The Big & Dandy Methoxphenidine / MXP / 2-MeO-Diphenidine Thread

[NiceEnough]

It's most likely tolerance, although a bad batch isn't impossible either. You said you've recently done smaller doses of MXP. Did you feel effects from that? MXP seems to have a ridiculously long half life and tolerance so even small doses can build up your tolerance quite substantially. MXE and ketamine probably will contribute to your tolerance as well. With no tolerance I even noticed the effects from 50mg, let alone 200mg.

The closest together I've ever taken MXP was 5 days apart, and even after 5 days I seemed to still have a noticeable tolerance built up (125mg was weaker than 100mg had been 5 days earlier). Based on my limited experience I'd say it will take a minimum of a week to get rid of most tolerance, maybe even up to 2 whole weeks.

MXP really isn't a great dissociative for someone who likes to use them on a regular basis, not only because of the tolerance but also because very little is actually known about its dangers.

Thanks for helpful answer. It seems quite subtle in lots of ways that can be frustrating for someone used to more 'in-your-face' dissociatives like k and MXE. Going to give it a rest, especially as it isn't really working and I do like to use these types of substances regularly so would like to avoid any potential toxicity.

 

[Grottbags]

Another month or so of on and off usage with MXP and I think I have now experienced all and everything it has to offer. From personal experiences over the last 6 months i can confirm that upping the dose of this is useless, pointless and could even be dangerous. It certainly becomes more unpleasant the more you put into your system. Plus after reading some of the posts about the disasters from high doses, I can see how this drug could get out of hand if irresponsibly taken. I recommend the dosage to remain around 80-120mg depending on your own body. People taking this should really have the smarts to know their limits. This is what it all comes down to with legal, illegal and unknown chems afterall. The experience does not get any better by gobbling more and more of this stuff so those who are prone to addictive behaviour/psychologically thinking the more the merrier should probably find another substance or ensure they are capable of control and awareness.

This is the last post I think I will make on this substance as I think everything has been covered that I am capable of talking about. So to conclude:

I think the best way to take MXP is orally. I measure up 100mg in capsules and swallow. I have noticed the chemical seems to somehow stay as a whole blob (I imagine) it goes into my stomach and stays as a whole. Because if I've not eaten, i guess my metabolism processes it quite quickly and it can hit me in around half hour to an hour. When Ive had a big fat dinner and ate a capsule straight after it feels like it must just hang around my stomach waiting to be processed in line. Food goes through first and it can take up to 3-5 hours to kick in. Here's how I discovered and confirmed the motions of MXP based on my body:

Day 1: Had massive sunday dinner about 6:30pm. its been a sunny day. been pigging out on choc and ice creams, smoked a couple of spliffs, im bored. 8:30pm decided to eat a "fun bomb" (100mg capsule MXP, I have 6 left that i made up a week or so ago) Watched tv, didnt feel creative or effects of mxp, in the end as nothing happened, i fell sleep around midnight

Day 2: woke up about 10am, slight fuzzy insides, remembered I'd munched a fun bomb yesterday, so it must have done its thing whilst i was asleep. curious!

Day 3: bored at home again. early afternoon. not eaten a thing so far today. lets eat a fun bomb. BOOM. 1 hour i was bobbling around quite happily, in my last post I said it makes me creative, I use this to start projects (scanning some old flyers, making facebook pages, the whole day learning and absorbing info like a geek. Ended up watching history documentaries on the Tudors Very nice day, filled with knowledge, back to school, felt great.

Day 4 - day off - normal

Day 5: pottering about, not sure what to do with myself, ate some dinner,watched tv, bored. fuck it. lets do a fun bomb and get creative. Ate capsule about half hour after dinner (7pm) Just like day 1, nothing happened. By 9, 10 even 11pm, still no effect. However, id slept alot the day before so wasnt tired so I stayed up watching films and documentaries. Didnt move around much either, just zombied out. Decided to go to bed and read at 1am. Reading about physics and time travel possibilities stirred my brain, i could also start feeling the buzz and by around 2am i noticed the buzz feeling starting up. In the end i spent the next 4-5 hours reading, learning, doing my courses on coursera.org, knowledge, info, brain was like a sponge, absolutely loving this chilled mood lying in bed, mellowed and gaining knowledge of allthings and everything of interest to me. By around 8-9am i felt somewhat tired and turned some comedy on and laid with eyes closed trailing off into dream land giggling in my head at the tv then into dreams and sleep.

