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The Big & Dandy Methoxetamine Thread - 5th Dose (you took too much, seriously)

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Who's first for the T-hole? Hehehe. On low doses MXE, i've just to sit in lotus position to instantly find a powerful and peaceful mindset. Does some folk did already notice that meditation increase greatly dissociative s effects? It's sound logical to me but can be some placebo/auto-suggestion...
 
Can anyone recommend me a good starting dosage? I'll be trying MXE for the first time this weekend.

I have no prior K usage but I am pretty experienced with DXM (I weigh about 150lbs and usually took 720-900mg of DXM).

I have no scale so I was going to dissolve 500mg of MXE in 100mg of water, I was thinking about trying 50mg for my first time.

The part that confused me was that erowid list the common range as <50mg and strong as 40mg+, but I read about people consuming 100mg+ at once.

Do you think that 75mg would be too much for a first timer? (I have decent experience with other psychedelics like 2c-e and shrooms). I would prefer a strong MXE trip. I figured 50mg was a decent starting point but seeing as I've read so much about others taking higher doses I'm not sure if I should try 75mg.
 
Can anyone recommend me a good starting dosage? I'll be trying MXE for the first time this weekend.

I have no prior K usage but I am pretty experienced with DXM (I weigh about 150lbs and usually took 720-900mg of DXM).

I have no scale so I was going to dissolve 500mg of MXE in 100mg of water, I was thinking about trying 50mg for my first time.

The part that confused me was that erowid list the common range as <50mg and strong as 40mg+, but I read about people consuming 100mg+ at once.

Do you think that 75mg would be too much for a first timer? (I have decent experience with other psychedelics like 2c-e and shrooms). I would prefer a strong MXE trip. I figured 50mg was a decent starting point but seeing as I've read so much about others taking higher doses I'm not sure if I should try 75mg.

If you are inexperienced with dissociatives then please start low; MXE isn't like psychedelics such as LSD, mushrooms etc and it can feel very weird if you're not used to it. I'd had no previous experience with MXE or ketamine and the first couple of times that I took it I felt seriously fucked up. If you have no tolerance, try 20mg insufflated or sublingual and wait, it takes longer to reach a peak than you'd expect, don't think about redosing for at least 45 minutes. If you do want to go straight into a hole then hit 50mg.
 
If you are inexperienced with dissociatives then please start low; MXE isn't like psychedelics such as LSD, mushrooms etc and it can feel very weird if you're not used to it. I'd had no previous experience with MXE or ketamine and the first couple of times that I took it I felt seriously fucked up. If you have no tolerance, try 20mg insufflated or sublingual and wait, it takes longer to reach a peak than you'd expect, don't think about redosing for at least 45 minutes. If you do want to go straight into a hole then hit 50mg.

Well I'm pretty experienced with DXM. About how long until I peak, an hour after ingesting orally? And why so much advocation for sublingual vs oral?
 
The batch of MXE I have seen peaks in about ~20 minutes for rectal/snorted usage, 40-60 mins for oral, oral/sublingual are roughly the same and rectal/snorted are about 2x "stronger". I've given relative /dis/ newbies ~50mg sublingual and they were fine, but 20-40mg is a good starting place if you prefer lower-dose "stimulant" effects over strong dissociative ataxia. I like high dose DXM/K trips though and so 100mg oral is more my level. You might just have to experiment; starting low is good advice though.
 
75mg oral would be alright for a first time considering the DXM dosages you've done in the past, but i would still recommend starting with 50mg.
 
I've never done over 65mg of MXE... and I'm just fine with that. I started out with 10-15mg doses and it was definitely active. Why not just test the waters? I've always done it sublingually... it doesn't taste bad and it seems to work best for me.
 
yes, threshold is very low, I agree with Erowid's suggestion of 3-5mg. But that doesn't mean that you will experience the full spectrum of effects nor will everyone find that level pleasing.
 
Some of the advice on here is shocking for an Harm Reduction forum. Testing out a new RC with a dose of 75mgs?!

