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☛ Official ☚ The Big & Dandy DOC Thread - Third opinion

thats actually a bit strange, to be feeling that sedated...
why are you using it mostly? and at what dosages? it is still as sedating at lower doses?
 
At dosages around 2 mg it is not that sedating, but not psychedelically delighting either. 4 mg is typically where I get the desired effects, but here comes the sedation I do not enjoy at all.

As to why I use it..well, to go to outside, spend a day hiking along the seashore observing the nature whilst pondering about my life and/or conversing with fellow trippers if I happen to have a company :) So gross impairment of motor skills and consciousness are not very welcome in that setting.
 
I've only had DOC 3 times... at 3mg, then 4mg, then 2mg (with 40mg 4-aco-dmt for the last one).

I feel it misses the mental stoning I like from tryptamines (there is something there, but it's a much more clear headed universe for me). I love the duration, but not the sleeplessness. It's more difficult to find time for. I feel that it will be best for me higher, 6-8mg, but my journeys there will be a while away. It's not the first thing I reach for when wanting to get stoned, connected or reflective.

I found the mixing dose the best so far, because it added some profoundness to the drug that was missing for my taste. Will post back when I get time to taste more. I have a feeling I'll be more impressed as I climb the ladder. 4mg is definitely a plus 3. And the 8 hour peak really seems divided into two separate 4 hour peaks. You really drop after 4 hours to a lower level, to a plus 2 for me with 4mg. The meat and chunks of the stone are that 8 hours though.

Disclaimer for drug quality and my measuring accuracy :)

It seems to be a very good party drug IMO. Suited to raves. I'm a fairly relaxed country type, and prefer more calm settings. The visuals on DOC are fairly amazing, but lack substance for me so far. I would say it is an interesting drug, but I wouldn't recommended it as a first psychedelic. The body rushes and temperature regulation may not suit a naive tripper. The body load could easily become a core focus of the trip.

The cost for visuals is low though, the visuals are the drugs shining glory for me. Boom yeah! and the reason to revisit.
 
Yeah DOC has great visuals. I don't get them as powerfully as I used to but they're quite beautiful and complex.

That's weird you get so sedated from it. I can get a certain sedation from it but if I take it and do some physical activity, so that I'm coming up when I'm doing that activity, it always gives me energy instead. The only complaint I have is that it causes vasoconstriction for me, so it can inhibit physical performance somewhat. I have been exploring waterfalls/rivers/swimming in cold mountain rivers on it a lot this summer and if I stay in the water too long it will make the vasoconstriction pretty intense, so that I feel my arm and leg veins pulling when I fully extend my limbs, until I warm up again.
 
DOC has never given me vasoconstriction. Sedation really remains the main issue. There is also some nausea (and only if I dose higher than 2.5 mg), but metoclopramide solves that. And while I'm on it, pretty unique to this drug, especially during the comeup, is a persistent desire to take a shit. Seriously! Several other people I tripped with commented on that as well.

I had the same sedation issues with shrooms, where medium doses made be yawning, sleepy and coach-ridden; then one member of the forum suggested that I should take a really high dose , where sedation will not be felt at all. Surprisingly it worked precisely as said, resulting in me becoming absolutely hyper and tripping my face off with a following blackout with no recollection of like last 2-3 hours. No sedation to speak of at all, only quality full-blown manic psychosis as advertised (must have been ~10 grams dry iirc).
The same strategy might be applied to DOC perhaps....but I am not too eager to test that, especially given that I am unaware of medication that could reverse the possible comatose state. Atypical antipsychotics should work in theory, but they will def. make me even more drowsy, plus they should not be combined with metoclopramide that's for sure (which would be a must on 6 mg of DOC).
 
Yeah DOC come-ups make me need to shit too, actually all stimulants do that and DOC definitely is a psychedelic amphetamine.

I get transient nausea on DOC at 3-3.5mg and above. Usually not at 3. Also if I have an empty stomach it's better, if I food in there it still affects me the same except I get nauseous. I haven't thrown up from DOC in a long time and it usually passes after the come-up period.
 