Day 6: Did it all again, I have managed to so far apply for 6 volunteering jobs around my local area, im in the processs of looking to move house anyway and have not only sourced a place, ive since then visited and got all that hassle out the way and due to move in 3 weeks, i've read 3 books, and feel very damn productive this last week. Ive not increased my dose. Just one capsule in a day. Ive eaten well and forged a routine. I now understand how long it takes with or without food and I strongly recommend eating first as it detensifys (is that a word?) the buzz leaving you with a nice, lengthly, productive ability to think and process information at whatever task you set yourself.

Very pleased with MXP for getting stuff sorted. Will be keeping a supply in my drawer for future days when much is to be achieved.

If you don't be greedy with it, it is definately a very useful brain tool for studies and absorbing information. One happy Brain Just be careful x

 

[NiceEnough]

Very helpful personal account of experience with MXP above, thank you. Not sure I am quite finished with it yet, but it definitely isn't particular recreational in any real sense. Yesterday took 120mg bombed. Felt relaxed, detached, slightly melancholic at times. Was by the sea so enhanced my appreciation of my surroundings. Came on in about an hour, was definitely gone within 8 with no obvious residual effects. Clearheaded, slight effect on speech though still able to talk. Seems to suit solitary pursuits. Did some yoga on it which was nice. Still not clear about long term value of this stuff. Did feel easy to put my ego out of the way on it which was nice. Also helped me realise I seem to have lost my passport which is seriously annoying but really glad to find out now so I can try and sort something out ASAP. Don't think it would have crossed my mind without MXP. Interesting stuff, well worth careful investigation but don't expect too much. And to echo what has been said above, I really don't think there is much point taking too much (e.g. Much more than 120mg) or redosing. Tolerance builds very very quickly.

 

[phatass]

is there any K like euphoria on this one? or is it more just like at high doses u get that unpleasant WTF is going on DXM dirty feel?

 

[dreamofrc]

is there any K like euphoria on this one? or is it more just like at high doses u get that unpleasant WTF is going on DXM dirty feel?

Nothing approaching the euphoria of K, and at the doses I've tried (up to 150mg) nowhere near any sort of "hole". It feels much cleaner than DXM though, and doesn't cause any sedation or nausea like DXM does. Most of the euphoria from MXP seems to just be enjoying the feeling (or lack of) of your body being completely disconnected and numb. Moving around, walking, dancing, etc feels amazing.

I've found weed has enormous potentiation with MXP as well (even more than with DXM). I usually smoke some around the 2 hour mark (when I start to really feel it) and the weed seems to just kick it into a whole different gear. Much more dissociation both physically and mentally, and more euphoric as well.

 

[dr. dissociative]

Another warning story here I'm afraid - messed up pretty bad the other day. I know I'm probably going to get some shit for being so ridiculously irresponsible with my dosage/actions, but rest assured I have learned my lesson and I am going to be taking a break from dissociatives and probably avoiding methoxphenidine and diphenidine forevermore (tbh the only reason I have been using them at all is because I am currently unable to source MXE - my drug of choice - and as most UK users will probably be well aware of, ketamine is as good as a waste of time and money at the moment). Anyway, I my story is rather long so I will try and keep it as condensed as possible. If anyone is too lazy to read on, the main point I want to make is that this substance is NOT safe at higher dosages (500mg in my case, spread over a day but the majority taken within around an hour). Additionally, this should be common sense to anyone with any knowledge of the drug or dissociatives in general, but it is NOT to be taken in a public setting. Obviously this isn't so much the case with some of the more popular dissociatives such as MXE and ketamine in lower dosages, but after a fair few trials with both methoxphenidine and diphenidine, I have found it near on impossible to properly guage a low recreational dose due to the decievingly long come up.

