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Dissociatives The Big & Dandy DMXE (3-me-2′-oxo-PCE, deoxymethoxetamine) Thread

Sì, è quello che mi è stato detto, anche se poiché non l'ho acquistato direttamente dal laboratorio non posso esserne sicuro. Il venditore è di lunga data anche se solo di recente ha iniziato a specializzarsi nell'arbitraggio rettiliano. Tuttavia, ho già acquistato altri prodotti di laboratorio da lui, incluso il precedente lotto di sabbia DMXE gialla.

La mia prima preoccupazione è stata che si è trattato di un errore e mi è stato inviato 3-ho-pcp, dal momento che sembra molto simile a un lotto grigio che ho avuto in passato (per quanto mi ricordo, sono passati anni ). Ma 20 mg di 3-ho-pcp sarebbero del tutto troppi, mentre questo era relativamente leggero e gestibile, anche se lapidante.

Ho fatto delle indagini e mi sono imbattuto in alcuni commenti reddit che spiegavano che "batch n. 2" è il lotto di sabbia gialla/marrone/marrone chiaro, il che implica che esiste (o esisteva) anche un lotto n. 1, anche se non riesco a trovarne una descrizione. Ho anche trovato alcuni commenti casuali su un lotto grigio ma niente di più. Contatterò il mio fornitore per confermare, ma al momento credo che questo sia DMXE di quel laboratorio specifico, solo un lotto diverso.

Modifica: il fornitore lo ha confermato come DMXE dal noto fornitore. Mi ha inviato una foto del suo stock per confermare che ciò che ho ricevuto è lo stesso, ed era. Quindi a quanto pare c'è un nuovo lotto grigio?
The DMXE I ordered the last few months had a different texture and was more grainy and yellow, while the last batch I received a few days ago is more sandy and gray, and the effects, even if almost identical, seem slightly different to me, ,, perhaps more relaxing. But I still have to try a strong dose of this batch to be sure, as I have been snorting a lot of ketamine these days, and yesterday I mixed them.
 
The DMXE I ordered the last few months had a different texture and was more grainy and yellow, while the last batch I received a few days ago is more sandy and gray, and the effects, even if almost identical, seem slightly different to me, ,, perhaps more relaxing. But I still have to try a strong dose of this batch to be sure, as I have been snorting a lot of ketamine these days, and yesterday I mixed them.

Sounds like we have the same batch then. And very interesting, that's exactly how I feel about it -- the effects seem very similar but ever so slightly different; I'd agree with your description of "more relaxing." I also thought it was more mellow and/or more chill etc. Not really sure how to put it.

I also actually thought it was a tolerance issue for me and wrote it off as just that, so it's very interesting that you had similar thoughts. Curious if other people feel similarly after trying it.
 
Anyone here with some ket tolerance who can give advice about dosage?
I can still hole on 100-150mg IM if ive had a few weeks of.
I usually do around 1-5g ket most months but have had longer breaks in periods but also major binges where ive done well over 10g in a week.
 
Finally got around to trying this one, now that I was shipped the proper chemical. I try not to use dissociatives on work nights but I did it last night because I've been in a bit of a depression. The other night I used 2f-dck which I found to work great to break me out of my depression at the moment. Tonight, so far I have done 75mg snorted over the course of an hour. At this dose its fairly mild for me (I have a bit of a tolerance). There is a little bit of euphoria in its effect, but still I'm finding myself in a depressed mindset. So DMXE seems to be not as effective for treating acute depression for me as 2f-dck is.

I can see where the comparisons to MXE are coming from. To me it feels like a mix of MXE and MXPr, but much closer to MXPr in effect than MXE.

Edit:
Woke up the next day feeling much less depressed than I have the last few days. So maybe it does have some anti-depressant effect, the results just weren't as immediate when compared to Ketamine, 2f-dck, 3fl-pcp,3cl-pcp,etc.
 
