So this friday a couple of friends of mine decided to go tripping again (I was not with them), after a break of over a year. They took a very high dose of the same batch (40 mg) of 4-HO-MET, which is basically psilocin with an ethyl and methyl group instead of two methyl (an added carbon atom, that is). Then all of a sudden one of them started to behave strange. Not that is isn't expected, but he went totally nuts; throwing books at the others, screaming and then eventually running out of the building.
When they went after him a while later (when they realized he was not coming back) they found that he had run out naked, stopped cars and jumped on them, completely shutting off the traffic. When the police and ambulance finally came, it took them >10 minutes to get him in the ambulance. The police had to physically force him in.
After a MRI-scan of his brain and heart at the hospital, and several experts called in from different hospitals to find out what went wrong, they concluded that he had suffered permanent brain and heart damage and that this could not be from trauma or anything else than the drug.
Now, everything I know about tryptamines says that this is impossible. If this is indeed caused by the drug, wouldn't there be more documented cases on this type of damage from the use of tryptamines (psilocin/psilocybin in particular)? Is it at all possible for serotonin agonists to cause that kind of damage?
I'll try to get in touch with the chief neurologist and get more data, but until then I figured I'd ask you guys. Since this is a drug that many of my friends use from time to time, and because this is a very unusual case, I'd like to shed some light on this.
UPDATE: Still haven't gotten in touch with any of the doctors. Hope to do so tomorrow though.