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Tryptamines The Big & Dandy 5-MeO-MiPT Thread - Part 2

I used 5-MeO-DMT once over twenty years ago. It was entirely non-visual. Anti-visual, actually, as I lost touch with my sense of vision. (N,N-DMT is wildly visual.) I picked up some pre-web tryp foxy at the same time, but never took any, so I can't speak to it. Also got some 5-MeO-aMT at the same time, which I'm grateful to have avoided.

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Fun fact before I start: This is my 4th drug with "MiPT" in the name I tried. I did MiPT, 4-HO-MiPT and 4-AcO-MiPT before. I love all of them and now I love 5-MeO-MiPT as well.

I took a pill with a declared content of 10 mg of 5-MeO-MiPT.
Before I took it, the only thing I knew about this chem was that it was an empathogenic psychedelic. My expectations turned out to be accurate because the effects I experienced could be described as a psychedelic with a hint of empathogenicity. Overall, I am positively surprised by 5-MeO-MiPT because I expected something milder. At the beginning I experienced subtle, natural bodily euphoria manifesting as pleasant shivers, but there was also a hint of cognitive euphoria. These sensations started to fade, and in their place, the psychedelic aspect emerged. Clear visual changes such as rippling of images or color shifts occurred, and my way of thinking and perceiving reality also changed. The euphoria that appeared as the first effect of the substance would come back from time to time

The improved perception of music is also noteworthy. I could distinctly feel each layer and appreciate the beauty of the music more.

At the peak, I took a hit from a N2O cartridge – it nicely intensified the psychedelic effects for a moment. This was my first time with a psychedelic + N2O mix, but I will definitely revisit it because I see potential here.

The experience lasted for 4 hours, followed by just an afterglow. The body load was moderate. As expected with tryptamines – sometimes cold, sometimes short of breath, sometimes tight chest. It's bearable, and there's nothing to complain about. I may have felt some stimulation in the heart though...

In my opinion, it's closest to 2C-B among more popular drugs, but for my taste, 5-MeO-MiPT is a much more enjoyable and intriguing psychedelic than 2C-B. But I was never a fan of psychedelic phenyleths. HIGHLY RECOMMENDED. Soon, I might try 5-MeO-DiPT as well
 
That sounds lovely!

I'm surprised that 10mg oral only lasted 4hrs - maybe you metabolize it much faster than I do.
 
5-MeO-MiPT is a much more enjoyable and intriguing psychedelic than 2C-B.
I think this is something mostly true for you. I've turned a lot of people on to 2C-B and Moxy (5-MeO-MiPT). Generally, 2C-B is well tolerated and loved by most who've tried it whom I've given it to. I think Moxy is wonderful, and was surprised so many other people found it had too much body load for them and much preferred 2C-B in every RoA category. But, you know, different strokes & all that. It takes all types to make the world turn or something.

But I was never a fan of psychedelic phenyleths. HIGHLY RECOMMENDED. Soon, I might try 5-MeO-DiPT as well
I would be interested to hear your thoughts on Foxy. I tried that before I had had either 2C-B or Moxy. Foxy has more body load for me, and is a bit more aggressive in its eroticism. However, it's also a bit more nauseating during the come-up for yours truly, but also more of a psychedelic.
 
I think Moxy is wonderful, and was surprised so many other people found it had too much body load for them and much preferred 2C-B in every RoA category.
That's a surprise to me. I found the body load of 2C-B to be more intense than that of 5-MeO-MiPT. I guess it's different for everyone. Tryptamines used to give me a very harsh body load, but as I started to use them more frequently, the body load became less distinct. Eventually, the body load from tryptamines ceased to bother me altogether. However, it's still present with phenethylamines

I would be interested to hear your thoughts on Foxy. I tried that before I had had either 2C-B or Moxy. Foxy has more body load for me, and is a bit more aggressive in its eroticism. However, it's also a bit more nauseating during the come-up for yours truly, but also more of a psychedelic.
Thank you for sharing your insights. I'll definitely try 5-MeO-DiPT soon and let you know how it goes. What interests me most about 5-MeO-DiPT are the alleged auditory distortions, which somehow intrigue me. I've experienced a similar effect with N,N-DiPT before, and I loved it. I hope it will be present with 5-MeO-DiPT as well.
 
