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Dissociatives The Big & Dandy Eticyclidone / 2‘-Oxo-PCE Thread

I had 22mg sublingual last friday and my trip went 3 hours pretty intense and after all the after effects were lasting up to 16 hours. Don't think IM is the way to go, even nasal is not anything better than my sublingual trip. Only vaping is a form on it's own, it's intense and short, but nothing you can really work with. IMHO
 
Please elaborate on the stevens johnson syndrome? Is this bc o pce could possibly have anti biotic properties and that can be a cause of it?
 
The Steve-Johnson Syndrome is a T-Cell mediated overreaction on some drugs and causes necrosis of skin and mucosa. It is not directly linked to an antibiotic effect, despite some antibiotics can cause a Steve-Johnson Syndrome. For example some NSAR or Allopurinol can induce it.
 
I did relatively heavy testing when I had tried it and I found no reaction. Dosages of 60+ over 24 hour periods for three day trials. I feel as if something T-cell related would have popped up when I had a blood draw shortly after.
 
can anyone comment on the energy level you feel while on this one? for me, i find MXE to be fairly energetic, ketamine to be more sedating but still some energy there, and then deschloroketamine (2-oxo-pcm) is pretty sedating and i just want to sit around. i'm wondering where 2-oxo-pce compares.
 
Energy level is lifted. But health concerns leave it sedating, in a body load-type way. Want to get up and move around but discouraged by signs and symptoms of high blood pressure. Stevens-Johnson is of concern due to previous commenters' signs and symtoms.

SMG, what T-cell related test do you think may have been relevant? What test did you do?
 
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ManRider said:
can anyone comment on the energy level you feel while on this one? for me, i find MXE to be fairly energetic, ketamine to be more sedating but still some energy there, and then deschloroketamine (2-oxo-pcm) is pretty sedating and i just want to sit around. i'm wondering where 2-oxo-pce compares.
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Found it to be fairly similar to MXE, with a slightly clearer head
 
Really liking this one.

Massive user of Mxe when it was about and used it in varying degrees functionally on a day to day basis and a lot deeper when I had the opportunity.
Not pushed this past the 10mg mark but build up on several 10mg doses over the course of the night.
Really nice, like Mxe you never really know what you’re going to get i.e. sometimes very stimulating other times sedating.

None the less really warm and has those Mxe moments where you’re thinking just seems to all click into place and ‘you get it’ type thing.
On the flip side of that couple of confusing stages last night where my brain felt a bit mongy but I’d had a couple of drinks some benzo’s towards the end of the evening.
Also goes great with weed and a couple of beers.

Feel great today after last night’s experiment but slightly detached emotionally for some reason.
Anyway very functional at lose doses which is great for those of us that need to fly under the radar.
 
I'm used to sticking to smaller forums, but I thought i'd add my 2cents:

[FONT=Calibri, sans-serif]Substance:[/FONT][FONT=Calibri, sans-serif]O-PCE
[/FONT][FONT=Calibri, sans-serif]R.O.A:[/FONT][FONT=Calibri, sans-serif]Insulffated,IM
[/FONT][FONT=Calibri, sans-serif]Person:[/FONT][FONT=Calibri, sans-serif]25/M,[/FONT][FONT=Calibri, sans-serif]Height:[/FONT][FONT=Calibri, sans-serif]5'9 (175cm),[/FONT][FONT=Calibri, sans-serif]Weight[/FONT][FONT=Calibri, sans-serif]:11stone (69.5kg, 152lbs)
[/FONT][FONT=Calibri, sans-serif]Setting:[/FONT][FONT=Calibri, sans-serif]My bedroom, Night, Everyone else has gone to bed.

[/FONT][FONT=Calibri, sans-serif]MindSet: [/FONT][FONT=Calibri, sans-serif]Excited,i've been looking forward to a new dissociative to hit the marketsince the MXE ban, and I managed to get a 30mg free sample of thisfrom a reputable vendor.

