• MDMA &
    Empathogenic
    Drugs

    Welcome Guest!

The Big & Dandy 6-APB Thread (Part 1)

Status
Not open for further replies.
Ghostface said:
Back on topic!

How is the vomiting/need to crap issue for those who have dosed a second or third time?
Click to expand...

From memory,

Sample 1 - dash for a crap + bit of queasyness/dry retches (same with MDMA for me)

Sample 2 - dash for a crap + no queasyness to speak of.

Sample 3 - dash for a crap + moderate queasyness/dry retches, maybe one mouthful of vomit iirc.
 
Originally Posted by Ghostface
Back on topic!

How is the vomiting/need to crap issue for those who have dosed a second or third time?
Click to expand...

No vomiting or any similar issues whatsoever on the whole experience. i will say that at one point streams of sweat were poring off me and I was not exerting myself.

In a hot club, dancing this would probably not be a good look.
 
i wonder what the chances of sudden unexpected death, brain damage or damage to mental health could be. maybe this drug could cause a new type of condition previously unheard of or that it could trigger parkinsons or dementia years down the line. probly shouldnt think about it too much.
 
vecktor said:
No patents apart from the following:
European Patent EP1149085 2001
Japanese Patent JP2002535396 2002
United States Patent US7045545 2006
there are also Canadian Australian and World patents.

the US and European patents appear current and to have been maintained by Lilly.

6-APDB on the other hand is not patented nor patentable anywhere. 6-APDB is rather vomit inducing.

Maybe chindian labs would be wary of breaching the patent, given recent events in chindia regarding intellectual property violations
Click to expand...

Read the patent carefully - claim 1 of the patent covers 6-APDB but not 6-APB. That's because R and R1 as described by the claim are defined as hydrogen or other substitutions but no option is given for them to be absent. If you replace them both with hydrogen you get a substituted benzofuran - one of which is 6-APDB.
 
Lazyscience said:
i wonder what the chances of sudden unexpected death, brain damage or damage to mental health could be. maybe this drug could cause a new type of condition previously unheard of or that it could trigger parkinsons or dementia years down the line. probly shouldnt think about it too much.
Click to expand...

TBH you would'nt cross the road if you thought about it too much. I understand what you are saying but the fact is, we'll never know until it's too late.
 
bonbon said:
Read the patent carefully - claim 1 of the patent covers 6-APDB but not 6-APB. That's because R and R1 as described by the claim are defined as hydrogen or other substitutions but no option is given for them to be absent. If you replace them both with hydrogen you get a substituted benzofuran - one of which is 6-APDB.
Click to expand...
I read the patent very carefully
ABP is covered because it is example 3
APDB cannot be covered because it was described in published research pre-dating the patent, unless the case is made that using APDB as a 5HT2c agonist is a novel and unexpected use.

as a side note benzofuran contains 2 hydrogens in the furan ring, dihydrobenzofuran contains 4, it is called dihydrofuran because it is theoretically derived from benzofuran by adding 2 hydrogens to the furan double bond. I think that is why you are confused
 
Last edited:
Slam_London said:
Any educated guesses how 6apb will interact with sertraline/zoloft and aripiprazole/abilify?
Click to expand...

Quoted from 1st search result from Google :

"There are no direct physical dangers from mixing Zoloft and Ecstasy (MDMA). Zoloft (or to use its chemical name, Sertraline) is an SSRI (selective serotonin reuptake inhibitors), the same class of anti-depressants as Prozac (Flouxetine), Celexa (Citalopram Hydrobromide), Luvox (Fluvoxamine) and Paxil (Paroxetine). These chemicals will actually reduce or even completely eliminate the effects of Ecstasy when the two are taken together. Celexa, in particular is sometimes used to treat cocaine-dependency and may reduce cocaine effects and craving."

As the effects/compound of 6-APB are similar to MDMA, chances are that they will also react very similar to each other. This is again one of those questions that will only truly be answered with experience and time.
 
Last edited:
MrDoIt; said:
Quoted from 1st search result from Google :

"There are no direct physical dangers from mixing Zoloft and Ecstasy (MDMA). Zoloft (or to use its chemical name, Sertraline) is an SSRI (selective serotonin reuptake inhibitors), the same class of anti-depressants as Prozac (Flouxetine), Celexa (Citalopram Hydrobromide), Luvox (Fluvoxamine) and Paxil (Paroxetine). These chemicals will actually reduce or even completely eliminate the effects of Ecstasy when the two are taken together. Celexa, in particular is sometimes used to treat cocaine-dependency and may reduce cocaine effects and craving."
Click to expand...

Thank you. I expected as much. :-( Makes you wonder if 150 mg/pellet and a half, will do the trick? I guess time will tell. Any thoughts anyone on Abilify interaction?
 
uhm, ssri's and mdma or this is very dangerous, can you say serotonin syndrome. How the neurotoxicity look with this, or just toxicity? Compared to MDMA? Compared to mephedrone?
 
yourtman said:
uhm, ssri's and mdma or this is very dangerous, can you say serotonin syndrome. How the neurotoxicity look with this, or just toxicity? Compared to MDMA? Compared to mephedrone?
Click to expand...