Try an allergy test first, say 5mgs, to see you don't have any bad reactions. After that I'd say start at 20-30mgs and wait half an hour before you redose to see if you like it. MXE isn't for everybody. I enjoy ketamine at doses of 300-400mg with no tollerance (ie straight into a hole), with MXE I find the hole a dark and confusing place most times I end up in it. It also seems to take a whole lot longer to wear off..

The few times I've done massive doses (ie 100mg+) I've found it unpleasant and a bit of a drooler. I just get completely baffled and don't have a clue what's going on, far more trippy than any ketamine aswell. One time when I tried to sleep all I could hear was my mates flatmate creeping about downstairs like a mouse, it felt like I could more myself around the room without physically moving, round the black spots like a grid referrence kind of thing. Then I started thinking I had vangs, could even feel them in my mouth.

Be warned first time, allergy test, then anything above 40mg is high dose to be starting with IMO too much.
 
20mg should be sufficient but im seeing lots of cheaper prices on different areas, so maybe there mxe is cut to i dunno what .
20mg for me is a strong dose
 
im doing allergy test with this stuff probably did between ~7-15mg (eyeballed, dont start i have a lot experience with drugs) and feeling sleeeeepy. i thought mket was more stimulating than K? is this normal?

Update 1: the drip is terrible of this one. added more ~5mg.

Update 2: feeling still quiet sleepy but at same time a bit stimulated. this seems to be more clear headed than K, much better for social interactions possibly partying

Update 3: I dont know yet what yo think of this but since live report is forbidden i will post results later.
 
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Does some folk did already notice that meditation increase greatly dissociative s effects? It's sound logical to me but can be some placebo/auto-suggestion...
It happened to me that I meditated without knowing I'm meditating long before I've started taking any drugs. Yes, it feels quite dissociative without drugs, too.
 
Since I really don't fancy reading through 39 pages.. can someone give me a quick rundown on how mex compares to ket?
 
Comparisons to K

This stuff is definitely comparable to K, its quite similar in many ways but also quite different in ways that are kinda hard to describe. I didn't feel like I was on any other kind of astral plane or anything however there were points where I wasn't really in the room either, the main difference is the opiate effects which brought a real warmth and glow to whole experience. I've tended to stay away from opiates through my life although I've tried most things but I would say a mix of good K and good opium might be a fair comparison.

In terms of strength, its definitely in the same ballpark as really strong K, maybe a little stronger. 50mg looks to my eyes like a decent, although by no means large, sized line (I'm personally a fan more of lots of little lines with K rather than doing one big fatty).

Duration of effects are a bit longer and the onset is a bit slower although not by a great deal. Duration of after effects however are a hell of a lot longer.

No particular feelings of movement that I find with good K, and as mentioned before it didn't seem quite as other-worldly or spiritual as a good K-hole can be (not that I'm the most spiritual person).

The sweaty palms and sweaty feet thing was quite unusual and quite noticeable, a little annoying even but not particularly unpleasant.

http://www.erowid.org/experiences/exp.php?ID=89689
 
I started with little 5-10mg bumps. I liked it a lot.
Then it ran out and I got a gram to myself. I've been enjoying that one a bit too much. Doing higher dosages just because I can. I love this stuff.

I've quit all my other drugs for it. I was trying not to do it after semi holing, but it helps me so much that I don't wanna stop!
 
Don't mean to be a bummer but I have read that ketamine and, presumably, MXE can cause some serious bladder/urinary tract problems.

"Abstract
OBJECTIVE:

To report the clinical spectrum seen in young abusers of street-ketamine (regular recreational abusers of street-ketamine, for its hallucinogenic effects) in Hong Kong, presenting with significant lower urinary tract symptoms (LUTS) but with no evidence of bacterial infection.
PATIENTS AND METHODS:

We retrospectively analysed the clinical presentations, pelvic pain and urgency/frequency scores, video-urodynamic studies, cystoscopy findings, histological features of bladder biopsies and radiological findings of 59 ketamine abusers who were referred to the urology units of Princess Margaret and Tuen Mun Hospital, Hong Kong, from March 2000 to December 2007.
RESULTS:

