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The Old and Overgrown Methylone Thread (11-2002 to 2-2007)

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I agree with Fizzacyst. Redosing methylone will bring a part of the euphoria back, if you dose almost as high as the original dose, but it will fade even faster and just extend the unpleasant comedown. However, if I'm using it to feel good (as I mentioned in my last post, as opposed to using it to enhance social interaction), it always makes me fiend for more. I've redosed 3 times in one night before, going through over 600mg. Luckily, no matter how much I've used, it never seems to affect me past the actual comedown, unlike MDMA. I always feel just fine the next day, whereas with MDMA, especially if I redose, I'm just a mess for half a week.
 
Yet another vote...redosing for me never extended the duration...just lead to too much stimulation and a rough come-down (which I normally never get with methylone.) The nature of the experience is short, just as a DMT experience is short. This is why this drug is anything but recreational.
 
They have found the Methoximethcathinons to be metabolites of Methylone (go read also about the Methedron analog):

Rhe urinary metabolites of methylone in humans and rats were investigated by analysing urine specimens from its abuser and after administrating to rats with gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-electrospray ionization mass spectrometry (LC-ESI MS), using authentic standards. The time-course excretion profiles of methylone and its three metabolites in rats were further investigated after a single intraperitoneal dosing of 5 mg kg-1 methylone hydrochloride. Two major metabolic pathways were revealed for both humans and rats as follows: (1) side-chain degradation by N-demethylation to the corresponding primary amine methylenedioxycathinone (MDC), partly conjugated; and (2) demethylenation followed by O-methylation of either a 3- or 4-OH group on the benzene ring to produce 4-hydroxy-3-methoxymethcathinone (HMMC) or 3-hydroxy-4-methoxymethcathinone (3-OH-4-MeO-MC), respectively, mostly conjugated. Of these metabolites, HMMC was the most abundant in humans and rats. The cumulative amount of urinary HMMC excreted within the first 48 h in rats was approximately 26% of the dose, and the amount of the parent methylone was not more than 3%. These results demonstrate that the analysis of HMMC will be indispensable for proof of the use of methylone in forensic urinalysis. PMID: 16891251 [PubMed - in process

http://www.mdma.net/methylone/metabolism.html
 
And then there's beta-MeO-MDxA, which has 4 possible stereoisomers.
And beta-CO2(CH3/CH2CH3)-MDxA, which also has 4 possible stereoisomers.
 
i took 200mg for the first time about a week ago and it made me very depressed. i had an alright body buzz but just felt real sad and had no motivation to talk or do anything really, like coming down off of amphetamines. i'm never doing it again. it also turned into what looks like piss and smells like rotten fruit in water. well has anyone else had some major depression after taking it, lasting about 2 or 3 hours?
 
Yes, if you don't channel your energy, about an hour after the initial rush hits it drops off abruptly and becomes dysphoric for some people. I suggested some ways to deal with it above. It probably turned nasty in water because it grew bacteria or something similar. Try putting your chemicals in a mixture of distilled (important) water and alcohol. Vodka works, as does distilled water and Everclear. The alcohol will stop contaminants from forming. Also, keep it cold.

Apart from that, it just doesn't agree with some people. I had a few reactions like your though, and eventually I found out how to work with it, and now I enjoy it although I rarely use it.
 
ya the depression come on quick for me, within 20minutes. yes distilled is a good idea. do you think 2 or 3 shots in about a half litre of water would be adequate for killing bacteria? i mean, i know using pure 80 proof would work well but i dont want to evaporate alcohol every time i want to use or redose if i desire, and i definately dont want to get drunk!
 
Coolio, I don't smoke herb anymore, and I wasn't craving it after the rush was over. Is it possible this stuff is varying batch to batch? Also like I stated before people are different.
 
Just dissolve a gram in 100mL of vodka. Then you have 10mg/mL. Or you could get distilled water and Everclear and combine 80mL of water and 20mL of Everclear to make a weak 20% alcohol solution. Dissolve the gram in that, and you definitely wouldn't get drunk when dosing.

Don't just start dumping shots into large volumes of water. Unless you're exact, you won't know how much you're taking.
 
methylone is pretty much the only chem I do right now, I usually take 220mg then 180-190 2 hours later and can come back up, I have no problems with redosing. I do sip goldschlager throughout which extends the experience somewhat.
 
/\ WHAT'S that? Is that beer?

I like to drink beer on my methylone trips. And I find that it can indeed be extended at least once. Say, 150-170mg followed by 100-170mg... and I have successfully used it as a recreational substance both for going out and for making music. . . it is short-lived, and sometimes (set/setting-related... mainly set I feel) it can be over very abruptly, with only the stimulation left, and the sad, sensitive thoughts that go with that. But as Xorkoth said, it depends on what you make of it, and this is not necessarily an inherent part of the experience.
 
I like to snort methylone.

Goldschlager is somewhat viscous, high alcohol content, cinnamon flavored liquor with flakes of gold suspended in it.
 
Goldschläger is a Cinnamon based liquor with Goldflakes in it (yeah I'm a Goldbug).Can't believe to read about here!It used to be popular way ago,but I guess it is about to come in vogue again-check your barkeeper if he can make you some.If he's worth his money he won't sweat bullets on the word Goldschläger =D
 
Jagermeister is flavored with para-methoxy-1-isopropenylbenzene and, in Germany, used to contain codeine as well.:D
 
Time to revive the old Methylone thread with 4 new questions :). I have not tried Methylone yet, but am still curious:

1. Has anyone tried taking Ketamine as the Methylone starts to subside? I do that all the time with MDMA, and if it doesn't prolong the peak, at the very least it makes the comedown less harsh for MDMA.

2. Has anyone tried taking an SSRI/SNRI at return to baseline?

3. Has anyone taken Methylone while on Selegiline?

4. Does anyone else other than GP (thanks as usual GP :)) have input on Methylone + Opiates?

Helios. said:
para-methoxy-1-isopropenylbenzene
Click to expand...

Yep, and you can also find this strangely PMAish-sounding substance in your favourite Anisette, too. As a matter of fact, it is none other than Anethole, the essense of anise. And before anyone gets excited, no, it does not turn into PMA in the liver; nor does the same go for Safrole into MDA, or Asarone into TMA2 ;).[/end of completely irrelevent anti-spice-to-amp-in-liver-soapbox]
 
Not exactly sure if this is what you meant, but:

4) I've sucessfully used smallish doses (maybe 15-30mg) oxycodone to ease the comedown from methylone on a few occasions. The oxycodone woke me right up, but did not seem to cause excessive stimulation. I was able to fully enjoy the oxy for a couple hours and then go to sleep.
 
I've never had MDMA before, would Methylone be a good alternative to this? I have a supplier that has really good deals on this. I can get five grams for the price of 2 from a different vendor. I've very intrested in Methylone. I've read a lot about it. I don't think I've ever experience this "euphoria" everyone talks about.
 
Its not an MDMA substitute. Since you've never had MDMA you won't be able to make a comparison between the two, but I think a lot of people try it looking for an MDMA-type high. Its really a totally different drug.

There are similarities, but probably far more differences.
 
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