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The Cuddle Puddle vers. Mmmmm gum.....

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the methylenedioxy fucks with the binding profiles.
Basically the MD group way way wya way WAY increases affinity for serotonin release, but the affinity for dopamine and norepinephrine release is a lot lower.
thats why MDMA is toxic to sergotonic neurons and methamphetamine/no MD sub is toxic to dopamine neurons.
methylated amphetamines have increased affinity for serotonin release, hence why MDMA supposedly is far more chill than MDA, because moar serotonin less dopamine when the methyl group is thrown onto an amphetamine molecule.
This does not explain why d-methamphetamine has a slightly higher affinity for dopamine release than d-amph though...and also higher affinity for 5HT and less NE release...
dioxy just means 2 oxygens lol...a methylenedioxy group is just 2 methoxy groups i thought, that are bonded together...
 
LSDMDMA&10243567 said:
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This does not explain why d-methamphetamine has a slightly higher affinity for dopamine release than d-amph though...and also higher affinity for 5HT and less NE release...
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The methyl group on amphetamine increases it's ability to pass through brain I figured.
 
Dmeth IS an isomer of methamphetamine.
The levo isomer of methamphetamine is OTC, and unable to cross the BBB effectively/not abusable.
street meth is all d meth hence my comparison.
 
Ondine said:
I learned if you tip the bathroom guy at venues, sometimes they'll give you gum! It's like they know I took ecstasy or something...
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Let's hope he was nice enough to drip a little acid on that piece of gum.
 
Hey all, I'm celebrating my birthday for the next two days by having a camping rave- you won't see me here, no reception! I'll be on fabulous drugs roughly the entire time. The other mods and admin will be around in ED.
 
have fun... :P just found out miracles do exist, after looking for good molly for quite some time the one that hooked me up was a friend of my mom... lol
 
Bsiren said:
Hey all, I'm celebrating my birthday for the next two days by having a camping rave- you won't see me here, no reception! I'll be on fabulous drugs roughly the entire time. The other mods and admin will be around in ED.
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happy birthday!! have fun!!
 
FFFFFFFFFFFFFUUUUUUUUUUUUUUUUUUUUUU

im on like a ++++ trip, and now the bitch that broke my heart wants me to call her


wow against my better judgement I did it. Fucking being bitched at about multiple people I dont even fucking know. Yeah Im not talking with her again.
 
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How bad is it for you if you decide to go drinking again while experiencing a heavy hangover? I'm on the fence.. :( Great party tonight but can't even hold my drink without shaking all over the place lol.
 
Had a really great time on 100mg capsule.

Took about 35 minutes to nearly 45 minutes to kick in (on empty stomach)

absolute locktight smiley face / open teeth smile grin

That was one of my favourite raves ive been to in a longgggggg time :D


did about 400mg of ket throughout the night also (Did the K after the mdma)
 
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