[/FONT][FONT=Calibri, sans-serif]Pre-Trip
[/FONT][FONT=Calibri, sans-serif]It'sabout 23:00 and after finishing work, eating and doing some choresi'm finally ready to give this promising new dissociative a go! I'vegot a fair amount of experience with Ketamine, MXE and 3-Meo-Pcp viaa variety of ROA's but held back from ordering any of the most recentdissociatives which hit the market (namely the diphenidine family)cause I didn't hear many good things about any one of (infact, mostof the reports seemed to be pretty negative!).

Since Ketaminehas been varying a lot in quality and price in the UK, andMethoxetamine was banned in the EU last year I've been waiting foranother decent quality dissociative to hit the market. When I heardthe first few reports of O-PCE I was definitely excited, but at theprices it's currently selling at I couldn't warrant the cash toactually buy a decent amount, luckily my a reputable vendor sent me a30mg sample. Although I new it was meant to be potent, I can't say Iwas expecting to feel much from 30mg!)

I'd been up all theprevious night after having a couple of doses of speed the nightbefore, so was quite tired. This may be why it hit me sohard.

[/FONT][FONT=Calibri, sans-serif]T+0:00[/FONT][FONT=Calibri, sans-serif]– I read a few reports saying to start at a dose of around 5-10mgon BL, but I stick to smaller forums and a member I trust thererecommended at least 20-30mg, so I weighed out a line of about 15mg.I contemplated doing an allergy test since this stuff is so new...but couldn't wait. I snorted the line.

[/FONT][FONT=Calibri, sans-serif]T+0:02[/FONT][FONT=Calibri, sans-serif]– I already feel it coming on, there was little to no burn andmaybe a tiny bitter taste. The effects of Mxe usually build up over30mins or for me from the nasal route, but this was much quicker andreminded me more of Ketamine.

[/FONT][FONT=Calibri, sans-serif]T+1:30[/FONT][FONT=Calibri, sans-serif]– I've spent the last couple of hours in a Ketamine like daze,browsing the web but not doing much imparticular. I didn't listen tomusic but have a feel this would definitely enhance it! To mysurprise this 15mg line felt like the equivalent of a line of around80-100mg Ketamine (with no tolerance).

[/FONT][FONT=Calibri, sans-serif]T+2:00[/FONT][FONT=Calibri, sans-serif]– I'm still feeling the effects, but the have died down enough forme to feel fairly normal. One of the main reasons I do dissociativesis for the 'holing' aspect. I hate having to snort vast amounts ofanything, and I only had another 15mg of this stuff left, so afterreading varying reports (from the little info I could find!) oninjecting this stuff and also reading something about another drug inthe same family having somhe weird anti-bacterial effect (I didn'treally understand what they were writing about but it didn't soundgood), I decided to prepare a shot with what was left in mybaggie.

[/FONT][FONT=Calibri, sans-serif]T+2:05[/FONT][FONT=Calibri, sans-serif]– I wrote a little note saying what I had taken, which ROA anddosage beside my bed incase worst came to worst (but I was fairlyconfident at this dosage range, and having had experience with otherketamine/pcp analogues that i'd be safe). Then proceeded to givemyself apx. 15Mg IM injection.

[/FONT][FONT=Calibri, sans-serif]T+2:15[/FONT][FONT=Calibri, sans-serif]– I put on some tribal chanting type music and with a slide show upon youtube and laid in my bed, not expecting much more of an effectthan that which I had from snorting, and then noticed myselfteetering on the edge of a 'hole'. I don't think I full holed, but Iwas surprised at how close I got with such a littleamount!