Anyway, to cut a long story short I consumed an entire half gram bag of methoxphenidine mostly at once except from a couple of smaller dosages earlier in the day. I am well aware that this is an absolutely STUPID dosage, but I have a relatively high tolerance to dissociatives (both natural tolerance and accumulative tolerance from semi-regular binges, although I have never been a daily user of any dissociative for a prolonged period of over a week or two). I had also taken this dosage on a recent occasion at home and had a relatively tame experience, which contributed to my MASSIVE overestimation of my tolerance. I was by myself and the weather was nice, so the plan of action was to walk out to a secluded I had found earlier in my local park and meditate until I felt fit to walk home. However, as I became increasingly dissociated, I found myself wandering out into the city with no particular plan in mind until I eventually had to sit down next to a pavement in a relatively busy part of town. At this point, my memory of the events of the night begin to blur... soon I was in a complete state of either dissociation or delerium (I remember I was joint at the arm with someone siemese twin style, but whether this was a dream state or I was grabbing on to some poor dudes arm as he was trying to help me I have no idea).

Complete blackout for... I have no idea how long but multiple hours. When I started to come to, I finally came to the realisation that I was in A&E. I tried to explain to the doctors there that I was fine to walk home, but was barely able to speak at this point. It wasn't until later that I was told that during the period I had blacked out, I had been taken to the hospital in an ambulance and had apparently was on the brink of death with my blood pressure levels, heart rate, acidity of blood (I don't know much about medicine, but I'm pretty sure acidity of blood was mentioned on multiple occasions).

Essentially my warning ends here, but my story continues lol. Apparently I had been given high dosages of sedatives by the hospital (could have fooled me, was still tripping balls - perhaps past etizolam abuse rendered this medication ineffective). After a couple of hours in A&E under watchful eyes, I was taken to the overnight ward. I requested to leave several times, but was told I was under the hospitals care of duty because of the medication I had been given. At this point I was determined to go home (and since I had left without my wallet, I was under the false impression that I was anonymous at this point - as it turns out I must have revealed my name and address at some point). After several trips to the bathroom to get my bearings, I waited until the police and hospital staff were distracted and walked straight out and back to my flat feeling like a badass... until about 5 minutes later when I recieved a call revealing that I was officially a missing person at this point, and two police officers were on their way to collect me and bring me back to the hospital to have a final blood test.

So I ended up back where I started now feeling a little less badass than before (especially as my parents had been informed that I was now a missing person as they were on my NHS details as my next of kin... luckily I have managed to convince them I was simply ridiculously drunk). I was given final blood pressure and blood tests at this point. This was probably nearing 12 hours after my final dosage, and I was told that I was still in a bad enough way that it was recommended that I stayed the night. Perhaps foolishly, I declined and returned home. I made sure to remain hydrated until I was able to catch a couple of hours kip before getting on with my life. I have noticed no adverse health effects since, apart from sore muscles (although I cannot attribute this to the methoxphenidine as I have been rather active since the experience).

Anyway, that is my story. The message which I want to convey is one of a warning - the increase in blood pressure is very real with this substance (as has been reported elsewhere). Furthermore, don't take high doses of dissociatives in public. At best, you'll make a fool of yourself, at worse, somebody will call an ambulance on you.

Also, no other substances were used on the day of question besides cannabis, which I am well accustomed to.

EDIT: forgot to mention, all dosages were taken orally.

 

[Limpet_Chicken]

Perhaps this was an idiosyncratic reaction?

I myself have taken MXP at doses up to just short of 300mg (IV, at which point, this dosage level has definitely produced some INTENSE holes) and diphenidine at up to 3g spaced over two days, without noting any negatives, aside from the extremely poor solubility of diphenidine in H2O, making 5ml barrels needed if one is going to shoot this without turning into a pincushion.

