opiates, i have heard they do cause terrible withdrawals just for an fyi.

 

[cmpetr2k]

Ok thanks intenselife.

 

[Intenselife]

Lol you live in missouri too, kansas city?

 

[bunge]

I can attest that the WD from tramadol is mean as hell.
I used codeine to help with the WD but i didnt know about the snri WD and it hit me hard, with loads of anxiety and about 4/5 panic attacks a day.
I think sleep would have been difficult too but i had some diazepam (and zero tolerance) annd 2-4mg helped lower my anxiery enough to sleep.

 

[cmpetr2k]

I sure hope I find a doctor who will work with me on this, because after 20 years of trying this and that to no avail I'm going to use this cause I know it works even if I have to get it on the streets from now on.

 

[snowblowjoe80]

am I the only person in the world that dwiththe 't feel shit from tramadol? I know my products Were legit and I took huge doses and barely felt anything whatsoeve, tramadol sucks ass. Itslike taking weak tylenol with codeine

 

[Venrak]

Your metabolism doesn't allow you to get much from it.

Get mad with your liver, I guess?

 

[bunge]

As venrak said its a liver thing. You dont have alot the enzyme responsible for converting tramadol into o-desmethyltramadol, which is responsible for all the opiate loveliness.