However, it's still present with phenethylamines
Keep using them and eventually the same thing that happen with tryptamines happens with PEAs.
What interests me most about 5-MeO-DiPT are the alleged auditory distortions, which somehow intrigue me. I've experienced a similar effect with N,N-DiPT before, and I loved it. I hope it will be present with 5-MeO-DiPT as well.
For me, I don't get much auditory hallucination effect unless I take a really big dose of either drug, DiPT being much more pronounced than 5-MeO-DiPT in its auditory effects. YMMV.
 
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How is this best stored? Ive stored 4-aco-dmt in freezer and last time did it , month ago, didnt know if it worked or not. Girlfriend said she didnt notice anything. Did use heavy cannabis and ate the entire time, so this may have been a factor. Used 4-aco-dmt maybe 4-5 times in past year so maybe time for a break , body may have become tolerant.

2022 did mal, mesacline related, a lot, maybe 10 x's , had some severe depression, not saying it was this, but am careful with mal or using anything too much. From expirience too much mdma and or empathogens have caused cognitive issues for @Innerpeace . Lsd they say can use more , and sub 4 typts, but common sense is not too often and you know your body more than anyone and if you think its best to take a break from a particular compound.

yeah rule of thumb is 10 mgs is more entacogenic, and higher is much more psychedelic. Have heard not good stories with higher dosing on this one .
 
How is this best stored? Ive stored 4-aco-dmt in freezer and last time did it , month ago, didnt know if it worked or not. Girlfriend said she didnt notice anything. Did use heavy cannabis and ate the entire time, so this may have been a factor. Used 4-aco-dmt maybe 4-5 times in past year so maybe time for a break , body may have become tolerant.

2022 did mal, mesacline related, a lot, maybe 10 x's , had some severe depression, not saying it was this, but am careful with mal or using anything too much. From expirience too much mdma and or empathogens have caused cognitive issues for @Innerpeace . Lsd they say can use more , and sub 4 typts, but common sense is not too often and you know your body more than anyone and if you think its best to take a break from a particular compound.

yeah rule of thumb is 10 mgs is more entacogenic, and higher is much more psychedelic. Have heard not good stories with higher dosing on this one .
Could condensation have been an issue? If you opened the bag/vial/whatever before it had reached room temperature then some moisture may have formed inside causing it to degrade.

It should be fine for years in the freezer. I've kept a 4-aco-dmt tincture in the freezer for over a year and it's been fine. I've also kept plain 4-aco-dmt fumarate in a glass amber vial at room temperature for over a year and that was fine too.
 
Yeah, it realistically shouldn't have degraded. Neither food nor tolerance should have been a factor. Sometimes psychedelics behave erratically. Weird, but hardly unheard of. It's not a serotonin releaser either, so I wouldn't extrapolate any risk of cognitive problems from it like from MDMA use. I use it frequently.
 
Yeah, it realistically shouldn't have degraded. Neither food nor tolerance should have been a factor. Sometimes psychedelics behave erratically. Weird, but hardly unheard of. It's not a serotonin releaser either, so I wouldn't extrapolate any risk of cognitive problems from it like from MDMA use. I use it frequently.
Same. The combination of it being in a fumarate salt form and it having that acetoxy molecule instead of the less stable hydroxy molecule like psilocin (4-HO-DMT) equates to it being quite stable with a long shelf-life. This and the lack of political red tape have led to it becoming popular among legitimate researchers. But it does degrade eventually, believe it or not…
 
So I had a very nice, but uncharacteristically long and rich experience with this a few weeks ago. No clue why. But I did have a single dropperful of yohimbe glycerine extract about 30min prior. Probably not a good idea. Anyway, that may or not have played a role. But yohimbe does contain some amount of raubasine, a potent cytochrome P450 2D6 inhibitor. And since both 5-MeO-DiPT and 5-MeO-DMT are both rapidly metabolized in vivo by CYP2D6, the same is probably true of 5-MeO-MiPT. Food for thought.
 