In contrast to the nasty experience related by dr.dissociative, I've found these to be quite benign and forgiving compounds.

Or perhaps its me thats reacting strangely to them, but thus far I have found absolutely no negative side effects from it, save only once from diphenidine, and that being some mere trifling discomfort upon intranasal administration of a wee pinch or two up the nose whilst on my way home from buying the diphenidine, a low, low dose for me.

Took a nice long scenic walk home after the metro tram system serving my city was down for some sort of repair/renovation work, had to get a replacement bus service, and couldn't for the life of me find the point to get the replacement service home, so had to buy another ticket and get part of the way, then take a shortcut through a nice quiet suburb area.

Gave a nice sparkle to my otherwise stress of a trip home

Been doing diphenidine, and when its available, MXP (awful name, but its being sold as branded 'pellets' labelled 'MXP', containing 145mg per 'pellet' unit. Now in some (UK) head shops [I'll say nothing more precise than 'sold in some shops'] so I guess we are stuck with the name now. MXP and diphenidine both have been flying off the shelves faster than food aid in a gaza slum after a hash oil airstrike, but especially the MXP)

Those who say its shallow, and doesn't seem to produce a hole, at any dose, let me confirm, that it can be anything but shallow, and certainly does not lack the capacity to produce one heck of a hole. IV use seems to me, to be the best way with this one(MXP seems the more suited to this than diphenidine, due to the respectable solubility of MXP compared to that big lipophilic oilslick that is diphenidine)

I've been doing these on the weekends, and every other week come payday, I've recently been going through 3-4g over the weekend (I.V) and had some pretty amazing experiences.

Aside from MK-801 SAR, I think one could extrapolate much from the SAR of the parent compound, lefetamine.

I suspect these may well have some opioid activity, a more likely property in these, than in the arylcyclohexylamines, as was thought to be the case for some of them at one point. Lefetamine itself IS an opioid agonist, on a par with codeine apparently.

I suspect that diphenidine might make a fairly decent detox aid actually, in several respects for opioid users.

One reason of course being the NMDAr antagonism, which is known to reduce/lower development of MOR agonist tolerance, theres some decent stimulant activity, especially in diphenidine IMO, and if there is mild to moderate opioid activity present, then that would help lessen withdrawals also, to something easy to taper off on just the diphenidine/MXP.

Plus diphenidine hangs around, and I mean REALLY hangs around. I've felt the effects of those 3g sessions for a week and a half, week and three quarters almost afterwards, not full dissociation, just great mood lift, afterglow. And I suspect that one or the other of these two may well be more potent opioids than lefetamine itself. I'm a chronic pain patient, not looking to taper, or quit my opioid use, as whilst I do use recreationally, certainly, I still need them to get around without pain.

Currently taking a minimum of 90-120mg IV morphine and 20 of oxy twice to three times a day, yet I was able to almost totally suspend use of the opioids without experiencing withdrawal, and of course, no amount of codeine can stand up to that.

IMO there is much more to MXP and diphenidine than at first meets the eye.
Fucking love 'em so far.

First time I did MXP, I ended up in hell, literally, but not as a suffering soul in purgatory, type experience, but more like an anthropologist, out there to study the hades-native ecosystems.

Fucked up weird, but amazing nevertheless. MXP/diphenidine have both holed me as hard as MXE/4-MeO-PCP/ket ever have, and then some.

 

[phatass]

Thx Dreamofrc

would s/l be a good way to go for a faster come-up (without needles)? better than ssnorting/oral?

edit: parachuted 170mg's, at t +50 minutes i'm very unimpressed, i was expecting something a lot more "in your face", can this drug be "worked" to get desired effects? have i nt given it enough time yet?

edit: ok now i get it

 

[Polytoxic]

