That's my favourite of the 'mescaline analogues'. I'm also somewhat interested in isolated Amanita alkaloids.
30mg is a lot, no a shitload. Do you have a tolerance to psychedelics?
Dissociatives The Big & Dandy Amanita Mushrooms Thread
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30mg is a lot, no a shitload. Do you have a tolerance to psychedelics?
Not really. I just like my doses strong.
Oh, and I find 2C-E to be really gentle and relaxing. First time I took it (no tolerance) I took 20mg and I was underwhelmed. 30mgs seems to be my ideal dose - the visuals are great and the euphoria is intense but the mindfuck isn't so strong that I can't function.
One time I took over 50mgs and I had a great trip. I went totally loopy and spent most of that trip crashed out on the couch listening to chopped and screwed hip hop and drooling like a cretin. I couldn't even tell whether my eyes were open or closed but it was a fun experience.
Has anyone manage to get anything worthwhile out of the YELLOW amanitas (amanita formosa, americamuscaria)? The ones from the east coast us? Ive done plenty of research online and i cant seem to get a good idea on then and from my limited attempts with them im not sure either. My friend was determined to try some and i put em in the oven for a couple jours with the door open on a temp some people recommended for red ones and he ended up shitting his pants and having tremors the whole time. He did mention some cool aspects to it but he overdosed on them no doubt and im curious if that muddled and positive aspects he would have gotten out of em. I have read some positive reviews with them but i need a method to go by.
Ive only dosed real low with them and didnt think they would be worthy to risk having a bad night...i have read some cool things about amanitas though and they grow everywhere soni might as well ask. Ive seen some panthers around here too but they scare the shit outta me haha, litterally?
Ive only dosed real low with them and didnt think they would be worthy to risk having a bad night...i have read some cool things about amanitas though and they grow everywhere soni might as well ask. Ive seen some panthers around here too but they scare the shit outta me haha, litterally?
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Sir Ron Pib
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No I really don't think it is; muscimol is a simple cyclopental with a couple of small do-dars sticking off - the Z drugs vary a bit but are way more complex with benzene rings and cocopops and others things strung on.
They don't act the same way either despite the GABA it binds differently and to 'rho' subtypes to benzo/barb/z type drugs
I really wish synthetic muscimol would become available - this along with bufotenine is an interesting drug get after a massive history (much larger than bufu) it's still shrouded in so much myth and misunderstanding and hardly used
Yup, it most definitely is not like the z drugs since those have an allosteric binding site, while Muscimol competes with GABA for GABA A and Rho binding sites. There are a few drugs available which bind directly to GABA A and Rho, but afaik they all bind to GABA Br's as well. Some are GABA prodrugs, some aren't. One is actually sold as a supplement in the USA.
Like Sir Ron Pib said, just look at e.g. Zolpidem's and Muscimol's structures. Muscimol has two polar groups at opposing ends (generally speaking, an O or OH group will always be polar, the same goes for the N), while Zolpidem is much larger and has two opposing apolar ends (phenyl rings are apolar aromats and they both have a methyl group, a single C, attached which is also apolar) on top of the polar end.
Looking at these criteria alone, the molecule size and how the charge is distributed, will give you a good idea whether a molecule might fit into the same binding pocket as another. Make no mistake though, there really aren't any globally valid rules. In this case, it is known the Z drugs are allosteric modulators of GABAr's opposed to Muscimol which binds isosterically, in the same spot as GABA itself, but not on GABA-B receptors.
Like Sir Ron Pib said, just look at e.g. Zolpidem's and Muscimol's structures. Muscimol has two polar groups at opposing ends (generally speaking, an O or OH group will always be polar, the same goes for the N), while Zolpidem is much larger and has two opposing apolar ends (phenyl rings are apolar aromats and they both have a methyl group, a single C, attached which is also apolar) on top of the polar end.
Looking at these criteria alone, the molecule size and how the charge is distributed, will give you a good idea whether a molecule might fit into the same binding pocket as another. Make no mistake though, there really aren't any globally valid rules. In this case, it is known the Z drugs are allosteric modulators of GABAr's opposed to Muscimol which binds isosterically, in the same spot as GABA itself, but not on GABA-B receptors.