[/FONT][FONT=Calibri, sans-serif]T+3:30ish[/FONT][FONT=Calibri, sans-serif]– I come round enough to know I'm definitely safe and reallyenjoyed the near-hole experience. It was more colourful and evenslightly euphoric compared to and MXE hole (which is what i'd beenmost used to as of late). I take a couple of Diclazepam, which Iusually find useless for sleep, but like I said I had no sleep thenight before, so drifted off fairly quickly and without much trouble.The 'hole' effects seemed to last a fair amount longer than Ketamine,which is what I was looking for when holing with MXE, but theresidual effects seem a lot shorter than MXE in terms if difficultysleeping! So it will be very interesting to further explore it onthat front!

Overall I was surprised at how much enjoyment Imanaged to get from only 30mg of this stuff, and I woke up feelingnice and refreshed the next day. A few other reports say 2-5mg dosesare quite manageable, so there's hopefully there's potential withthis for occasional anti-depressant use (which I used to use lowdoses of mxe for).

Though as it's so potent I'd see a lot ofpotential for it to get very messy in the wrong hands or wrongenvironment. (Just imagining some of the idiots who use Ketamineirresponsibly, or as a dance drug getting their hands on this makesme face-palm so hard!)[/FONT]
 
I finally tried 2-Oxo-PCE. I started with 10mg plugged (after 5 weeks off of ~20mg/4 times per week MXE usage for many months), then dosed three 5mg doses over three hours. My limited initial impression is that it's a mostly successful MXE replacement (I don't mean to imply inferiority or superiority by "mostly"). It's interesting that our collective reference frame for judging it largely reflects (I think) a break in dissociative usage patterns. That is, I imagine most people are reporting on the effects of 2-Oxo-PCE after an involuntary tolerance break from MXE (though they may have been using 3-MeO-PCP and company in the interim). We can't really imagine what sort of splash this chemical might have made had it and MXE exchanged places in the history of drug culture.
 
Start with 25-35mg. This might be underwhelming, but getting a feel for a new disso when one comes out is a must. That being said, 25mg is a pretty common, moderate dose. Just don't start any higher. It is everything that ~90mg IV MXE is. (And this is coming from a former big-time MXE enthusiast.)
 
psood0nym said:
I finally tried 2-Oxo-PCE. I started with 10mg plugged (after 5 weeks off of ~20mg/4 times per week MXE usage for many months), then dosed three 5mg doses over three hours. My limited initial impression is that it's a mostly successful MXE replacement (I don't mean to imply inferiority or superiority by "mostly"). It's interesting that our collective reference frame for judging it largely reflects (I think) a break in dissociative usage patterns. That is, I imagine most people are reporting on the effects of 2-Oxo-PCE after an involuntary tolerance break from MXE (though they may have been using 3-MeO-PCP and company in the interim). We can't really imagine what sort of splash this chemical might have made had it and MXE exchanged places in the history of drug culture.
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I completely with the last bit. The data that I found showed a break from all dissociatives for over 6 months, so no tolerance whatsoever, and the first, meager trial was sparkling, glimmering, promising. Although not with plain, blind enthusiasm. Seems like this one's a winner, barring the possible antibiotic properties.
 
This is a wondrous analogue that has me flying through fourth dimensional art galleries made of cotton candy. All is soft, warm and cozy with rolling bouts of laughter and the occasional tsunami of euphoria. I've blended it with MDMA and mushrooms and will soon be attempting a break through dose of DMT. It should come as no surprise that cannabis is an absolute perfect pairing as well. I will say I experienced a near unquenchable thirst and went through over a liter of water. My highest dose to date is roughly 20mg and felt that got me very near a hole (is it an O hole then?). Titrating up to 32mg next week. Having tried only MXP, 3meoPCP and ephenidine prior I'd have to say O-PCE trumps them without breaking a sweat. My word of caution is get a milligram scale and titrate up. Have fun and be safe.
 