Afer, are you sure it's not the metroclopramide your taking? That's pretty sedative in its own right, even at low end doses. I do find DOC to have its own sedative properties but not the couch lock sort. Hiking was always grand with this one! One of the reasons I miss it so! I've never had much nausea on DOC thankfully.
 
I have been couch-locked on DOC before... but it involved taking a high dose (for me - 4.5mg) and then not doing anything but sitting and listening to music and browsing the Internet. If I go into it being active, I have plenty of energy. There is always a sedative aspect to it, in that I feel relaxed yet energized at the same time... never overstimulated. But I wouldn't ever think of it as sedative primarily.
 
I am pretty positive it is not metoclopramide that makes be sleepy...however this should be tested, I have almost always taken DOC along with it; perhaps they potentiate each other's side effects.
A person I once tripped with commented on how weak she felt on this one as well; she however did not consider it a drawback (this was at 2 mg). However, three other people I know did not report any sedation at all from the same batch of DOC and at the same dose that I typically take (3-4 mg). So there is plenty of interpersonal variation I guess. Oh well, sucks to be me in this regard.
 
Got my 250 mg of DOC. I put it in a little glass bowl with 2.25 g of inositol and added about 20 ml 99% isopropanol, rinsing the baggie it came in with some of it. and kept swirling the resulting slurry around as it dried. I hit it with a few seconds in the microwave a couple times to get the last bit of solvent out of it then scraped off any that was adhering to the bowl with a razorblade. I mixed and crushed it with a little plastic spoon until I was satisfied that there were no chunks and that it had a nice even consistency. It was just enough to fill a 5 gram hash oil vial. I made a little funnel type thing from a piece of aluminum foil to get it in there, putting a little spoonful in at a time and tapping it to get it to flow in.

Very pleased with how the whole operation went. No problems encountered. Now I have about 100 hits in that vial, as a lovely snow white non-hygroscopic free flowing powder, suitable for insufflation, sublingual or oral administration, or any other ROA aside from smoking, and it cost a whole lot less than acid. I can't discuss prices but let's just say it was very reasonable compared to other RCs on a per dose basis. 10-30 mg of that powder should suffice for the desired effect. Now I'll just wait for an appropriate time to test it out. Operation DOC Cut was a big success.
 
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i dont know man, liquid dosing seems safer...
its very hard to get the homogenicity (spelling?) right with powders, even when mixed like you have. which i think would have benefited more from being all in solvent at a time, not a slurry. i think it needs to be all dissolved and very very well mixed to even hope for some even distribution.

just be careful the first few times. and the times after that. if i were you id just have kept it in solution and dose the liquid, which works just the same and is easily dosable. its also comforting to know you can give it a minute's shake before use to stir everything up evenly, every time you use it.

@ afer metoclopramide can make people sleepy. i think on some formulations its even written on the paper slip with it that driving is not ok while on it. some feel these effects and others dont
 
hopefully you won't find any hotspots in your stuff because the doc I have had has always clumped into 3-4mg powder clumps or when it's been more crystal sometimes there were ones that were like 5mg or more
 
jason7 said:
Got my 250 mg of DOC. I put it in a little glass bowl with 2.25 g of inositol and added about 20 ml 99% isopropanol, rinsing the baggie it came in with some of it. and kept swirling the resulting slurry around as it dried. I hit it with a few seconds in the microwave a couple times to get the last bit of solvent out of it then scraped off any that was adhering to the bowl with a razorblade. I mixed and crushed it with a little plastic spoon until I was satisfied that there were no chunks and that it had a nice even consistency. It was just enough to fill a 5 gram hash oil vial. I made a little funnel type thing from a piece of aluminum foil to get it in there, putting a little spoonful in at a time and tapping it to get it to flow in.

