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Dissociatives The Big & Dandy 3-HO-PCP Thread

Okay, I got the suspicion the pressure sensation has been because of not the greatest care in spacing and ratio, because looking at the affinities Naltrexone really should sufficiently block the k-opioid receptor. I can spare a little more Naltrexone upon taking stock, so let's test that hypothesis, shall we. The day is stained with Naltrexone's noise profile anyway.

2/3rds Naltrexone now taken an hour prior, with the other 1/3rd half an hour prior. Roughly doubled the supplements as well, one half half an hour prior, other half at lift-off.

12mg 3-HO-PCP rectally. Some minor noise during come-up, no ear pressure. Noise profile not readily distinguishable from NAC's hiss, somewhat more tolerable than presumed serotonergic dissociatives like MXPr and MXiPr. I'd guess though partially blocked it's noisier than O-PCE, but I'd have to look into whether d-opioid reception is relevant to ear function or whether other mechanisms are at play. The effect definitely still is sedating and pleasurable, and I reckon a little kratom cousin won't hurt.


Edit to follow up that the ear was indeed perfectly protected during this trial. Which is to say I did indeed redose 12mg on the tea.

The behaviour though was unacceptable, the kratom-ish hole made a mess of the place with objects almost lost and local social structures disrespected. Opioid dissociatives are not for me in case I didn't already gathered that from the ear terror it has already given me before, almost ruining my sanity with this crap. o_O
 
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Pre-loading with Ginkgo Biloba seems to mitigate KOR-fuckery with this one, which is relevant to harm reduction.

It might mess with its dopiness though, I'm not sure.

The stacking formula could turn it into a less 'sheep' of an effect, protecting the ear yet allowing the dissociation?


Edit: It shouldn't really scrap the dopiness looking at the relevant receptor sites, but I do feel it does. Replication by another volunteer would be interesting. I like turning 3-HO-PCP into a more energizing dissociative, with less tinnitus tones generated.

ginkgo.png


Plenty of other good reasons apparently for supplementing with Ginkgo Biloba (containing Amentoflavone) on top!

From skimming the research papers, on the KOR front it's [Ki = 140 nM] for 3-HO-PCP, versus [Ke = 490 nM] (is Ke a thing?.. or just a typo in the paper?). So Ginkgo is the underdog (in affinity land: less is more), but it's within the same order of magnitude, so if dosed copiously an hour in advance it should indeed very much make a difference here. As my experience seems to verify.

It has a measurable effect on videogames as well, it's a really drippy of an effect, really weird. Interesting, but not really nice. Oh well, one way to use 3-HO-PCP and not being shot to the frikkin' moon.
 
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Vagabond696 said:
I just used 3hopcp to pull my name and my partners name from the satanic bible.

Fuck.
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Sounds about right - these pcp drugs can really make me think some crazy shit as well. 3-HO-PCP seems a bit peculiar in how 'sober' I still feel, yet I'm actually high as fuck thinking insane shit.

I won't take this drug again - I went through about 60mg in two days recently, and do not like the after effects. Very irritable, low feeling - grumpy as hell, and some weird muscle spasms.

I was taking a lot of St. John's Wort recently, so perhaps that's why I went through it so quickly.

Fun fact, St. John's wort is a great way to speed up elimination of dissociative from the body, if you're in a pinch or are trying to detox after a binge. Works for Kratom and some other drugs as well.

But yeah, no more 3-ho-pcp for me. Such a creeper, too - seems to take 2-3 hours to really kick in. So weird.
 
Yeah I had some fucking weird experiences with this compound. Haven't had any since that weird weekend and I don't plan on fucking with it again any time soon, haha. It's a great fun drug but definitely a mindfuck.
 