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samm2
Bluelighter
amanita tincture is good,recipe from shroomery german guy---soak dried,powdered amanita in grain alcohol--i used potato vodka for one week,resoak again for another week---filter into bottle. Good winter tonic.
they go incredible well with dxm and shrooms i figured, i just took 600mg DXM the other day and right afterwards ate 34g of dried caps from eastern europe, waited 30 minutes, took 2 hits LSD and 15g shrooms and boom...
first i had an LSD trip and than i suddenly got put into space, i mean really, like pseudo hallucinations, real hallucinations, sedated, delirium, i had it all at once.
Best experience my life, the fly agarics of eastern and northern europe are way more powerful than shrooms, especially if you mix them, also it is impossible to feel anything, at least it was that day, i was like completely painless and sedated and high and dissoziated AND hallucinating at the same bloody time,... it was incredible.
first i had an LSD trip and than i suddenly got put into space, i mean really, like pseudo hallucinations, real hallucinations, sedated, delirium, i had it all at once.
Best experience my life, the fly agarics of eastern and northern europe are way more powerful than shrooms, especially if you mix them, also it is impossible to feel anything, at least it was that day, i was like completely painless and sedated and high and dissoziated AND hallucinating at the same bloody time,... it was incredible.
psykedenlitenment
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Incredible, huh? It may have been, however, you haven't got much hr in here. If anyone wishes to repeat this, mucho agua!!!!! Water!!!! L'eau!!!!! And probably substantially less fly agreric. Much less. Though I'm jaded as they've bitten me. Please just do LOTS of research; then do lots more. And tread carefully. Even when I took just one small cap followed by another small solitary cap an hour later for allergen testing, I was still sweating noticeably, and uncomfortably, without any physical exertion.
Please be safe with these.
Please be safe with these.
Wow that sounds fantastic. It's a shame none of my experiements had even the slightest effect, despite my unarguably very high doses.
methyldreams
Bluelighter
THE DANGEROUS POISONS MUSHROOM (THE AMINTA...THE MUSHROOM WITH A REDTOP WITH WHITE BUTTONS THAT EVERYONE SAID YOU SHOULD NOT EAT IT. OR THE TRIP IS HORRIBLE) looks like its from alice in wonderland.
I'm going to ingest for the 1st time very soon into the future, seemed quite interesting if you add i think was called serigel? not on my 1st time DW!
I'm going to ingest for the 1st time very soon into the future, seemed quite interesting if you add i think was called serigel? not on my 1st time DW!
It's a GABAa drug, like alcohol and benzos, so there's no problem.
samm2
Bluelighter
Latter I think the tincture was lacking something, too much gastro effects, too little gaba effects. From my research I decided putting tincture in hot water(just under boilingt) for 30minutes or so to decarboxylate the I think too much ibotenic acid to muscimol ratio.
It seemed to improve the the effects, more body high,sedate feelings. I'm using the Latvian by the way.
Goes good with red wine also,seems to strengthen the effects.
Nice.
Amanitas have always been something I want to try but I'm worried I'd take too much accidentally or have a bad reaction.
Have you ever taken them before?
Do people around here think Amanitas are relatively safe or do people think they could be dangerous if you take a little too much?
They've been on my list for a while but I haven't tried them yet. There's a lack of information on the decarboxylation process, which changes the ibotenic acid (which is neurotoxic) into muscimol (which is harmless but psychoactive, a GABAa agonist). Most people consider higher ibotenic acid content responsible for the negative effects people experience when they ingest amanita. I'd be quicker to try them if I had more information on how to fully convert all the ibotenic acid. Most sources specify dry heat, no temperature or time given.
They've been used as entheogens for a long time, though. I don't think they're very dangerous, I just like to be cautious when I see the word neurotoxin.
They've been used as entheogens for a long time, though. I don't think they're very dangerous, I just like to be cautious when I see the word neurotoxin.
Yeah, I don't know how to convert anything.
I know absolutely nothing about chemistry at all.
I'd just have to eat them whole however they came.
Can they just be eaten without altering them in any way or is that dangerous?