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☛ Official ☚ The Big & Dandy Methoxetamine / MXE Thread - Part 17 - South-Kansas is going bye-bye

I missed the boat on this I was off Dissociatives for a while.

Probably a good thing I can't handle Dissociatives. I just went off the rails on a crazy train with 3-meo-pcp and flushed it.

This one sounds better I like putting drugs up my nose for a rush, 3-meo didn't have that really. Probably would have ended up in a padded cell, straight jacketed wavy.
 
Help?!?! said:
Yeah, that's definitely true. I'll never get over that strange loveliness it provides though, truly top tier.
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In a number of ways it has the capacity to set off spirit-mind-body reactions that produce some of the strongest love-esque energies I ever experienced. A single signal that comes from a pure place in the heart can seem to open the floodgates in a sense, and cascade into a river of outpouring of energy originating from that inital spark, manifesting as overwhelming empathy, or a buzz, or a complete unbounded receptivity to music, or a resonance of neurons ensembles firing, or some sort of pendulum of oscillating energy at various harmonics, among other possibilities for example.
 
^ Seems very interesting, but is there a way to access the full text without paying? If not, would you mind sharing the bits that were of interest to you?

BTW, lol at the 2d line of the highlights: "40 mg/kg MXE had sedative effects." No shit, those poor rats were indeed duly stratospherised in the name of science =D
 
Sure, here is the full text. Professional researchers could distill this for laymen better than myself. For instance, I was trying to figure out what they were saying in the pre-pulse inhibition section...but they were using too many big words...could be they were simply confirming psychomimetic effect, but I think it was more nuanced than that.

Some things I noted:
It provides a handy flowchart that shows the stages of MXE metabolism into different metabolites, and a graph that shows the concentration of the different metabolites in the blood for the 3 dose levels. MXE's main metabolites, normethoxetamine O-desmethyl-MXE appeared in the brain at about 10x lower than MXE itself. The pharmacology of these metabolites have not been studied, but it is unlikely to be relevent at such low concentrations. By contrast, norketamine, (a primary ketamine metabolite) exceeds brain levels of ketamine and therefore contributes significantly to its pharmacology. One interesting thing noted is that they found metabolism differences between the rats and humans, and concluded 'it is plausible that different isoenzymes at CYP450 are involved in the rat metabolism compared to humans.

The referenced research articles pointed out a few new interesting articles I had not read, for instance http://journals.lww.com/behavioural...analogue_methoxetamine_generalizes_to.16.aspx

Reading about 'homogenising' rodent brains was interesting...

Overall it puts a lot together and seems rigorously-conducted (as far as a peon can gather). The result is some new data sets as well as affirmations of previous research and users reports.
 
Cool, thanks :)

Seems those rats are some hard headed creatures: they need 30mg/kg of Ketamine to merely start robowalking! It does indeed seem difficult to project those results on humans, seeing how their body handle drugs differently. Anyhow, there's no lack of human volunteers if need be =D
 
When in god's name is this beautiful bastard of a chemical going to be available again? Nothing else compares to it and the days have turned to weeks and now into months and months of waiting, waiting, hoping one day to see an announcement of a new (and quality) batch. How can something so amazing just vanish with no sign of return? It doesn't make sense.
 
send said:
When in god's name is this beautiful bastard of a chemical going to be available again? Nothing else compares to it and the days have turned to weeks and now into months and months of waiting, waiting, hoping one day to see an announcement of a new (and quality) batch. How can something so amazing just vanish with no sign of return? It doesn't make sense.
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Well, it has happened in the past to some quality substances and the chems never came back to the availability as in preban days. Good luck trying to score some 2C-I, mephedrone or bk-MDMA, for example. Just forget about this one and move on. There are some amazing dissociatives right now, 3-MeO-PCP, 3-MeO-PCE, 2-OxO-PCE, 2-OxO-PCM, ephenidine, diphenidine, MXP, 2-fl-ketamine, ketamine itself... I don't miss my MXE at all ;)
 
