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The Big & Dandy Methoxetamine Thread - 4th Dose (don't overdose)

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I can relate 100% to everything you've said, which makes me feel less alone. :)

I too have suffered 2 panic attacks on MXE, it's extremely unpleasant when you get into a mindset that something is wrong with your body, yet due to MXE's effects everything feels alien and weird, adding to the panic

And yes, when i first discovered MXE and was abusing it daily, I never even got a twinge of craving for another drug, even when I went out on low doses of MXE I'd avoid alcohol. And it wasn't just the drugs I no longer craved, it was bad habits of mine, instead I craved good habits and to get everything in my life into order. during the first month of using MXE I was certain that I found some sort of miracle cure for many of my problems. Eventually those habits returned and MXE was making me lazier than ever...

MXE has to be one of the most fascinating experiences available, but not always enjoyable...

I had a very mild panic attack my first time taking MXE (closer to mania) and took a bit of xanax which stopped it.

I can also relate to the idea of not wanting to do other drugs. I had been using kratom about 4 days per week for a few months before taking MXE, but after my first MXE experience my desire to take it was eliminated. I've also smoked considerably less cannabis since since I started using MXE, and almost every time I've gone out in the last month I've used MXE instead of something else...

I'm keeping my usage in check as I'd like to prolong the 'honeymoon' is much as possible, but so far the most drastic and long lasting benefits I saw were after my first dose.
 
I can relate 100% to everything you've said, which makes me feel less alone. :)

I too have suffered 2 panic attacks on MXE, it's extremely unpleasant when you get into a mindset that something is wrong with your body, yet due to MXE's effects everything feels alien and weird, adding to the panic

And yes, when i first discovered MXE and was abusing it daily, I never even got a twinge of craving for another drug, even when I went out on low doses of MXE I'd avoid alcohol. And it wasn't just the drugs I no longer craved, it was bad habits of mine, instead I craved good habits and to get everything in my life into order. during the first month of using MXE I was certain that I found some sort of miracle cure for many of my problems. Eventually those habits returned and MXE was making me lazier than ever...

MXE has to be one of the most fascinating experiences available, but not always enjoyable...

I think that in the end, MXE will always leave a user worse off than before they started using it, if they use it enough. Same story with any drug of abuse. I can't say the positives I've gleaned from MXE outweigh the negatives it has caused.

I began to get those cold, unpleasant experiences from about 2 weeks into my use, and I would assume that I was never going to have fun with MXE again, but then an absolutely monumental trip would blow my mind and I'd fall in love all over again.

The trips I had more recently were are a world apart from the ones I used to experience back in december. They got heavier, sicklier, and generally less lucid. The way my body responds to methoxetamine appears to have noticeably altered since december.
 
I can relate 100% to everything you've said, which makes me feel less alone. :)

I too have suffered 2 panic attacks on MXE, it's extremely unpleasant when you get into a mindset that something is wrong with your body, yet due to MXE's effects everything feels alien and weird, adding to the panic

And yes, when i first discovered MXE and was abusing it daily, I never even got a twinge of craving for another drug, even when I went out on low doses of MXE I'd avoid alcohol. And it wasn't just the drugs I no longer craved, it was bad habits of mine, instead I craved good habits and to get everything in my life into order. during the first month of using MXE I was certain that I found some sort of miracle cure for many of my problems. Eventually those habits returned and MXE was making me lazier than ever...

MXE has to be one of the most fascinating experiences available, but not always enjoyable...

When I started taking it daily I thought it was amazing. It cured my depression, gave me energy and motivation to do stuff and just generally took me away from my problems. All of this has gone now. It just makes me have bad thoughts now. I know I was abusing the stuff but kept taking it anyway hoping that magical trip would come again. Strange thing is that it did, but it's not worth the cold, isolated feeling I got for so long.

The panic attacks I got lasted for about 2-3 minutes. Very scary stuff. I thought I'd screwed my brain. I did not suffer that on a high dose by the way. Just a few small doses through the day triggered them.

You're not alone mate. I'm guessing there are plenty more people out there experiencing something similar.

Using this substance once a month would be fine I think. By using it say 2-3 times a week you're going to have problems. I just have an addictive personalty and have been abusing a substance that we don't know much about.
 
I can't help but feel that I am missing something with MXE..
At low doses (10-20mg up the nose) it felt ok, like dirty ketamine but not as fun as ketamine at all. Tried this maybe 3 or 4 times.
At higher doses (45-60mg up the nose) I felt like shit, dark images and general dysphoria to be honest. Mindfuck and depression. Not fun, recreational, spiritual or teaching in anyway to me. Whereas ketamine (although I don't use it very often any more) can be all these things dose dependant.

