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The Big & Dandy Medication/Supplement Interaction Thread

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I think I might experiment with small doses of n,n dmt one evening.

I'll stay of moclobemide for 48h and then during the evening I'll build up the dosage until the effect is good.

I'll work like this : 5 mg - 7.5 mg - 10 mg - 15 mg - 20 mg - 22.5 mg - 25 mg.

With leaving about half an hour between every attempt.

What would be a good time to leave between my lost hit of n,n dmt and my first dosage of moclobemide? Somewhere around 30h ?


I'll post my exerpiences ... but it could take a while before I'll start with it.

If it works out fine I'll try a modest dosage of 4-aco-mipt.
 
wolvenkind said:
I think I might experiment with small doses of n,n dmt one evening.

I'll stay of moclobemide for 48h and then during the evening I'll build up the dosage until the effect is good.

I'll work like this : 5 mg - 7.5 mg - 10 mg - 15 mg - 20 mg - 22.5 mg - 25 mg.

With leaving about half an hour between every attempt.

What would be a good time to leave between my lost hit of n,n dmt and my first dosage of moclobemide? Somewhere around 30h ?


I'll post my exerpiences ... but it could take a while before I'll start with it.

If it works out fine I'll try a modest dosage of 4-aco-mipt.
Click to expand...

i would smoke dmt as moclobemide is coming up, if it were me, since the two make a good synergy. i've never used dmt without an maoi though, so i wouldnt know if it would be better or worse without it.

if you wanted to wait until moclobemide was not going to interfere, i would just wait about 10 hours after your last moclo dose. and then i would dose with moclo whenever your trip was done.

it's possible that since you've been on a serotonergic antidepressant, that your response to psychedelics will be diminished. if this is the case, ie, if you find out that psychs dont work as well for you off of moclobemide, i would recommend just staying on moclobemide, since it would in theory help to reverse your built up tolerance. some people dont get this tolerance building effect from antidepressants though, so, your mileage may vary.

i dont know about what dosage to use in what order, as ive never smoked dmt, but you might want to look in the big and dandy smoked dmt thread.
 
Hi,

I mostly smoke about 30 mg in a bong. But since I need only little dextro-amphetamine I'm gonna try very low, just to be sure and leave intervals between next hits and climbing up.

n,n DMT seems a good starter for my experiments since it's short, a short half-life and I'm very familiar with the feeling and it's gentle.

I have no urge for pharmahuasca, I actually want to do it with moclobemide as much out of my system if possible. First start with that, before 'potential' further experiments. Which could be pharmahuasca ofcourse.

I ingested clonidine about half an hour ago btw, haven't had moclobemide in 24h, it's doing his work. Until now i tried on moclobemide: Methaqualone, methylamphetamine, dextro-amphetamine, modafinil, ghb, gbl, 1,4 bdo, nitrous, hashish, ketamine, mdma, zoldipem, lorazepam, bromazepam. And now = clonidine .

So I might try soon: barbital, n,n dmt and later on 4-aco-mipt and 4-aco-dmt (or just shrooms) in low dosages.

I'll keep you guys informed.
 
Never tried LSD so I dont think I can be of much help. But that Accutane I was on and it did horrible things to me mentally. It did kind of clear up my acne though. I took it years n years ago. Please be carefull with that drug. And follow up on your blood samples often to check n see if it is doing anything to you.
 
I know nothing specifically, but accutane is serious shit. I would tread very carefully.
 
Accutane did wonders for my acne (pretty much completely gone now) but it did make me feel horrid while I was taking it and for many months afterward. I did take LSD once during the course of my treatment and there were no interactions, nor would I expect there to be any. However, pay heed to the set you're in before the trip - if Accutane makes you feel yuck, then psychedelic + Accutane has the possibillity of making you feel terrible, terrible.
 
feelgoodhit said:
i would not want to be tripping with my skin all dry & fucked up like i hear accutane does.
Click to expand...
True, when I'm trippin, holding a ciggaret in my mouth feels really weird, so if my skin was all dry and shit, it'd freak me out.
 
i've taken lsd and accutane, but not at the same time.

lsd made me mentally ill or at the very least brought out a latent mental illness. it was fun before that happened.

accutane cured me of very severe treatment resistant acne, side effects being dry skin etc. no recreational value in accutane.

if given a choice, take accutane. or both.
 
Cipralex and AMT

Evening

Are there any known problems with taking Cipralex (SSRI) and AMT (~30mg)

Dose AMT work on the serotonin reseptors at all?

Thanks
 
:(

What about LSA? I see LSD is ok, are they similar enough? sorry for my ignorance.
 
SSRI's and LSA's?

Is there any danger in being on SSRI's(luvox specifically) and taking HBW seeds or MG seeds? Ive done LSD on these meds with no problems but im not sure if LSD is even closely related to LSA's...Any experiences?

BTW it sucks not being able to take ecstacy.
 
LSA's are related to LSD (both drugs belong to a class called Ergolines; for more info read Shulgin's TIHKAL entry on LSD) and just like LSD's effects are weakened and dulled by SSRI's I imagine the same thing would happen if you took LSA containing seeds while on an SSRI. I used to trip while on SSRI antidepressants and it made tripping pretty pointless. I'd still get visuals but barely any interesting mental effects at all. This thread should be moved to the Big and Dandy LSA Thread.
 
About a week ago, I plugged 48mg of MDMA about 45min after taking a high dose of melatonin, I think it was 21mg. The effects were stronger than a 150mg oral dose. I had also drank a small amount of wine. It felt like I was tripping on a stronger psychedelic and the visuals were pretty strong. Lots of sound distortion too. I had few visuals from a 150mg oral dose. I was caught off guard by the intensity, and found it frightening at first. There were no significant side effects, and I felt great during and after the trip.

I know plugging increases the effects, but I would not expect that much of an increase. Does anyone know if melatonin can potentiate the effects of MDMA?
 
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