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Finally got around to trying this one, now that I was shipped the proper chemical. I try not to use dissociatives on work nights but I did it last night because I've been in a bit of a depression. The other night I used 2f-dck which I found to work great to break me out of my depression at the moment. Tonight, so far I have done 75mg snorted over the course of an hour. At this dose its fairly mild for me (I have a bit of a tolerance). There is a little bit of euphoria in its effect, but still I'm finding myself in a depressed mindset. So DMXE seems to be not as effective for treating acute depression for me as 2f-dck is.

I can see where the comparisons to MXE are coming from. To me it feels like a mix of MXE and MXPr, but much closer to MXPr in effect than MXE.

Edit:
Woke up the next day feeling much less depressed than I have the last few days. So maybe it does have some anti-depressant effect, the results just weren't as immediate when compared to Ketamine, 2f-dck, 3fl-pcp,3cl-pcp,etc.
For me mxe shined mostly in the day after.
Sure the hole and acute effects were awesome.
But the real magic was in how great i felt a day after dosing.
 
Anyone here with some ket tolerance who can give advice about dosage?
I can still hole on 100-150mg IM if ive had a few weeks of.
I usually do around 1-5g ket most months but have had longer breaks in periods but also major binges where ive done well over 10g in a week.
Picked up 0,5g today, did a small allergy test by sticking my finger in the bag.
Actually going to try some IM shots to compare the potency and duration of Ket.
Starting very low of course.
 
Picked up 0,5g today, did a small allergy test by sticking my finger in the bag.
Actually going to try some IM shots to compare the potency and duration of Ket.
Starting very low of course.
I'm a little disappointed in the potency myself. It took me about 150mg of DMXE snorted to get to a good level. 250mg snorted over the course of a couple of hours was pretty friggin' awesome. I really like the effects of this one. I wish it was cheaper though. It sucks paying $30 for a decent trip. For that price I could be doing mescaline lol. It's awesome stuff though and I definitely plan on getting more when I can.

I have been using dissociatives for most of my adult life, so I have a pretty decent tolerance. I'm not suggesting that anyone starts at the doses I took. Always start low.

When I first took it I think I snorted 25mg and got barely threshold effects and kept doing 25mg bumps until I got to a good level. I started getting tangible effects around 60mg. Started to get wonky once I went over 120mg.

Who here has tried both oral and insufflated? Which did you prefer? I've always been one to snort my dissos but I've destroyed my nose over the years and have been trying to dose orally more often and I'm finding that oral usually provides a more fleshed out experience and the dosages are about the same orally as snorted with most arylcyclohexylamines that I've done. I'm just afraid of wasting such an expensive chemical by taking it orally just to find that its ineffective.
 
It took me about 150mg of DMXE snorted to get to a good level. 250mg snorted over the course of a couple of hours was pretty friggin' awesome. I really like the effects of this one. I wish it was cheaper though. It sucks paying $30 for a decent trip. For that price I could be doing mescaline lol. It's awesome stuff though and I definitely plan on getting more when I can.
Do you have high disso tolerance or did you get a really bad batch? I personally find that I can get decent effects from 20-30mg and 40-50mg usually gets me where I want to be.
 
Do you have high disso tolerance or did you get a really bad batch? I personally find that I can get decent effects from 20-30mg and 40-50mg usually gets me where I want to be.

As far as I know the batch that I got is decent. It's from a reputable lab who usually put out quality material. This is the only batch I've gotten so far, not counting the time that I ordered 2g and got 5-MAPB instead.

I have a pretty decent dissociative tolerance. Not outrageous, but I require more material than a dissociative naive user. Used DXM pretty heavily in my teen years and have used dissociatives for a good amount of my adult life. Only time I haven't used dissociatives is when I was broke, using stims and/or opioids heavily, or during on of the short periods where I got completely sober. I've been using dissociatives regularly for 2 or 3 years this time around. The frequency of my use fluctuates, but I typically use a dissociative 2 or 3 days a week. Sometimes I use them almost every day when I have a case of the "eff it's". A month or two back I went through a period where I was using FXE every day and even though I've somewhat slowed my use since then, I feel like my tolerance hasnt gone down much from the FXE. I was using probably around 1000mg of FXE almost daily there for a bit.

