The Big & Dandy Combo Thread

[Ximot]

2C-I + 5-MEO-DMT
med/high dose 2C-I plus a sub-breakthrough hit during the peak. Just one is all it takes; no need to go crazy. I find 2C-E to be an incredibly intellectual drug in many ways. Its clarity is unmatched. Throwing a bit of 5-MEO-DMT into the mix accentuates this, for me personally, to an unspeakable degree.

pretty much I feel like I completely transcend human logic and simply know all when I dip into this stuff. It isn't overpowering and disarming like a whopping hit of 5-MEO-DMT, it's subtle and natural and integrates perfectly with your waking consciousness. Highly recommended combo for anyone who genuinely loves to think.

for clarity's sake: 2CI or 2CE?

 

[spun420 v. 2.0]

4-aco-mipt + mdma powder to begegin followed by whippets, then late in the evening some Ketamine then a few good benzos to tdrift off to sleep, or hell maybe another rail of mollly

 

[phillo]

dpt (25mg bumped) + mdma (1 pill booty bumped) - pleasurable/sensual

2c-e (20ishmg) + 5-meo-mipt (5mg) - intense and and physically euphoric, blissful physical sensations. a small 'bump' of 5-meo-mipt (3-5mg) after the peak of the 2c-e is intensely visual and fun.

1 blootter acid + 1 bottle tussin\8 oz xtra strength/dxm - one of the top 5 most insane experiences of my life - changed me permanently. born of this trip was a character, like an snl character. my friend and i, who'd taken the same combo hallucinated a town. we called the town neonville (the room was lit only w/blacklight, there was lots of neon) and became its characters. it was a strange kind of ego loss, becoming many instead of nothing. don't know if i'd try this again.

2c-t-2 (6 mg) + 5-meo-mipt (8 mg) + 2c-i (4 mg) - this was intense in terms of sensory changes. it was very visual, in a generic way. physically it was too pleasurable; like, pleasure overload. all of these chemicals are physically enjoyable in subtle (at these doses) but different ways. all together, weird and wrong. the most fun was had playimg grand theft auto; my driving was great, and the game was vivid and realistic. off topic: i want to try playing video games on certain substances more often: true fun.

 

[Ximot]

One LSD blotter followed by M1 after 6 hours... (making music) ... (go out, event, party)... add alcohol... add more LSD as well as some MDMA after about 10 hours... add more alcohol (just beer, really) ... don't forget to smoke cannabis throughout... oh yeah, then, when you know the drugs are wearing off and you're back home staring at the Hubble space telescope videos in order to finally dig the Universe with a friend, about 16 hours after you first took the LSD, take another 130mg MDMA and add 20mg 4-AcO-MIPT for good measure... if in doubt, add 20mg K.

Only downside this had was a sheer inability to urinate for over 2 hours about 4 hours after the last drug cocktail was taken. This was a bit freaky as I got a bit paranoid and thought I had a kidney stone stuck in my bladder. Alas, as I found out later, this was not so. Still, a good reminder not to go overboard entirely and respect one's organism.

The most amazing thing is I didn't get any comedown from this experience. Took place last weekend, and I seem to have made a decent recovery. No depression noted. One reason for this may be that I used the drugs wisely in the sense that I didn't go for hedonistic overkill but actually had a very integrative, holistic experience in which I shied away from nothing in order to help a friend out of a rut through asking questions, listening and, occasionally, talking.

It's amazing how little of a comedown I have this week, even though I took more MDMA than I can normally get away with. Maybe it's because I hadn't used MDMA for several months beforehand. I remember getting nasty midweek mood slumps back then. Even days later I still actually feel like I have liberated myself from the fangs of my pleasure/laziness demons. We'll see how long this lasts :D

Even my friend, who had a spiritually difficult time during the last part of the experience, is doing okay this week.

 

[nbsp]

for clarity's sake: 2CI or 2CE?

wow, can't believe I actually wrote that.

I mean 2C-E. I edited my post.

 

[Xorkoth]

Re: Ximot -

I've noticed that taking a serotonergic psychedelic, especially a tryptamine, after MDMA or any other draining substance like methylone really practically eliminates the comedown/aftereffects. In fact, it's never failed me. Good psychedelics have zero comedown or negative aftereffects for me, and if I'm feeling crappy (from drugs anyway) and I take one, I'll be sure to feel fine afterwards. The once time I really went overboard on MDMA, I took a dose of DOC and after a wonderful, glowing experience, I never felt any negative aftereffects or comedown from the excess and many redosings over two days of MDMA.

