I just tried TMA-2 for the first time, at 30mg.
To me, in a nutshell, it felt kind of like mescaline that never really kicked off. The head space was somewhat similar, but lacked the marked "de-filtering" of experience that always characterized mescaline's effects for me. The visual changes were, as has been discussed elsewhere, not as significant relative to it's head change as I've had with mescaline or the 2Cs. The visuals were like a more subdued mescaline. There was a very small bit of visual movement if I looked for it at the peak of the experience, around two or three hours, and colors and shapes seemed to pop, but I wasn't really impressed by the visual aspect of this drug. There was very little euphoria, and the emotional side of the trip was fairly subdued, but that may have just been the setting I chose for the trip.
The body load was very significant. On the 2C phenylethylamines I've taken, there's a kind of inner tension, vasoconstriction and elevated heart rate that characterises the come-up, but which melts away as the trip really begins around the second hour. This stuff had a similar effect, except it never melted away. My heart rate was elevated for the entire ~9 main body of the trip, and both me and one of my trip partners noticed soreness in our joints as we were coming down. It increased mucous production for a couple of us as well, and I felt like I had a wad of snot in the back of my throat for most of the experience. I experienced mild bruxism, nothing too bad.
If I were to take it again, I might almost like to increase the dose a bit, to maybe 40mg, but I'm hesitant to do so because the body load was so uncomfortable on the dose I took. All things considered, I probably would not take this drug again. It's neat to have been given the chance to try it, if for nothing more than its historical significance in the structure elucidation process of the 5HT2A receptor, but honestly I think I now see now that this drug is really kind of ... obsolete. I would take any 2C drug over this. Life is too short for me to waste it on further TMA-2 trials