That said, I've only done DMXE the twice and can't really compare the experience intensity to other stuff that I'm more experienced with. I do require around 10mg of 3-HO-PCP to get me to where I imagine 5-6mg would get someone without my tolerance. 250+mg of DMXE was great and never felt too intense or anything. The effects were getting pretty strong but never to the point where I found the experience difficult. At that dose I found myself still wanting more and probably would have taken it if I didn't work the next day. I am definitely due for an extended tolerance break.

What RoA do you typically use for DMXE?
 
I get pretty wired up on 10

Full focus and bliss on 30-40

Edging hole for hours on 60-80

Might try oral next time. The nose is increasingly displeased even with moderate infrequent use. Last time i think it exacerbated a very minor infection, and my nose was running to the point of skin irritation from all the wiping. If oral works, it be a better option. I will report back when i get around to it.
 
Yes, that is what I was told, though since I did not purchase it directly from the lab I cannot actually be sure. The vendor is long-standing though only recently started specializing in reptilian arbitrage. I've bought other lab-sourced goods from him before though, including the prior yellow DMXE sand batch.

My first concern was that it was a mix-up and I was sent 3-ho-pcp, since it looks most similar to a grey batch of that I have had in the past (to the best of my recollection -- it's been years). But 20mg of 3-ho-pcp would be entirely too much, while this was relatively light and manageable, albeit stoning.

I did some sleuthing and stumbled upon some reddit comments explaining that "batch #2" is the yellow/brown/tan sand batch, implying a batch #1 also exists (or existed), though I cannot find a description of it. I also found some random comments about a grey batch but nothing more than that. I'll reach out to my vendor to confirm, but as of right now I do believe this is DMXE from that specific lab, just a different batch.

Edit: vendor confirmed it as DMXE from the well known supplier. He sent me a picture of his stock to confirm what I received is the same, which it was. So apparently there is a new grey batch?
The sandish batch was fire. Recent grey batches smelled like gasoline when insufflated and definitely weaker than the sandish one. Must be contaminated right? I hoped it was only temporary, but last batch had the same shit smell. always from the same reputable source. Do you have same experiences with the 'new' batch?
 
Who here has tried both oral and insufflated? Which did you prefer? I've always been one to snort my dissos but I've destroyed my nose over the years and have been trying to dose orally more often and I'm finding that oral usually provides a more fleshed out experience and the dosages are about the same orally as snorted with most arylcyclohexylamines that I've done. I'm just afraid of wasting such an expensive chemical by taking it orally just to find that its ineffective.

I feel the same way... for me, most ACHs are better orally, and about the same potency, or even sometimes more potent, than nasal. I always much preferred MXE orally, nasally it felt like a shadow of the fantastic effects I got orally. More stimulating and less fleshed out, just like you said. Also shorter in duration. I find the same is true with DMXE. For whatever reason, ketamine is different. But 2f-DCK, weirdly, I find far more potent orally, like twice as potent, easily.
 
I feel the same way... for me, most ACHs are better orally, and about the same potency, or even sometimes more potent, than nasal. I always much preferred MXE orally, nasally it felt like a shadow of the fantastic effects I got orally. More stimulating and less fleshed out, just like you said. Also shorter in duration. I find the same is true with DMXE. For whatever reason, ketamine is different. But 2f-DCK, weirdly, I find far more potent orally, like twice as potent, easily.

Good to know! I'll try DMXE orally next time. only have 200mg left and have only tried it snorted. I sure hope that its still on the market after Christmas. Wont be able to afford anymore until then. I really enjoyed the effects and would like to stock up. Super warm and cozy and great for watching stuff. I usually play video games when I use dissociatives but for some reason on DMXE playing video games seemed like too much work and didn't sound interesting to me. Like all I wanted to do was lay there and enjoy feeling like a marshmallow. It's the 3rd drug to make me feel like a marshmallow. The first is high dose 3-HO-PCP (was kinda unsettling the first time i turned into a marshmallow out of nowhere, now I enjoy it). The 2nd was MXPr but I only got turned into a marshmallow my first 2 or 3 times trying it. After that the effects became kind of cold, clinical and robotic. And the 3rd to turn me into a Marshmallow is DMXE. We'll see if that effect goes beyond the first few experiences like 3-HO-PCP or if they disappear out of nowhere like MXPr.