I got a gram in december 2010 and all my experiences were from this gram, has the quality/purity changed since then? Any advice for other ROA or anything else that maybe I am missing? If not I guess its not for me and I'll stick to the true Psychs and K :p
 
Just want to pose another time the question of the smokeability or the aptitude to vaporize this compound.
Tried few mgs by myself some time ago, but 1) it were 5mg max. and 2) I wasn't really sober beforehand.

Am really interested in any information on this; dosage, time course of the experience (if there was any), general quality of the experience - also by comparison with the other ROAs -, chemical know-how inspired "vapeing MXE is generally im-/possible because ..." ... and so on and so forth :)

o/
 
B) Methoxetamine appears to exert most of its dissociative potential during the first 3 hours after its administration, and the remainder of its duration of action seems to be dominated by its properties as a dopamine reuptake inhibitor. Why exactly this is the case is not well understood.
its such a bizarre duality. impresses me every time.
Does 3-meo-PCE or any other related compound act the same? Can't say i've tried any but I had assumed 3-meo-pce at least would also produce residual stimulation.

also, is there a significant amount of evidence that ketamine and/or other arycyclohexylamines act as DRIs then? There is no citation for that statement on their wiki...
in my mind DRI activity would account for the way the mania/stimulation seems to build over time but thats purely a guess from me.


also, for those saying they don't know if they actually like it, i agree that i only enjoy lowerish (<45 mg) oral doses, but i had chalked this up to me not actaully like dissociatives that much. guess i'll have to try ket before i can say for sure!
 
I've done mxe at low and high dosages via oral, sublingual, and insuffilated routes.

With a decent tolerance, just did 40mg rectal and the results were amazing! The intensity, rush, and onset all seemed like it was my first time doing it (which was sublingual btw).
 
Well I went though a gram of this stuff in a week8o
(Not recommended)

I guess I passed some sort of test to prove that I am somewhat mentally stable? Because there were definitely some points where I thought I was either going to end up dead or in a nut house. But I stayed strong and embraced what this chemical had to share with me

It is a beautiful drug, I have learned so much from it, and now that it is it all gone I am ready to begin an entire new life:) I have never felt more optimistic about my future than I do now.

Throughout the entire week I kept assuring myself that this is exactly what I NEED. There were faithful moments where I did in fact believe that there was a god and he was so proud of me for allowing him to share the unknown with me. There was not a single moment of regret throughout the whole experience,brain damage didn't even cross my mind,(I thought what is the worst that can happen, death? If that is the case i'll take it, because the experience itself was worth the price of admission and I was ready to go.

I was convinced that thousands of years before my time there were shamans who used this daily, years on end. I was extremely ravenous to what this chemical had to teach me and couldn't just look away.

I am going to take a few weeks break with this stuff, but I will be back, I crave even more of the unknown.

Well, that's the best I can do, i'm really not one who can share specific moments and emotions that were revealed along the way.
 
Just to add my experience: i've combined MXE (in doses up to 50 mg nasal) with mdma, amt, 6-apb and 5-apb lots of times and never had any noticeable negative effects (only positive ones). (this is not to discount anyone else's negative experience of course; just to add my anecdotal data)

As i would with k, the mxe was always taken AFTER the stim's peak started to subside (with 6/5-apb, at least 6-8 hours after taking). I personally find (as with k) that i much prefer mxe after some serotonergic substance - i like mxe on it's own, but i find it misses some of the magic (not to mention visuals) i get when i take it after the abovementioned substances (or with serotonin agonists for that matter). I also find that the mxe helps me to not carry on with the mdx/6/5-apb for another night (as i usually might) by giving a sort of 'closure' to the experience. I also find it seems to temper the 'comedown' from the stims later in the week (this might be illusory - as might everything else i've written here)

I should say that i worked up to these combos from v. small doses, and i always reduce the amount of each substance i would take when combining (and NEVER take them at the same time). I wouldn't recommend anyone else combining mxe with anything without working their way up from baby doses of each to see if they get dodgy reactions (but try not to expect dodgy reactions while on it or you may make them happen: noone i know who has combined carefully has had one, so a lot of people seem to be fine with it).

