Long time lurker here to post my experiences so far with DMXE.
I've only done two tests, as I just recently got it, and promised I would slowly increment my way up.
An hour after a 1 mg allergy test of the tan sand, the first real test was 10 mg insufflated. Come on was sharp and rough around the edges. Was pretty surprised how much just 10mg actually affected me... it was greatly potentiated with weed as well. I had a scary moment where my heart was going a bit fast, and I was momentarily paranoid, probably because of the big vape hit I took though. I accidentally vaped too much I think. Very strong MXE vibes, but also different. The trip was rather short but I still felt wired after the peak. I had a sharp headache and felt very malaise the next day, but it could be because I quit a few-months-long of drinking that same day. Also I did it a bit late at night and had trouble falling asleep. The afterglow lasted for days, like DXM but much cleaner. Even on such a small dose. I did not have nearly as long a glow on much higher doses of MXE. The DMXE glow has very powerful anti-depressant effects though. I was more smiley pretty much the whole week.
The next test was done 5 days later. This time 20 mg sublingual. The come on and over-all experience was much more well rounded and enjoyable. Took longer to come on, but lasted longer and wasn't so rough around the edges. I will probably use this ROA from now on, maybe with a small insufflated titration dose at the end of the onset. This time I did it in the middle of the day. I went for a walk during the onset on what was probably the last nice day of the year and really enjoyed it. Upon arriving home, when I was just at my computer or talking to my wife or doing normal things, the effects weren't too noticeable, but when I lay down and focused on myself in the dark listening to music, it took me on a mental journey. No real visuals, but cool thoughts of understanding the music and letting it take my mind places. Very comforting and relaxing. I was able to stretch a stretch like never before and felt totally at peace. When I got up and went upstairs though, the quick change in elevation and exertion made me have another heart thumping scary moment, but it quickly subsided. Was sober enough to be normal when the kids came home, and when I played with them I felt closer to them than usual. Real empathogenic feelings.
I barely had any comedown and no hangover/headache the next day after sublingual intake. The afterglow again lasts for days. Very clean and antidepressant. I did get a bit light-headed sometimes the next day, but only after I smoked weed. Weed is still potentiated during the glow, so it leads to me smoking less. Also I feel I need less caffeine. And I still haven't touched any alcohol since the first day. I think this substance just straight up made me quit drinking. I had quit the first day because I didn't want it to effect the experience, as mixing alco and dissos is not really a good idea. But now I don't even feel like beer or vodka anymore.
I got this substance because I was tired of spending $300 apiece for legal ketamine treatments at a clinic. I would say this chemical is doing exactly what I had hoped.
I am excited to try higher doses, as I have barely scratched the surface, but I do worry about how strong the afterglow will be. It feels pretty strong already just off of these low doses, so I am hoping that it isn't 100% linearly related to the dose, because if so a 100 mg dose would probably make my completely dysfunctional the next few days lol.
Anyways, I would say this is a great chem so far. I have high hopes. For me, the desire to redose is low due to the strong afterglow. It helps make it easy to follow my plan to wait at least 5 days or more between doses. This is a bonus, because when I had MXE I remembered all I wanted to do was redose redose redose. I feel I have much more control with this chem, and the positive side effects last longer. I was a bit worried after feeling such a hangover after insufflation, but the sublingual intake seems to completely avoid this. I had a bit of trouble with urination the first time, but the second time I had a big glass of apple-juice at breakfast before my dose which seemed to fix the issue.
The real beauty is that it doesn't completely ruin my appetite. When the trip is over and I'm hungry, I can eat no problem. In the mornings, the afterglow does make me not want to eat immediately like I usually do, but I still do eat. The glow also makes me horny as fuck btw. Can't explain it.
I will make another post as I continue my research. My next attempt will be 30 mg sublingual.