I have the same reaction though when it comes to oral vs nasal. I just tend to go with nasal for the quick onset but have been trying to be better about practicing patience and consuming them orally. Like you said, Ketamine is the only ACH that I've gotten significantly increased potency from snorting. I feel like like 3-MeO-PCP was more potent nasally as well but not by too much. I just snorted it all the time because I didn't want to wait 2 hours to peak, although oral did produce a nicer body high and more psychedelic headspace. 2f-DCK is the same for me as well, it's at least twice as potent orally. I wish I had figured it out sooner. I went through like half a gram before deciding to try it orally and was surprised by how much stronger it was orally. It's a shame that it requires such high doses because I found 2f-dck to be extremely enjoyable.

I wonder what it is about Ketamine that makes the bioavailability so low when dosed orally compared to other close analogues?
 
Beautiful compound, i miss being able to obtain this chem it's truly spectacular i love the hole the euphoria everything great chem all around might be considered cold or clinical like ketamine but I love dark substances that show you the truth of this world. Not to say i like cold substances but I think this chemical can show you a lot in terms of what this life offers. Someone said it best in this tread that this compound is good for "death realization" i think this is very accurate and this Substance should be handled carefully.
 
I do all my dissos sublingual. To date I havent found any caustic one.

Plugged use to work wonders on dissos too. Whatever but the nose
 
The sandish batch was fire. Recent grey batches smelled like gasoline when insufflated and definitely weaker than the sandish one. Must be contaminated right? I hoped it was only temporary, but last batch had the same shit smell. always from the same reputable source. Do you have same experiences with the 'new' batch?

I agree, the new grey batch is definitely less potent than the previous yellow sand batch. I haven't noticed an increase in hangover or side-effects or similar, but I've been doing much smaller doses recently (due to circumstances unrelated to this batch). I am starting to feel that there is a difference in effect though, this batch seems less...thought-generating? and more stoning? than the previous batch. With that said, more likely than not that is just an artifact of set/setting, tolerance, or something along those lines. We'll see how future experiences go.

Anyone else try this new batch and have opinions on it vs the old batch?
 
Long time lurker here to post my experiences so far with DMXE.

I've only done two tests, as I just recently got it, and promised I would slowly increment my way up.

An hour after a 1 mg allergy test of the tan sand, the first real test was 10 mg insufflated. Come on was sharp and rough around the edges. Was pretty surprised how much just 10mg actually affected me... it was greatly potentiated with weed as well. I had a scary moment where my heart was going a bit fast, and I was momentarily paranoid, probably because of the big vape hit I took though. I accidentally vaped too much I think. Very strong MXE vibes, but also different. The trip was rather short but I still felt wired after the peak. I had a sharp headache and felt very malaise the next day, but it could be because I quit a few-months-long of drinking that same day. Also I did it a bit late at night and had trouble falling asleep. The afterglow lasted for days, like DXM but much cleaner. Even on such a small dose. I did not have nearly as long a glow on much higher doses of MXE. The DMXE glow has very powerful anti-depressant effects though. I was more smiley pretty much the whole week.

The next test was done 5 days later. This time 20 mg sublingual. The come on and over-all experience was much more well rounded and enjoyable. Took longer to come on, but lasted longer and wasn't so rough around the edges. I will probably use this ROA from now on, maybe with a small insufflated titration dose at the end of the onset. This time I did it in the middle of the day. I went for a walk during the onset on what was probably the last nice day of the year and really enjoyed it. Upon arriving home, when I was just at my computer or talking to my wife or doing normal things, the effects weren't too noticeable, but when I lay down and focused on myself in the dark listening to music, it took me on a mental journey. No real visuals, but cool thoughts of understanding the music and letting it take my mind places. Very comforting and relaxing. I was able to stretch a stretch like never before and felt totally at peace. When I got up and went upstairs though, the quick change in elevation and exertion made me have another heart thumping scary moment, but it quickly subsided. Was sober enough to be normal when the kids came home, and when I played with them I felt closer to them than usual. Real empathogenic feelings.

