You will have to excuse me if this is a stupid question as I am currently half asleep but why bother making a solution that you intend to insufflate with acetylpsilocin? I thought liquid measurements were only used when handling chemicals active at sub miligram dosages such as the nbome series and to a lesser extent the DOxs. Does the liquid help absorbtion? If so I may have to give it a try. I love the decreased duration of nasally dosed 4-aco-dmt, come to think of it I have never actually tried orally dosing this chemical. If ones usual dose is 20-25mgs up the nose, what would be a good oral dose? I know the erowid chart says that there is only a 5mg difference between oral/nasal but it says the same about 4-ho-met which IME is untrue. Swallowing 30mgs of 4-ho seemed equivalent to sniffing 15mgs besides the obvious decrease in duration and a quicker come up.
Yes, better absorbtion, decreased nausea, increased potency, decreased duration, none of the nasty bitter taste, etc. When its dissolved in water, it absorbs better and is healther for your mucosa membranes, be it nasal or rectal.
And i would say weighing out single doses of stuff thats very active under 15mg, with a mg scale that doesnt cost an arm and a leg, is far from accurate. Psychadelics in particular, i want to be able to know the dose i took. With phens its easy as they last a long time in aqueaous solutions. Tryptamines not so much. Alcohol will decrease hydrolisis into psilocin and then fairly quick degredation to inactives at that point, but it still degrades much faster in solution. Even dry alcohols will cause degredation of 4-subs quicker than dry storage.
Its necessary with the superpotent ones, nbomes, dox, fly's, lsd, etc. But its a comfortable feeling when you absolutely know even if your scale drifts 5+mg, your dosage wont be off more than a fraction of a mg or so when doing batch liquid sollutions.
It would work, if you have friends that you shared it with, or could consume the 50mg or so to make the solution in a week or less, other than that it works fine if you dose out a single/or two doses and make a solution, at the expense of reduced accuracy. Just know it will degrade much faster in any solution iirc. Water is the worst, even if you freeze it and wrap it in foil. That helps, but its not enough time for me to go through the doses. Others may be able to do so.
IE, the only gripe i have with liquid solutions, delivered via mucosa membranes (one of the best ways to deliver a plethora of drugs imho, psychs or not), is that you need a large volume, and a significant # of doses prepared at once to get good accuracy when dosing. If you weigh out one dose at a time, and dissolve in and deliver that way, thats absolutely fine too, its just less accurate.