Are you sure about that? You're thinking about interaction with MAOI medications surely?
 
Lazyscience said:
from my experience, taking mdma on an ssri completely stops the mdma from having any effect.
Click to expand...

For a full account of SSRI interactions see:

http://www.bluelight.ru/vb/showthread.php?t=108959

I'm currently in the final stages of tapering off Fluoxetine (Prozac) SSRI and should be clear of it and its long-lived metabolite Norfluoxetine by mid-July. I'll post a report on (a very, very cautious) overlapping with 6-APB if I get some before then.

As Shambles and others have suggested, 6-APB seems very close to the MD** drugs in its subjective effects, and this fact in combination with its close chemical structural similarity leads us to believe it'd be fairly close in its interactions with other drugs too. But it's uncharted waters ... :\
 
yourtman said:
uhm, ssri's and mdma or this is very dangerous, can you say serotonin syndrome.
Click to expand...
not an issue with ssri's. only with maoi's like grimmo already said. ssri's just bind to the site where mdma performs it's magic and stops it from working. i'd not expect 6-apb to be any different.
How the neurotoxicity look with this, or just toxicity? Compared to MDMA? Compared to mephedrone?
Click to expand...
most likely very similar to mdma/mda.
but there may be additional hepatotoxic or nephrotoxic effects. there are a few posts about that on page 3 (i think).
 
GlassCage said:
As Shambles and others have suggested, 6-APB seems very close to the MD** drugs in its subjective effects, and this fact in combination with its close chemical structural similarity leads us to believe it'd be fairly close in its interactions with other drugs too. But it's uncharted waters ... :\
Click to expand...

MrDoIt said:
As the effects/compound of 6-APB are similar to MDMA, chances are that they will also react very similar to each other. This is again one of those questions that will only truly be answered with experience and time.
Click to expand...


Whilst admittedly only an anecdote, it should caution against making any assumptions; there appears to be little cross tolerence between MDMA and 6-APB - a friend who just came back from a week of heavy partying in Ibzia (basically cained crystal MDMA for 6 of the 7 days), upon arrival back in the UK he sampled 100mg 6-APB that same day and got similar strength effects and duration as one would expect....
 
Skyline_GTR said:
Whilst admittedly only an anecdote, it should caution against making any assumptions; there appears to be little cross tolerence between MDMA and 6-APB - a friend who just came back from a week of heavy partying in Ibzia (basically cained crystal MDMA for 6 of the 7 days), upon arrival back in the UK he sampled 100mg 6-APB that same day and got similar strength effects and duration as one would expect....
Click to expand...

Agree with this - my first tipple was the morning after a fairly heavy night and it cut right through - it also felt new to me in some way.

Don't know if there'd be cross-tolerance with mda (or for that matter if there is between mdma and mda??) - but then it didn't much feel like when i've had mda pills in the past either - this may be placebo (or branding at work...)
 
^ Ha! "Woof Woof" was originally a joke from an EADD thread about where ridiculous alternate names nobody ever uses except papers come from. Not the first time some lazy journalist has skimmed BL and got it totally wrong. One of the supposed street names for meph was Mugabe according to one paper. Mugabe is an EADD regular not a drug. Although he loved his meph. They got that one wrong too - all the other papers are saying Woof Woof is MDAI. Silly people that they are :D

An aside on the cross-tolerance thing - I noticed that the effects of 2C-x taken the following day were greatly diminished. Not completely killed but barely noticeable at a dose that would normally have me in a very happy place. 6-APB was amazing in combo with 2C-B but there was a definite short-term cross-tolerance after my second time on 6-APB with no other drugs significantly involved. Pretty sure that's not the case with MDMA so I would agree with the above and urge caution in drawing any direct comparisons between them. They may be chemically related, they may feel quite similar subjectively, but they are not the same thing at all.
 
MrDoIt said:
As was pointed out to me back then, I was accused of being irresponsible as this is a HR site, and if threads are deleted then it could lead to someone not knowing what they should know about a substance and doing themselves harm. Thats fine, but the last thread on the subject of this RC was not a HR thread, and nor is this one. It is more like a PR campaign for this new "wonder drug", which is only serving to hype this drug up to everyone, including Government, and give a free advertising campaign to vendors who will be selling this RC.
Click to expand...

I was about to say, I forgot this thread was even in PD with all of this crap, seriously.

Mods can't complain if there are plenty of MODERATORS who have the ability to post how bomb this stuff is to get trashed on. Considering the context of these pellets I think that is reckless as hell to be honest, do you really think that makes the site look good? It sure isn't gonna help these pellet sales and bluelights level of perceived involvement on the surface.

The mods here are the kindest mods I know of anywhere on the internet, this thread just blows my mind. This isn't PD stuff, this is some street pushing crackhead shit.
 
i kinda agree that this isnt necessarily PD material. id love to try this shit tho.
could i start my own RC company guys? id carry what you guys all want, all the Moo Moo, Baaa! Baaa! and Quack Quack you can handle!
 
Status
Not open for further replies.
Top