send said:
When in god's name is this beautiful bastard of a chemical going to be available again? Nothing else compares to it and the days have turned to weeks and now into months and months of waiting, waiting, hoping one day to see an announcement of a new (and quality) batch. How can something so amazing just vanish with no sign of return? It doesn't make sense.
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It's wise to stock up on chemicals that are truly extrordinary because who knows when they won't be available anymore. Or when your country passes some draconian blanket drug law (England).
I hope we do see a return of MXE but I don't think it would be anything but very small scale and you'd have to know those people.
I think it'll become like synthetic mescaline. It'll be around but it'll be rare.
 
MSK said:
Good luck trying to score some 2C-I, mephedrone or bk-MDMA, for example.
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the difference there is those were all made Schedule 1 in the US. not sure on 2C-I in the EU but i believe mephedrone and bk-MDMA are both outright banned over there?

MXE isn't banned in the US. the recent drought is just due to lack of supply, since the countries we got it from mostly banned the stuff themselves.

all its going to take is a decent lab in some other third world country to see the market opening and we will yet again see kilos of MXE coming through the american borders.
 
You can get all of those if you know where to look for them. bk-MDMA just became tougher to find due to legality reasons, as you may know MSK, but that batch will still find it's way to customers for sure. There was some MXE on the darknet, EU-only, but its gone now. It will reappear sometime, however.
 
MSK said:
Well, it has happened in the past to some quality substances and the chems never came back to the availability as in preban days. Good luck trying to score some 2C-I, mephedrone or bk-MDMA, for example. Just forget about this one and move on. There are some amazing dissociatives right now, 3-MeO-PCP, 3-MeO-PCE, 2-OxO-PCE, 2-OxO-PCM, ephenidine, diphenidine, MXP, 2-fl-ketamine, ketamine itself... I don't miss my MXE at all ;)
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Hombre MSK, una alegria verte por aquí.

Un saludo compadre.;)
 
kidklmx said:
You can get all of those if you know where to look for them. bk-MDMA just became tougher to find due to legality reasons, as you may know MSK, but that batch will still find it's way to customers for sure. There was some MXE on the darknet, EU-only, but its gone now. It will reappear sometime, however.
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Of course, I've got no problem sourcing those... but you get my point. Now you need to do hard work for sourcing any of those, and MXE on the deepweb has decreased purity and multiplied prices x3, so... I don't expect a good future for this one.

Saludos veodo! PM who you are, as I don't recognize that nickname you are using xP
 
Yeah I know, its gonna become a novelty compound, not really for daily use or whatever, but its gonna be around. The way this gained popularity, it would be strange if no one would make it.
 
kidklmx said:
Yeah I know, its gonna become a novelty compound, not really for daily use or whatever, but its gonna be around. The way this gained popularity, it would be strange if no one would make it.
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It really would be IMO. MXE is still legal in various places so it's really like TNW put it, finding a new chemical company in a new company willing to do the work! All that would really need to happen(which it probably will, MXE is nearly as popular as ketamine now a days while only being around for 8 or 9 years)is for a few vendors to get a couple to a few kilos each and the game would be back on! Even if it never really surfaces again that openly, it'd be so hard for me to believe it wouldn't go more underground, and sell like that.
 
Help?!?! said:
It really would be IMO. MXE is still legal in various places so it's really like TNW put it, finding a new chemical company in a new company willing to do the work! All that would really need to happen(which it probably will, MXE is nearly as popular as ketamine now a days while only being around for 8 or 9 years)is for a few vendors to get a couple to a few kilos each and the game would be back on! Even if it never really surfaces again that openly, it'd be so hard for me to believe it wouldn't go more underground, and sell like that.
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I'm praying every night for this to happen, even when there is no God... But I doubt it will came back, if it didn't by now. Suppliers are making a lot of money with other novel dissociatives, they won't bother on making a lab on a foreign country where MXE is not banned, I don't see it!
 
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