3-ho-pcp is a treacherous substance. I used it always Iv´d. The first times were great, very K-like. But soon I started loosing that feeling and always had a sense of being normal, not high, but I would fall for no reason and not put my hands to stop the fall. This happened to me several times until the last one 3 month ago, I hit my heaad hard in the front and back, blood everywhere, and couldnt understand what was happening, trying to wash the floor while still dripping red.
A couple of months later I started having the wors neck pain and muscle spasms, they thought it was a cervical rectification, but actually it whas a neck injury, kinda like a whiplash. I´m in the most pain now, gathering data so i can have a surgery and have a couple of discs removed and changed for metalic ones. I´ll never touch this chem again.
 
polidelaiko said:
3-ho-pcp is a treacherous substance. I used it always Iv´d. The first times were great, very K-like. But soon I started loosing that feeling and always had a sense of being normal, not high, but I would fall for no reason and not put my hands to stop the fall. This happened to me several times until the last one 3 month ago, I hit my heaad hard in the front and back, blood everywhere, and couldnt understand what was happening, trying to wash the floor while still dripping red.
A couple of months later I started having the wors neck pain and muscle spasms, they thought it was a cervical rectification, but actually it whas a neck injury, kinda like a whiplash. I´m in the most pain now, gathering data so i can have a surgery and have a couple of discs removed and changed for metalic ones. I´ll never touch this chem again.
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Aw damn that's awful... Really sorry to hear you're going through that, hopefully you get the medical help you need.
 
I have had only a few low dose experiences, as the older I get, the ligther I like my drugs.

Pretty lame, cold and brainfukery too, so not wanting to keep exploring it either. I would if it were the only disso available, but having at hand others, It doesnt make much sense
 
Just bumped 5+-mgs roughly 5-10mgs all my other sources I needed 20mgs+ for good experiences so either that stuff wasn't pure or this stuff is super fucking potent
 
What’s the dosing like with this one (oral) for a first time dose with no disso tolerance at the moment?
I’m looking for something in the ballpark of 10mg 3-meo-pce.
 
I got pretty intense effects nasal off 6-8mgs eyeballed I dosed like 30mgs over a night for 3 days and had one of the best times.
 
arrall said:
What’s the dosing like with this one (oral) for a first time dose with no disso tolerance at the moment?
I’m looking for something in the ballpark of 10mg 3-meo-pce.
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You'll look at a lot of things saying anything over 10mg is massive dose, and each mg makes a big difference.

I've done a lot of this stuff over the years, and found that it's more tricky than that. Thing is, it's such a clear headed dissociative, that it's hard to ever really feel like you've had 'enough' or are 'high' as the illusion of sobriety is strong.

I would suggest starting with 5mg, and redosing 5mg every hour or two after that.
 
cryptix420 said:
You'll look at a lot of things saying anything over 10mg is massive dose, and each mg makes a big difference.

I've done a lot of this stuff over the years, and found that it's more tricky than that. Thing is, it's such a clear headed dissociative, that it's hard to ever really feel like you've had 'enough' or are 'high' as the illusion of sobriety is strong.

I would suggest starting with 5mg, and redosing 5mg every hour or two after that.
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I melted into a space depot and didn't know the difference between my body and my GFS and could barely tell what I was seeing in full light because the hallucinations were so intense and full it's a blur basically now
 
VidaliaOnions said:
I melted into a space depot and didn't know the difference between my body and my GFS and could barely tell what I was seeing in full light because the hallucinations were so intense and full it's a blur basically now
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Sounds like a hell of a trip 😃

Love your user name by the way, those are one of my favorite vegetables by a longshot. No other onion even comes close to their majesty, so sweet and delicious. You have excellent taste in food my friend!!!
 
arrall said:
What’s the dosing like with this one (oral) for a first time dose with no disso tolerance at the moment?
I’m looking for something in the ballpark of 10mg 3-meo-pce.
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It is a bit more potent than 3-MeO-PCE but not by much. I imagine 8-10mg 3-HO-PCP would feel about equal to 10mg 3-MeO-PCE.

Orally I start to feel first alerts around 30 minutes that slowly build until about the 90 minute mark when it starts entering the peak. I'd usually insufflate it because I'm impatient and 3-HO-PCP hits the sinuses like air, but I'm trying to be better about sticking with oral dosing
 
VidaliaOnions said:
Yah a good starting dose is 8mgs and did it taste like wintergreen tobacco chew with the initial bumps and then it turned into a chemically drip? On this 3 ho pcp.
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Can relate to the wintergreen. 3-HO-PCP, at least the recent batches I have gotten have a unique smell when I snort it. A fairly pleasant smell imo
 
Exactly a few dissociatives have all bad a unique minty winter flavor but plenty have just tasted like straight chemical haha but it's weird wonder what causes dissociates to tend to that type of flavor
 
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