This substance can certainly cause uncomfortable experiences if dosed haphazardly; but i've found that as i've got used to what each dosage roughly does and how long it lasts, and make sure i prepare my set/setting beforehand, i only get positive experiences - ymmv

Disclaimer: i suppose i should say positive experience is different for everybody - people who've never come close to ego-loss on another substance (i'm talking to you, putative, possibly mythical "meph-kidz") might not like it when they get it on high-dose mxe; though it's usually a bit less traumatic than tryptamines, it can still be ego-loss. If you don't want ego-death, keep your doses below ~50mg (though i've not really had significant depersonalisation from less than 70mgs - ymmv). If you do want ego-death, make sure you're somewhere you feel safe, with no repercussions possible if you start barking like a dog or crying for your mammy for a few hours.

Plus (as with any psychedelic) be very careful about giving this to people who may have had psychoses in the past (or if you have) - i know of one person with such a history who had to be admitted to a psych ward after too much mxe (not given by me i hasten to add)


/To answer another question above: 3-meo-pce does have siginificant stimulation all the way through (and 3-meo-pcp has even more - based on not many trials): in general they both feel more stimulated(/manic?) than mxe to me - also, both leave you a bit more physically drained and have a longer afterglow (half-life?) than mxe (up to 2 days - this is really nice, but can be inconvenient if you need to do stuff) - i guess the ketone in the mxe reduces the half-life (as with k?). Also, it seems that the 3-meo group common to them all may have something to do with the 'transcendence' that some people report (judging by the flimsy basis of a single report from someone who said that 3-meo-pcp somehow felt more 'transcendent' than straight pcp /anotherdisclaimer: - this is just forum-based speculation; i'm obvioulsy not a scy-un-tist
 
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Not that I'm proud of it or anything, just putting the information out there but I've been taking 40-60mg (plugged) of MXE daily for a little over half a month now with no negative repercussions that I can find other than the occasional time when I took it while I was feeling not so great (tired or sluggish or whatever) and it just exacerbated those feelings while I was on it.

Not the smartest thing to do but meh. I'm off it now for at least another month.
 
I am going to take a few weeks break with this stuff, but I will be back, I crave even more of the unknown.

Be carefull with that.

I really think that you should begin to change your life as you wanted, while you have the momentum. Maybe you are in the midst of it, I don't know, but do it! No waiting allowed :)
 
Is this stuff getting cheaper? I ask as i've seen sites selling it alot cheaper recently, or will this cheap stuff be rubbish?

If anyone can give me the 'normal' price for 250mg, 500mg, 1g etc... (i'm not asking for sources)
 
Read the forum guidelines:
No discussing quality, availability or price: This is related to the 'no sources' rule. NONE of this stuff is our business, and none of it is "bluelight material." Quality, availability and price are all about acquiring drugs, which is a topic we do not discuss here.
 
Thankyou so much for taking the time to share your thoughts and information with us, NeuroPsyence. Are you someone who is personally tied to the studies you mention that are taking place? These sorts of studies could provide a missing link, and certainly clear up a lot of issues in my mind. Your posts are somewhat reassuring & comforting for me <3

I am not personally tied to the studies I mentioned, but some of my colleagues are affiliated with the organization that is conducting them. I know one of the researchers who is actively working on this as well. The existence of adverse reactions related to dopamine is a topic that interests me, and I will be checking up on their progress periodically, but it is not likely that I will be able to share much information about the studies until 2012.

I got a gram in december 2010 and all my experiences were from this gram, has the quality/purity changed since then? Any advice for other ROA or anything else that maybe I am missing? If not I guess its not for me and I'll stick to the true Psychs and K :p

The purity has improved since the first commercial batches of the drug were synthesized. I recently came across a sample that tested 99.7% purity via NMR spectrographic analysis, which is a notable improvement over what was initially available after MXE hit the UK market. However, the subjective nature of your experience with the drug would likely not be any different with the higher purity chemical (unless what you initially got in december was tiletamine, which was marketed as MXE by several vendors after the drug's initial explosion in popularity. Edit: I just remembered, we actually got a couple of reports from people who had been sold a mixture of dextromethorphan powder and a rare and highly potent arylcyclohexylamine derivative as methoxetamine as well, so I suppose this is also a possibility).
 
Not that I'm proud of it or anything, just putting the information out there but I've been taking 40-60mg (plugged) of MXE daily for a little over half a month now with no negative repercussions that I can find other than the occasional time when I took it while I was feeling not so great (tired or sluggish or whatever) and it just exacerbated those feelings while I was on it.

Not the smartest thing to do but meh. I'm off it now for at least another month.

How were you able to consistently take the same dosage every day?

The few times I have used it consecutively days in a row I always had to up the dosage to get the same effects...
 
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