My experience with O-PCE thus far has been mixed. This stuff is straight fire, like electricity. Pairing it amongst the other drugs in this class, all of them have their merits, but I'm having a hard time finding the right applications for this one as it is a beast that has yet to be tamed. It does reveal a more personal relationship to electricity. Literally it is like electricity, enhancing all sorts of electromagnetic energy senses. The come up is warm and remisniscent of MXE, a nice sheen of blanketing energy, but the tail is very long, many hours inebriatiting to the point of almost being annoying and wanting the energy to go away so that the mind can get back to its baseline current of patterns. But it does get to the heart of matter, and for that I am grateful of its message. Has anyone IV'd O-PCE yet? I want to give it a try to see it it can kill the demons left inside of me, speaking of its antibiotic properties.
 
Espiridion said:
(is it an O hole then?).
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Hahaha, maybe K-holes and M-holes should be renamed to K-corners and M-corners then ;)

Glad you enjoyed it so much. I've only tried it twice, both times at about 40mg, and I found it to be mostly dissociating but with no emotional warmth like I'd get from MXE. However I'd been taking 3-MeO-PCP almost daily at the time, so that may have interfered with it. Not sure if I'll be trying it again.
 
bjznoviskey said:
it doesn't have that feeling of flying through space and the amazing CEV dreamscapes MXE gives when I go to sleep, still amazing nonetheless.
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I was able to get these effects from it when I stepped up my dose, so maybe individual mileage varies. While still possessing a lowered dissociative tolerance from my five weeks off of MXE and the first trial noted above with O-PCE, I recently plugged 25mg to start and added two 10mg boosters over a few hours for a total of 45mg. I managed to achieve effects akin to those described in my thread Sensations of highly dynamic motion/flight with coordinated visuals?

As far as I'm concerned, O-PCE is a "full spectrum" dissociative along the lines of MXE and ketamine. If I were to place it with other dissociatives I've used between the dissociative effect poles of anesthesia/sedation and mania/heady stimulation respectively it would fall in line like so: nitrous, ketamine, O-PCE, MXE, 3-Meo-PCP, 3-ho-PCP, DXM*, Ephenidine, Methoxphenidine, Memantine*

I strongly suspect it's the anesthetic effects that are responsible for what we call "holing". That is, I believe the brain is being tricked into thinking it's sleeping and paralyzed (not embodied) and that's where we get most of the fun stuff from.

*these guys are sort of hard to situate along this dimension because of heavy SRI side effects and D2 agonism respectively, but oh well.
 
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vostochnik said:
the possible antibiotic properties.
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yes, what is the consensus on this topic ?
i think it is very important to learn whats the deal with this.

the chemical is very nice, i personally like it very much after my first few trials.
I tried it 3-4 times and would love to try it again but the possible antibiotic properties scare me. especially because i like it very much and fear that i might tend to use it 3-4 times a month... please if some one knows something for sure - let us know!

also i found a paradox with this chemical and would like to know if anyone else has found this to be true - nasal administration is stronger for me than I.V.
i tried it 3 times I.V. with ok results - there was a rush but it wasn't strong as with mxe or ketamine but more like the 3meopcp rush. So i decided to try my last amount nasally, because i decided the so-so rush was not worth the hassle and also because i was curious to see how was the trip when taken like this. And the effects were much stronger for the same amount by injection.
I split it in two lines in spaced 1-2 hours apart. It was actually so strong that i even got the robowalk which almost never happens to me with dissociatives anymore. Also the duration was a few hours longer which is a good thing too.

For people that have tried oral, sublingual and nasal - which ROA did you like the most ?
 
vortech said:
Has anyone IV'd O-PCE yet?
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Yes i have and its nice but surprisingly i got better results from nasal... maybe some metabolite is more active than the actual chemical? or maybe i fucked up the injection some how... idk. any ideas ?
 
i recently tested 15mg sublingual and had a few hours of fun with it. next weekend i will test 15mg oral and see if this ROA through the liver somehow intensifies the trip. it is possible indeed, lets wait for results.
but also i remember that mxe was oral also nearly equally active as nasal, so by far we can't say that much.
 
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