So then how do you feel about 5-MeO-DMT? Do you find it visual or not really compared to n,n-DMT? I have my own thoughts but I don't want to "lead the witness" as it were.

Also, do you have experience specifically with 5-MeO-DiPT as opposed to 5-MeO-MiPT? Circa 2000, Foxy Methoxy, 5-MeO-DiPT, was one of the very first RCs I ever messed with that I had not synthesized myself. Prior to this I had the opportunity to synthesize and try DMMDA-2 and DMMDMA-2 (they were interesting, but the latter was hardly active while the former was very strong).
DMMDA, Now that something that looks interesting to try.
 
DMMDA, Now that something that looks interesting to try.
DMMDA is made from Apiole oil I think, while DMMDA-2 is made from Indian Dill Seed Oil. Vac distilling this oil fills one's lab with the smell of dill pickles. To this day, whenever I smell pickles I can sorta 'flashback' to those days distilling Indian dill seed oil for the raw starting material to build DMMDA-2.

I think the Shulgin compound I'd like to try the most, at this point, would be MMDA, the "mind movies" psychedelic that allows one to review, in vivid detail, one's memories. It seems so useful, beneficial, and just plain cool. Maybe one day.

DMMDA-2 is a lot like MDA, but more psychedelic and grittier in terms of body load, though also it's fairly euphoric. So it's useful to be physically active on it so as to have something to channel some of that energy into.
 
Fun fact before I start: This is my 4th drug with "MiPT" in the name I tried. I did MiPT, 4-HO-MiPT and 4-AcO-MiPT before. I love all of them and now I love 5-MeO-MiPT as well.
Finally got some 5-meo-MiPT, I tried 4-ho-MiPT twice now and love that chemical so I'm stoked to try this. I have 5-MEO-DiPT in my stash for few years now, its still legal in Canada but you don't see it available that often. I am a little nervous to try it as DiPT version (AKA Foxy) seems to have more negative reports than MiPT (moxy). I want to try 4-aco-mipt and original MiPT too. There are so many yet to be banned tryptamines, I really feel like I should stock up and try them while i can
 
Finally got some 5-meo-MiPT, I tried 4-ho-MiPT twice now and love that chemical so I'm stoked to try this.
Be aware that the 5-substitution changes things quite a bit, adding some body load, and I find that both Foxy and Moxy have heavy erotic tones to them. Foxy is the first one I encountered. It has more physical load, more visuals and is slightly more psychedelic while Moxy has a more pronounced entactogenic quality, but they're very similar all the same. For me, Foxy is slightly more prone to a bit of initial nausea.

I have 5-MEO-DiPT in my stash for few years now, its still legal in Canada but you don't see it available that often. I am a little nervous to try it as DiPT version (AKA Foxy) seems to have more negative reports than MiPT (moxy).
I wouldn't read into that too much; may trip reports recount tales of recklessness. It is also worth mentioning that Foxy & Moxy can both be fickle. Sometimes 8 mg is a perfect dose. Other times it's mild for some people and intense for others. Either way, it's easily escapable with a benzo if you don't like where a trip is going, but I encourage this practice as only a last resort. It's better to take the good with the bad and to learn from the challenging trips, but it's sometimes impractical and it makes more sense to abort a trip if you really need to. Regardless, though I rarely do it, I find I feel much more comfortable having this option available to me while I trip. It's come in handy more than once in my life.

I want to try 4-aco-mipt and original MiPT too.
So 4-AcO-xT drugs mostly act as pro-drugs to their 4-HO-xT counterparts. Some feel there's a difference, but if there is, to me, it's not a super apparent or obvious difference, but that's my $0.02. I've had MiPT, MET, DiPT, DPT, and of course DMT among various tryptamines I've tasted over the years. DPT is cooler than I thought it would be; I had built up some fears in my head from reading trip reports on this compound, and while it was intense, it wasn't anything to fear. MET and MiPT reminded me of each other, and I still would like to experiment with injecting either or both drugs into substrate material used for growing psilocybin mushrooms/mycelium. Purportedly this will induce the shrooms into manufacturing the additional alkaloids, 4-HO-MET and its phosphate ester, 4-PO-MET.

