Limpet_Chicken
Bluelighter
- Joined
- Oct 13, 2005
- Messages
- 6,323
I 'smoke' one of those E-cigs now, and get through very few actual rollups indeed, and the NRT is really effective for dreaming.
Another herb I can recommend for this action, is of all things, valerian root extract (caps of dehydrated powdered extract are the easiest to work with).
Don't bee alarmed if it fucking stinks to high heaven, valerian root and its extracts and tinctures smell kinda like a cross between a blue cheese that has gone actually bona-fide moldy and decayed, sweaty socks covered in toe cheese chunks and stale cat piss, but its produced THE most vivid dreaming I've ever experienced.
There does seem to be a pronounced tachyphylaxis with valerian however (short term, short lived tolerance that rapidly spikes upon taking the drug producing it)
Larger (much larger) doses of the caps/pills are needed though than for sleep induction, I typically use the whole pack, although it should be noted, that whilst not physically dependent (or psychologically either for that matter), I do have some GABAergic tolerance most likely due to my taking chlormethiazole twice a day, but its obviously not too extensive, given that the stuff remains perfectly well effective.
Valerian is interesting, in that some of the active constituents bind to and act as allosteric positive modulators at a novel binding site at the GABAa receptor complex, IIRC its the same as the one that recognizes loreclezole.
Always fancied trying loreclezole myself, to see if it produces the same sorts of effects on dreaming that valerian does.
As long as its properly cured, dried etc. to detoxify it, Amanita muscaria too acts as a GABAergic hypnotic with strong pro-dreaming effects, perhaps the only drug I've tried that is anywhere near so powerfully effective in this respect. Peripheral cholinergic side effects are effectively dealt with using Buscopan (hyoscine/scopolamine butylbromide quaternary salt, a quat like the cholinergic poison in the fly agaric, so both can effectively be limited to outside the CNS; the former to counter the latter, as muscarine is also a quat and won't pass the BBB.
Another herb I can recommend for this action, is of all things, valerian root extract (caps of dehydrated powdered extract are the easiest to work with).
Don't bee alarmed if it fucking stinks to high heaven, valerian root and its extracts and tinctures smell kinda like a cross between a blue cheese that has gone actually bona-fide moldy and decayed, sweaty socks covered in toe cheese chunks and stale cat piss, but its produced THE most vivid dreaming I've ever experienced.
There does seem to be a pronounced tachyphylaxis with valerian however (short term, short lived tolerance that rapidly spikes upon taking the drug producing it)
Larger (much larger) doses of the caps/pills are needed though than for sleep induction, I typically use the whole pack, although it should be noted, that whilst not physically dependent (or psychologically either for that matter), I do have some GABAergic tolerance most likely due to my taking chlormethiazole twice a day, but its obviously not too extensive, given that the stuff remains perfectly well effective.
Valerian is interesting, in that some of the active constituents bind to and act as allosteric positive modulators at a novel binding site at the GABAa receptor complex, IIRC its the same as the one that recognizes loreclezole.
Always fancied trying loreclezole myself, to see if it produces the same sorts of effects on dreaming that valerian does.
As long as its properly cured, dried etc. to detoxify it, Amanita muscaria too acts as a GABAergic hypnotic with strong pro-dreaming effects, perhaps the only drug I've tried that is anywhere near so powerfully effective in this respect. Peripheral cholinergic side effects are effectively dealt with using Buscopan (hyoscine/scopolamine butylbromide quaternary salt, a quat like the cholinergic poison in the fly agaric, so both can effectively be limited to outside the CNS; the former to counter the latter, as muscarine is also a quat and won't pass the BBB.