Very pleased with how the whole operation went. No problems encountered. Now I have about 100 hits in that vial, as a lovely snow white non-hygroscopic free flowing powder, suitable for insufflation, sublingual or oral administration, or any other ROA aside from smoking, and it cost a whole lot less than acid. I can't discuss prices but let's just say it was very reasonable compared to other RCs on a per dose basis. 10-30 mg of that powder should suffice for the desired effect. Now I'll just wait for an appropriate time to test it out. Operation DOC Cut was a big success.
Click to expand...

Mabey next time consider dyeing your inositol to highlight any potential hotspots. I have been considering a similar method after discovering the lack of nausea when insufflating DOC compared to taking it orally.
 
Oh ROXIanne! said:
Mabey next time consider dyeing your inositol to highlight any potential hotspots. I have been considering a similar method after discovering the lack of nausea when insufflating DOC compared to taking it orally.
Click to expand...

Not really sure that would work or be foolproof, there is no telling how the dye behaves with regard to solubility. If you want to crash something out of solution all together you have to somehow do it very fast. The slower you go, the more phased it will be and your compounds are likely to come out one after another. I don't think there are ordinary methods to truly bind something to DOC or another drug you are working with, on a molecular level. And even if you did, that may very well inactivate the drug unless you can unbind it again.

I've done something like jason did like I have mentioned before, but I made a much smaller batch of the drug I was working with, so that I could actually afford considerable hotspot like variances. The bigger your batch is with respect to the dose quantity, the less you can afford hotspots / clumping etc.

Be careful, only do it if you do it in a way that allows you to afford great error margins... and otherwise just use volumetric measurement. One difference in versatility might be that insufflation with a liquid solution is usually not practical, but there are other ways for parenteral administration.

Which by the way is something I plan to explore... since rapid parenteral administration apparently compresses the long, uncomfortable, lingering come-up into a short time, so that you can get it over with a lot quicker AND cut the total duration significantly.
 
My opinion is insulfation is the best roa for doc. Oral dosing can lead to alot of people redosing before it has had time to take full effect leading to freak out etc... Anyway Solipsis That would be a intriguing compound if ever synthesized. Do you have a formula or a name for it if you ever successfully synthesized it? Also the has been talk of this drug being potentially being neurotoxic I wonder about it affecting my serotonin synapses. I have never had any problems tripping on it but that said, the euphoria and cohesiveness of my initial trails have diminished greatly. I have been taking 5 htp and was wondering if it is effecting the way my brain processes it. I have taken mama for the first time in quite a while and did it 3 or 4 times in one month. I then realized the third time I was loosing the magic tremendously. I do not take doc often as it's duration and my terrible sleeping for long periods of time post trip, make it Impractical for most situations besides festivals or whole day concerts. I dunno hoping a long break from the Mdma and other serotogenic drugs for a while will bring better results. But as of now doc idnt giving ne the little boy of magic that I loved the first time I tried it. Or is the 5 htp messing things up? Also sorry if I got off track I know this is the doc thread. Peace
 
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What compound are you talking about? I mentioned a hypothetical colored chaperone compound just for the hell of it and no I didn't make it - I wouldn't. If I did maybe I'd try synthetically binding a compound known to have a colored light emitting moiety (e.g. conjugated system like in indigo dye) to the periphery of HPBCD and then get that colored HPBCD analogue to chaperone DOC inside of the funnel-like core. Should disassociate in the body.

If you are worried about neurotoxicity definitely don't take MDMA that often. I believe neurotoxicity talk with DOC stems from its structural similarity to p-CA which is indeed toxic to serotonergic neurons. I don't believe DOC is known to do that, and it's not a terribly potent serotonin releaser or reuptake inhibitor like p-CA which is IMO a very good sign although I don't know the exact toxicological mechanism.
Don't underestimate the significance of the methoxies hanging off that ring that separates DOC from p-CA, they are an important structural difference between a lot of empathogen PEAs and psychedelic PEAs. Although I got to admit I don't know what is up with bk-2C-X compounds, and what 'crossover' drugs showing activity from different categories might have in store...
 
I've got to try insufflating DOC one of these days. Of course I don't get nausea from oral DOC, and it works great for me orally, so I've been in no hurry.
 
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