In a suicide attempt I ingested 1000mg and was already on a very high dose of Benzos. Tolerance to MXP was low but Benzos high. I was writing to someone and only 5min after swallowing the powder I noticed something extremely strong coming on. I wrote whoah that. And that was it. The last thing I noticed was a very loud and deep sinus tone. I tried to write this but it was impossible. The next thing I know is that a was looking at my lamp lying on my side but didn't recognized it. So I thought I am in someone else's house and need to get out quick. While trying to get up I I knocked everything over in my room. Somehow I made it outside because I was told that I looked through windows. I think I was put back in my bed by someone where I saw my cat flying and everything looked like my room was rebuild in 18th century style. When I woke up I had cuts and bruises all over my body and my back hurt because I fell down so often. But nothing serious. Please always use a trip sitter on high doses because you basically could think there's something inside you and cut yourself open. Some of my wounds look so clean like done with a knife. Anything could happen. I can't understand how I am alive after this.

 

[Xorkoth]

I'm glad you're still in the land of the living... did this just happen? You might want to check out The Dark Side forum for some support.

 

[norm4n]

15:30: Took 65mg. Talked about acid trips with friends.
17:30: Took another 35mg. Disassociative head space. Feels very dreamy and somehow I feel a connection with my computer. Played some games.
19:15: Took another 35mg. I think this will be the last dose for today. I feel like I'm on Zopiclon. My skin and mouth feels a bit numb and tingly. It feels like a friend of mine sits besides me the whole time. Like she is connected with my left brain. Tears come to my eyes when thinking of it. Very overwhelming but utterly comfortable. I can't imagine how life feels, when beeing sober. Everything is blurry and feels like a dream. There is no sedation. It's fun to move around. Very wonky. Slow, but clear headed. It's not neutral like MXE, it's more of a warm trip. Like the perfect winter drug. I know it's summer. But this day feels like winter. Raining outside, dark room. No lights. Summer's almost gone. Thinking is very abstracted from emotions. Very interesting. Body begins to wobble. Will lay on bed and watch Koyaanisqatsi. Seems like the best thing to do at the moment. Feels like I'm umm at this place when I was 10 years younger. Took zopiclon and weed. I feel like I'm home some kind or like on holidays. Don't know. But something is missing.
21:10 This is a very intense experience. I can't describe it. It also doesn't matter but wow. Spiritual shit. Super nihilistic. I'm so god damn free. Visited my dead grandpa (RIP). Most cleansing experience ever. Existentialism on it's own. Pure fucking god, that's what I am. Floating in fucking heaven man. Never felt this free before. I'm the new born.
21:17 Open minded. Connected to everything. I am the master of this universe. Get this shit.

 

[norm4n]

Can somebody please tell me when I do get sober?

 

[Xorkoth]

Should be a few hours from what I've read. MXP is a pretty long-lasting substance. Don't worry, you'll get there, sounds like you're enjoying it in the meantime.

 

[norm4n]

23:23: Boy. Oh boy. Enjoying is definitely not the right word. I lost my mind completely after feeling like a god. Watched Baraka and wow. This was the most profound experience in my life ever. I'd took a lot of LSD and tryptamines in high doses but this is a whooooole different story. Overfeeding my head. This substance broke many doors wide open. This is really serious stuff. Not a toy. Someone here called it 'happy pill'. It's not. At least for me. That's a really great substance, but I don't know if I'll ever do it again. Not back to baseline, but the peak is over. Wooosh. Will go to sleep now.

In the beginning it felt very silly and hedonistic but than it completely took me off. I don't want to miss this experience though.

Please watch out. MXE is a frozen shithole compared to this This compound is existentialism in it's purity.

 

[Xorkoth]

Very interesting. Seems like people have an even harder time describing diphenidine and MXP than they do describing other dissociatives. I must admit I'm curious, not sure I'll go there though.