I barely had any comedown and no hangover/headache the next day after sublingual intake. The afterglow again lasts for days. Very clean and antidepressant. I did get a bit light-headed sometimes the next day, but only after I smoked weed. Weed is still potentiated during the glow, so it leads to me smoking less. Also I feel I need less caffeine. And I still haven't touched any alcohol since the first day. I think this substance just straight up made me quit drinking. I had quit the first day because I didn't want it to effect the experience, as mixing alco and dissos is not really a good idea. But now I don't even feel like beer or vodka anymore.

I got this substance because I was tired of spending $300 apiece for legal ketamine treatments at a clinic. I would say this chemical is doing exactly what I had hoped.

I am excited to try higher doses, as I have barely scratched the surface, but I do worry about how strong the afterglow will be. It feels pretty strong already just off of these low doses, so I am hoping that it isn't 100% linearly related to the dose, because if so a 100 mg dose would probably make my completely dysfunctional the next few days lol.

Anyways, I would say this is a great chem so far. I have high hopes. For me, the desire to redose is low due to the strong afterglow. It helps make it easy to follow my plan to wait at least 5 days or more between doses. This is a bonus, because when I had MXE I remembered all I wanted to do was redose redose redose. I feel I have much more control with this chem, and the positive side effects last longer. I was a bit worried after feeling such a hangover after insufflation, but the sublingual intake seems to completely avoid this. I had a bit of trouble with urination the first time, but the second time I had a big glass of apple-juice at breakfast before my dose which seemed to fix the issue.

The real beauty is that it doesn't completely ruin my appetite. When the trip is over and I'm hungry, I can eat no problem. In the mornings, the afterglow does make me not want to eat immediately like I usually do, but I still do eat. The glow also makes me horny as fuck btw. Can't explain it.

I will make another post as I continue my research. My next attempt will be 30 mg sublingual.
 
My next dose was 27 mg sublingual followed by two 8 mg insufflations at T+1 and T+2.

Enjoyed a really good body buzz with that signature disso candy-cane feeling in the face. Tried to play some league of legends... lost horribly but had a great time. I had more of a hands on experience, not really able to drift away to music like last time but instead turned my room into a dance party with the lights off. Couldn't stop dancing. Was pretty social with friends on discord and the wife at home. Zero hangover, zero headache, but still feeling good the next day. Really enjoying this chem, but that experience did feel a BIT shallow. Was hoping for more introspection, but still had a good time overall.

I wonder if 5 days isn't enough time to rid myself of tolerance. Maybe I will wait longer for the next experience. Gonna start right off the bat with 50 mg sublingual next time, with perhaps a single 15 mg titration at T+1.

Edit: One thing I wanted to mention is that, although the desire to redose is very low during the afterglow, the desire to redose is still pretty high during the initial comedown once the lovely candy-cane disso vibe initially wears. However, if you can control yourself during that part, then the next day you don't really feel like redosing. At least in my experience.
 
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Picked up 0,5g today, did a small allergy test by sticking my finger in the bag.
Actually going to try some IM shots to compare the potency and duration of Ket.
Starting very low of course.
So that didnt end well....

I almost always do IM shots when using ketamine.
So i used this roa with dmxe aswell..

I started with just 10mg, it was actually quite nice at this dose.
I remember waiting for some time then doing a refill.
After that my first memory is my gf coming home with me totally messed up and had torn a bunch of stuff down etc.

I tossed the rest the day after, i cant use dissiociatives anymore except nitrous.
My perma tolerance has just ruined this class of drugs.
I either barely feel anything or i get super retarded and black out/random redose frenzy etc.

Honestly i feel quite done with them after this last mishap.
But ive had long breaks before and somehow i end up in the hole again sooner or later.

It was way easier when there werent cheap high grade ket available lol.

Well at least i can say ive tried this drug, if you dont have heavy tolerance it is probably the best mxe analogue so far.
It felt quite nice before i took to much.
 
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