 

[Ximot]

/\ what I forgot to mention with my combo above is that I'd also had 4.5mg hydergine along with my initial acid hit. though i do not do acid regularly enough to be able to say if it had any effect. May have made it a tad stronger perhaps but it's hard to say.

what you say about "good psychedelics" makes sense to me, it sounds so true. Bust how do you define "good" ? Those which have "zero comedown"? This would make your statement a a bit tautological in my book.

For me a large part of feeling well afterwards is about integrating my experience before I go to sleep after it has worn off. But there are subtle lingering physical manifestations with some of them even if the trip was wholesome. For me, these have included 5-Meo-MIPT, 5-MeO-DIPT, AMT, AET, MDMA (obviously! a major one) 2CP, 2CT2. To a lesser extent 2CT7. I don't get that at all from most of the 4-substituted series... especially 4-Aco-MIPT, 4-AcO-DIPT and 4-AcO-DMT. They actually make me feel refreshed afterwards. AMT, while seemingly refreshing at first, I suspect of depleting my energy levels quite a lot after the 2-day afterglow has worn off.

 

[J_B_Wild]

M1 175 mg followed around 2.5 hours later by 20mg 2c-b:

I felt very heavy and had less energy then I would have liked. The euphoria was not really there, but some pretty decent introspection. All in all, I believe the 2c-b helped tremendously with the comedown, but probably was to high of a dose when combined in that way.

2c-b 8mg, moderate weed, moderate/small amount of alcohol:

WOW!, now this was a blast. I am assuming that half the fun was not expecting much and just having so much positive energy and wanting to dance all night made it a nice surprise.

30grams dried peruvian after having taken a normal dose of piracetam:

Now this was a mistake. I typically take piracetam or aniracetam in the mornings before I work out and simply didn't think about the fact that I still had it in my system on my first try of mescaline. It was overwealming, but nevertheless remains my most cherished ride.

One question that I have for all of you experienced trippers is with 2c-b and mdma. From what I have read, it seems like the suggestion is 2c-b at the tail end of the mdma trip. I have however read some blurbs that suggest if you take the 2c-b with the mdma, you will greatly enhance the mdma trip. If any of you can go into more detail on this combo, what the effects are if done at the same time, versus doing the 2c-b as the mdma is wearing off, as well as suggested doses for 2c-b assuming that the mdma amount was somewhere between 150-200mg, done in one, perhaps two doses max. Also, if you can enlighten me on the length of time each combo lasts for, I would very much appreciate it.

Thanks in advance

 

[Jabberwocky]

8mg ergoloid mesylate +1.25g piracetam +250mg DMAE +copious marijuana.

very intense visuals!

 

[Swerlz]

^tell me more..

 

[illusion25]

ketamine + any tryptamine...my favorite combos

 

[Jabberwocky]

This was last night...very rough trip report...I think the visual effects were in large part because of the combo but also because of the amount of DMT and 2Cs I've been doing lately.

T+0:00: ingest 8mg pure ergoloid mesylate, 1.25g piracetam, 250mg DMAE

T+0:30: Eyes dilated very large from erg. mesylate and thoughts/memories racing from the rest. Rapidly vaporize about 4 full hits of marijuana from a lightbulb.

T+0:45: Stoned off my lovin' ass! The body buzz is GREATLY increased from the nootropics, my whole body is vibrating and my head/brain is tingling (like a phen trip). I definitely feel like I am tripping.

T+1:30: Go into the bathroom and the (normally white) sink is turning blue and orange and is swaying back and forth from its 'base.' My eyes are dilated as large as I have ever seen them. CEVs are quite intense. Very phenethylamine, I think.

T+2:00: Lay down on the carpet just breathing and squirming my body (a la 2CD trip) and enjoy the next 2 hours (and eventually fall asleep there).

 

[Xorkoth]

Curious. I've only taken hydergine above 4.5mg once, and that was at 9mg. I definitely was an experience but far below visual. More like I was so aware I could not stop my brain, but I wouldn't call it a trip. You seem to react strongly to ergoloid mesylates.

Either that or your pure product is superior to manufactured Hydergine...

Hmm...

 

[Jabberwocky]

yeah, I would be curious to see whether or not hydergine tabs dilate my eyes like this batch does. Yes, the brain races on the chemical, very fast and very emotional memories rise up one after another.

 

[Doctor__Anonymous]

anyone mixed a low dose of DXM with HBWR seeds before?