 

[Polytoxic]

Thanks for the advise Xorkoth. The main reason was that I was alone for a very long time and my father is dying of cancer, my grandmother is in coma since a few days and I wanted to go with them. I also quit Buprenorphine 2 weeks ago and was coming down from a Methylphenidate/Alcohol binge. Since then I contacted a old friend who finally pulled me out of my hole. I still have to come down from the Flubromazepam. Insane halflife and accumulation. But this one friend who I have not seen for years helps me very much. A real angel on earth. I'm fine now and wont do something that stupid anymore.
Back to topic. It took longer than 5min but the whole trip is very hard to remember. The first thing was the sound in my ears like two huge subwoofers on each side. The numbness was already familiar to me but I was never sucked in the "hole" so fast. The main problem is it doesn't immobilize you like K and you have no control. It's so hard to describe the effects... Or to remember what happened in the time I was "gone". Just remember falling down every time I tried to stand up. Even the next day. It was a very spiritual experience when I came "down" but my there are simply no words to describe this. 120mg produced similar effects. Stick to low doses without a sitter. Things can get out of control very easy but I suffer no bad after effects beside backpain and 110/40 blood pressure and low heart rate the next day
. I will see a doc soon to make a brain image because I survived 100mg Pyrazolam and 200mg Etizolam before.

 

[Ziiirp]

Can somebody please tell me when I do get sober?

You took ~135mg orally. Interpolated from my trials with oral doses (low->70mg), you should not feel completely baseline until 4-5 days after the experience. If you are relatively disso-naive like myself and dosed orally, then you should feel slightly detached/emotionless for a few days after your experiment. I think the substance provides a nice experience but remains in the organism quite too long, particularly when dosed orally (even if that does not make much sense). When I insufflated ~70mg I felt fine the next days. I will try the nasal application again next time and see if I can validate my allegations. Unfortunately my version of the hcl is very coarse-grained and not suitable for this ROA.

Edit :

The main effects sequence for oral doses I would describe as follows :

- 2h comeup (you should not redose in between)
- 3-4h dissociation (for me couch-locking, dreamy)
- 3-4h stimulation (mania)
- 48h-96h after effects (slight detached feeling, potentially dangerous drug interactions)

 

[Methox23]

Anyone else notice how time flies when you're on this stuff?

Took 110mg at 4:30 GMT, orally. Typing feels weird and walking.

My body feels robotic, lol

 

[norm4n]

You took ~135mg orally. Interpolated from my trials with oral doses (low->70mg), you should not feel completely baseline until 4-5 days after the experience. If you are relatively disso-naive like myself and dosed orally, then you should feel slightly detached/emotionless for a few days after your experiment.

Thanks. I'm not used to dissociatives. I try a new one every 3 month, maybe. Today I felt tired, had headaches and am still quite careless. Walking doesn't feel normal and my sight was a bit blurry sometimes. Better than DXM though.

@Methox23: I felt like the white one in the background. But it was more a kind of a mech suite, like in Neon Genesis Evangelion

Maybe next time I use 100mg initial and don't redose for shorter duration.

 

[StreetHalo91]

Can somebody please tell me when I do get sober?

This sums MXP up completely for me tbh. Dosed right, the early/mid parts of the experience feel absolutely incredible for me, like I've taken ket and MDMA at the same time, insane euphoria and wonderfully bizarre feelings. Partway through though this seems to change and the mood becomes much more susceptible to change, sometimes for the worse. If you're prepared for it you can deal with it, but a lot of the time once the initial euphoric rush wears off you'll be willing sobriety... If it felt like the comeup/early period the whole time would be the greatest drug ever... Diphenidine can be similar but because it isn't as initially ridiculously euphoric you get used to the mindset a bit easier so will feel less precarious on it (sometimes lol).

This goes for "lower" doses only btw, high doses of MXP are something completely else and can be awe-inspiring, confusing and/or absolutely terrifying. Second time I took MXP accidentally took a bit too much and thought I'd died and was in some kind of surreal purgatory for hours, one of the strongest and scariest times I've had on any drug ever. Redosing also tends to fuck me up with MXP, usually adds more paranoia and mania at a higher ratio than euphoria and cos of the long come up/come down it's insanely hard to judge correctly. Diphenidine can have similar issues but to nowhere near the same level for me, there's something about that "2-Meo" addition that gives MXP the power to take you further to heaven but also to drag you to further hell in the same session. Though don't get me wrong diphenidine can be proper cray with high doses and redoses too...