There are so many yet to be banned tryptamines, I really feel like I should stock up and try them while i can
Probably a wise idea.
 
Finally got some 5-meo-MiPT, I tried 4-ho-MiPT twice now and love that chemical so I'm stoked to try this. There are so many yet to be banned tryptamines I really feel like I should stock up and try them while i can
Thanks for posting. 4-ho-mipt was first true psychedelic @Innerpeace did , was only one used for many years. which ones?

If you smoke this one, its highly recommend to smoke with non thc flower. Cannabis like cbd cannabis, also called cbd hemp flower sold at extremely limited stores (at least locally) can be pleasant. Its what @Innerpeace prefers with mdma or an empathogen,. IME its best to not mix with thc cannabis , first time or even few times , or even at all, with a new drug. Eventually, after expirience, it may depend what the compound is, willingness to expirement, like dissociatives , as weed may act as one, they seem to mix okay, but for most, ime, it may be safer and best to not mix thc with certain psychedelics, including mesacline family, mushroom family( synthetic include 4 and 5 subs) , lysergics.
 
Thanks for posting. 4-ho-mipt was first true psychedelic @Innerpeace did , was only one used for many years. which ones?
Why are you writing in the third person tense?

If you smoke this one, its highly recommend to smoke with non thc flower. Cannabis like cbd cannabis, also called cbd hemp flower sold at extremely limited stores (at least locally) can be pleasant. Its what @Innerpeace prefers with mdma or an empathogen,. IME its best to not mix with thc cannabis , first time or even few times , or even at all, with a new drug. Eventually, after expirience, it may depend what the compound is, willingness to expirement, like dissociatives , as weed may act as one, they seem to mix okay, but for most, ime, it may be safer and best to not mix thc with certain psychedelics, including mesacline family, mushroom family( synthetic include 4 and 5 subs) , lysergics.
It really depends on how the individual responds to cannabis and how often they smoke. I smoke frequently, and for me, cannabis & psychedelics go together like peanut butter & jelly, Coke & pizza. beer & peanuts, Calvin & Hobbes, Sonny & Cher, Heavy Metal & The Blues Note, Sly & The Family Stoned, fried chicken & waffles, El Gordo y La Flaca, drum & bass… You get the picture. Doesn't invalidate your warning, and different strokes for different folks and all that, but cannabis causes me no grief and never has.
 
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MET and MiPT reminded me of each other, and I still would like to experiment with injecting either or both drugs into substrate material used for growing psilocybin mushrooms/mycelium. Purportedly this will induce the shrooms into manufacturing the additional alkaloids, 4-HO-MET and its phosphate ester, 4-PO-MET.
Based on my understanding, the branched chain substitutions may not fit into the enzyme. I'm not sure if they are still active, but there used to be an analytical chemist at either DMT-Nexus or Shroomery who experimented with this a bunch. Maybe reading some publications by Dirk Hoffmeister (very friendly person!) et al would also be interesting.
 
Based on my understanding, the branched chain substitutions may not fit into the enzyme. I'm not sure if they are still active, but there used to be an analytical chemist at either DMT-Nexus or Shroomery who experimented with this a bunch. Maybe reading some publications by Dirk Hoffmeister (very friendly person!) et al would also be interesting.
Well the idea comes from TiHKAL, but I vaguely remember reading some other literature somewhere talking about how researchers injected mycelium substrate material with tryptamine and the variable group saw an increase in average alkaloidal content of as much as 25% compared to the control group grown in otherwise tryptamine-free substrate. I'll try to look it up if I have time later.

It also makes me wonder about various other compounds passing through the substrate material when laced with, for example, 5-MeO-MiPT. Would this result in some portion of 4-HO-5-MeO-MiPT being formed in the mushroom? If so, it might very well be a neurotoxin like 4,5-Dihydroxytryptamine.
 
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