Yeah I did 40mg oral and then 20mg rectal 40 minutes later, and laid down with good headphones and music, on my bed, and went the furthest out I've probably ever been, it was the most amazing dissociative hole of my life by far. I've had 85mg orally, on mescaline, with my friend while camping, and it was wild, and beautiful and amazing, but it wasn't into hole territory at all. I had 100mg orally once (in 4 doses) with friends and I felt hole-like sensations but it was too much for me and just caused issue... until I laid down with my eyes closed, and then I just existed in this perfect, beautiful, slowly rotating place of bliss.