Of the 59 patients, all had moderate to severe LUTS, i.e. frequency, urgency, dysuria, urge incontinence and occasionally painful haematuria. Forty-two (71%) patients had a cystoscopy that showed various degrees of epithelial inflammation similar to that seen in chronic interstitial cystitis. All of 12 available bladder biopsies had histological features resembling those of interstitial cystitis. Urodynamically, either detrusor overactivity or decreased bladder compliance with or without vesico-ureteric reflux was detected to some degree in all of 47 patients. Thirty patients (51%) had unilateral or bilateral hydronephrosis on renal ultrasonography, and four (7%) showed features suggestive of papillary necrosis on radiological imaging. Eight patients had a raised serum creatinine level.
CONCLUSION:

A syndrome of cystitis and contracted bladder can be associated with street-ketamine abuse. Secondary renal damage can occur in severe cases which might be irreversible, rendering patients dependent on dialysis. The present data do not establish the precise cause nor the incidence. Street-ketamine abuse is not only a drug problem, but might be associated with a serious urological condition causing a significant burden to healthcare resources."
http://www.ncbi.nlm.nih.gov/pubmed/18680495

So although user reports all sound nice, don't go nuts with this stuff or you may regret it for like the rest of your life. Just saying.
 
Don't mean to be a bummer but I have read that ketamine and, presumably, MXE can cause some serious bladder/urinary tract problems.

"Abstract
OBJECTIVE:

To report the clinical spectrum seen in young abusers of street-ketamine (regular recreational abusers of street-ketamine, for its hallucinogenic effects) in Hong Kong, presenting with significant lower urinary tract symptoms (LUTS) but with no evidence of bacterial infection.
PATIENTS AND METHODS:

We retrospectively analysed the clinical presentations, pelvic pain and urgency/frequency scores, video-urodynamic studies, cystoscopy findings, histological features of bladder biopsies and radiological findings of 59 ketamine abusers who were referred to the urology units of Princess Margaret and Tuen Mun Hospital, Hong Kong, from March 2000 to December 2007.
RESULTS:

Of the 59 patients, all had moderate to severe LUTS, i.e. frequency, urgency, dysuria, urge incontinence and occasionally painful haematuria. Forty-two (71%) patients had a cystoscopy that showed various degrees of epithelial inflammation similar to that seen in chronic interstitial cystitis. All of 12 available bladder biopsies had histological features resembling those of interstitial cystitis. Urodynamically, either detrusor overactivity or decreased bladder compliance with or without vesico-ureteric reflux was detected to some degree in all of 47 patients. Thirty patients (51%) had unilateral or bilateral hydronephrosis on renal ultrasonography, and four (7%) showed features suggestive of papillary necrosis on radiological imaging. Eight patients had a raised serum creatinine level.
CONCLUSION:

A syndrome of cystitis and contracted bladder can be associated with street-ketamine abuse. Secondary renal damage can occur in severe cases which might be irreversible, rendering patients dependent on dialysis. The present data do not establish the precise cause nor the incidence. Street-ketamine abuse is not only a drug problem, but might be associated with a serious urological condition causing a significant burden to healthcare resources."
http://www.ncbi.nlm.nih.gov/pubmed/18680495

So although user reports all sound nice, don't go nuts with this stuff or you may regret it for like the rest of your life. Just saying.

"Methoxetamine is a product of rational drug design: its N-ethyl group was chosen to increase potency, lessening the risk of interstitial cystitis that can result from the accumulation of ketamine-like metabolites in the urinary bladder."

--

Not had it for a week, I plan to dose on Monday so I will have had a 10 day break. I'm seriously hoping tolerance will have fallen a bit? Will it?
 
^^^ it might have, or it might not have. in fact it might seem like your tolerance has gone up even. dissociative tolerance can take a long time to go away.
 
I suggest if it is your first time and you are wondering what dose to take, to take a small dose like 20mg. You can always wait half an hour or an hour and take more. You won't have built a tolerance at all after a single dose (or even several doses).

Why dive in all the way into uncharted waters when you can get your feet wet first?

20mg + 20mg + 20mg of MXE spread half an hour apart or so is just as much fun as 60mg taken all at once. Don't sweat it :)
 
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