 

[cornollio]

^ i hope not.

 

[georgiapoppy]

Nitrous is always extremely intense. However, I try not to do it anymore since I always end up chasing the high and I can sit there doing them for hours.

Using some type of 'Rush' (poppers, butyl nitrite, etc) is also extremely intense while tripping. Although short-lived, within seconds of a hit, the trip is intensifed beyond belief and the euphoria is incredible. It's great combined with nitrous as well. Take a hit of Rush, and then immediately follow it with one or two bulbs of nitrous.

Quality lab-grade ether is also a mind bender while tripping. Nothing like a good ether binge. I'm starting to sound like a huffer, so I'll stop with the inhalent talk now. %) I've also used several medical-grade (inahaled) anesthetics in the past with incredible effect while on a psychedelic.

I don't use inhalents often, but a little bit of any of the above is a great combination with almost any psychedelic. I don't think the ones above are really that damaging to one's health either if used in moderation.

Anyway as far as psychedelic combinations go, I have used the following to great effect:

1) 4-HO-MiPT/4-AcO-MiPT - Only done this combo once. I had finished empyting out a baggie of each chem while weighing out a few doses of each for future use. Prior to discarding the baggies, I tore them open and licked each of them clean. I wasn't planning on tripping that night and was just expecting mild mood enhancement if anything. I got much more than I expected. During the peak, a few hits of nitrous brought me to a +4. I plan on trying this combo again at some point in the future. These two chems synergize very well with each other, so I will probably start low and work my way up.

2) DPT/4-HO-MiPT - Have only done this combo once too, but it was simply indecribable. I also plan on repeating this at some point in the future.

3) Peruvian Torch in combination with several of the 2C's - Dried outer skin 'chips' of T. peruvianus that were extremely potent were ground up and loaded into capsules. Low doses of this used to 'accent' 2ct2, 2cc and 2cd were incredible. What would normally be a threshold dose of the cactus by itself were very synergistic and did a great job with the three 2c's mentioned. I am interested in repeating it in the future as well as trying it with 2ce, 2ci, 2ct4 and 2cp at some point. %) I also think 2ct21 would be very nice to combine with mescaline.

 

[blue)dolphin]

4-xxx-Tryptamine combinations?

Hey all,

I'm curious if anybody has tried combining such chemicals like 4acoDMT, 4hoMiPT, 4hoDiPT , or other related tryptamines.

I'm thinking that using 4acoDMT as a "base", maybe 12mg or so, due to its remarkably smooth and beautiful effects, and then maybe adding 4mg or so 4hoMiPT might result in something amazing.

Is it true that when combining amounts of different tryptamines they somewhat potentiate each other?

I'd love to hear thoughts and especially experiences. Thanks

 

[mezcal]

In my experience, combining PEA's with PEA's and TA's with TA's that have similar effects doesn't add anything significant to the experience.

In many respects, the drugs can be considered competitive partial agonists. Adding one to another alters the overall profile of the alteration in 5ht reception much, much less than when each substance is added independently.

The profile, however, is remarkably different depending on dosage.

If you're dealing with lower-range/threshold doses of 2 compounds, you can reach a state of additive stimulation from both drugs simultaneously. Borderline-sub-threshold doses of two different drugs definitely produce something noticeable. Whether that effect could be distinguished from an equivalent dosage of either compound depends on how similar the two are. For example: 5-meo-dipt and 4-ho-dmt would no doubt be a unique combination. 4-aco-dmt and 4-ho-mipt? I'm not sure. The problem here with subjective judgement is that it has a heavy influence of confounds originated from expectations, set and setting.

As doses increase to "intense" levels, adding more of a less competitive agonist will likely have a diminishing effect as the more competitive binding compound will take up most active sites. Imagine, for example, 8mg DOB and 20mg 2C-B.

That's my take

Personally the only combinations that I've really enjoyed are:

* MDMA, mushrooms on comedown with small doses of hashish
* Harmaline concurrent with DMT
* MDMA, 2C-B both less than half-doses

MDMA and methylone for me was a waste of MDMA as it seemed the methylone was a stronger competitor for SERT sites but had less effect.

Dissociatives, on the other hand, seem to be more interesting as they are combined, regardless of what is combined. Why? Gornoplat.

 

[egor]

20mg of 4-ho-mipt with 2g of cubensis was an amazingly fun.
3g of psilocybin with approx 10 mg of 4- ho-dipt was also a good time.