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Phenethylamines The Big & Dandy 2C-I Thread - Take Two

Yeah, exactly. I'm not claiming to grasp this situation perfectly either, I'm just saying it makes sense to me, since Xorkoth pointed out that the idea of patenting methylone as an antidepressant seems odd now, that it may have seemed a lot more promising back then with SRAs being much less understood and SSRIs still being seen as the hot new thing in depression. I personally think taking an MDMA-like drug every day as a depression prescription seems like a terrible idea now too, but back then, I could see why it could seem like it had promise.

The whole "chemical imbalance" thing definitely irks me. But I'm one of those people who thinks that what we call mental disorder is often times really just more like having a different kind of brain or even just being in a different brain state. Like maybe some of the things we think of as insanity actually made more sense down our evolutionary line before we became too smart and started forcing ourselves to only reinforce the things we could make the most sense of, which isn't necessarily a bad thing, but maybe sucks for the people who don't work in that particular way. I don't know, I think about this stuff a lot though.
 
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Nichols was my hero more than Shulgin after awhile, back when I was more serious about wanting to pursue neurochemistry. Going to work at his lab at Purdue was my pipe dream.
Ditto on the pipe dream of working for Nichols. Once I earned my PhD in biochemistry I was researching potential postdocs and...yeah, that was my pipe dream. Having a PhD on the topic of yeast genetics doesn't quite qualify me to study neurochemistry. Plus, I was a less than stellar grad student, so I assumed (probably rightfully) that I didn't stand a chance. Never tried to apply or even contacted Nichols, which after typing this out sounds like more of a lost opportunity than I think it really was.

Did you pursue another topic in science?
 
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Just was able to procure 250mg of 2c-I. It’s been over a decade since ive tried one of my favorite 2c compounds. I already have 2c-e I recently got last week, but am saving that for a day where I’m in a space for a more serious experience. 2c-I is more forgiving and recreational
 
Though I don’t think I recall ever having a bad trip on 2ce even when taken up to 30mg (except the time I recklessly snorted 50mg of 5-meo-dmt at the peak of 30mg 2ce). Some mild difficult parts but it was relatively easy to manage compared to something like a very high does of shrooms or lsd.
 
Bon voyage! I had hoped to recover my pre-operation Web Tryp stash from far away earlier this year, but it didn't happen. I've still never tried it. I hope you enjoy it!
 
I guess Indopan (aMT) was around as an antidepressant in the 60s. I don't recall when it was discontinued.



Pretty sure it got recalled because of people getting seratonin syndrome and dying. Which may have been from them mixing it with other psychiatric drugs and not realizing the disaster potential there. aMT is one of the drugs you have to take very seriously cuz it can knock you off. When i use it i honestly try not to have any drugs in my system at all.

The last time i took it i broke that rule and had FXE the day before and it gave me this wicked headache for days. But yeah i remember reading about studies from back then where deaths happened, but also i believe it abuse/lovely potential got realised and maybe they didnt want a bunch of housewives rolling?
 
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Pretty sure it got recalled because of people getting seratonin syndrome and dying. Which may have been from them mixing it with other psychiatric drugs and not releasing the disaster potential there. aMT is one of the drugs you have to take very seriously cuz it can knock you off. When i use it i honestly try not to have any drugs in my system at all.

The last time i took it i broke that rule and had FXE the day before and it gave me this wicked headache for days. But yeah i remember reading about studies from back then where deaths happened, but also i believe it abuse/lovely potential got realised and maybe they didnt want a bunch of housewives rolling?
Damn I’ve only had AMT a few times a long time ago. It was an awesome compound though I had a little nausea coming up. It’s akin to a mix of mdxx and psychs and last quite a bit. Best thing is I didn’t feel depleted the following day like I tend to do with other substances. Def would like to get reacquainted with this lil guy
 
Damn I’ve only had AMT a few times a long time ago. It was an awesome compound though I had a little nausea coming up. It’s akin to a mix of mdxx and psychs and last quite a bit. Best thing is I didn’t feel depleted the following day like I tend to do with other substances. Def would like to get reacquainted with this lil guy

Ohh its such a good drug my favorite empathogen most likely, mainly cuz of the duration and lack of a comedown like you speak of. Its not as in your face with the rolling as say MDMA is, has more of a wave effect that just lasts forever.

Its excellent and having sex on it is wonderful, it turns me into a damn porn star and i will just go again and again all nite. I have like about a gram tucked away but im not gonna use it often and will try to hold onto it for years. Concerning the nausea the best way to avoid it is plugging, but i know thats not an option for you now and me either.

So im gonna try and dose lower around 20mgs and use ginger at the same time orally and see how i fair. In the past i would plug 60mgs at a time and it was just a breathtaking experience, i did it quite often at one point at least once a month.
 
Ohh its such a good drug my favorite empathogen most likely, mainly cuz of the duration and lack of a comedown like you speak of. Its not as in your face with the rolling as say MDMA is, has more of a wave effect that just lasts forever.

Its excellent and having sex on it is wonderful, it turns me into a damn porn star and i will just go again and again all nite. I have like about a gram tucked away but im not gonna use it often and will try to hold onto it for years. Concerning the nausea the best way to avoid it is plugging, but i know thats not an option for you now and me either.

So im gonna try and dose lower around 20mgs and use ginger at the same time orally and see how i fair. In the past i would plug 60mgs at a time and it was just a breathtaking experience, i did it quite often at one point at least once a month.
You Lucky fuck. Sharing is caring my friend
 
it’s been over 10 years since I’ve used 2c-I. Now from what I recall my batches were always white in appearance. This batch has a rather tannish hue to it. I’m guessing the chemists didn’t bother with further refinement methods. Not sure when I’ll be able to trip, but ima def do allergy test this weekend. Looks like 25i-nbome that I’ve ordered in the past so just sketches me out, but the 2c-I did came from a reputable source and I know hcl compounds aren’t always perfectly white. Still good to proceed with caution.
 
My material is not new, but my body is about a 1.5 decade older. I think I'm going to start titrating this one soon. I believe 2C-I was the most stimulating of the psychedelics I've tried. I hope my body can still tolerate it.

Since my return to psychedelics, I've found 2C-E to be more stimulating than I recall it being, and this may be due to changes in my physiology. Since 2C-I was a lot less mentally active for me, perhaps my experiments with it will give me a better sense what's going on. And anyway, despite the fact 2C-I kind of fell out of favor for me it was still a lot of fun and was among the best for casual environments. It pretty much made MDA/MDMA obsolete for me as it offered a much better high and much nicer after-effects.

My titration schedule probably looks like: 0.5 mg, 1.5 mg, 3 mg, 6 mg, and then 10-12 mg followed by maybe 16 mg, which in the past was a comfortable medium dose for me. This will take me at least a few weeks to complete as I will be traveling for some of the time.

To @higherconciousness: I hope your material turns out to be legit and you have a good time with it.
 
I still have some 2C-I from 2011. Sealed in safe environment. Still as potent as the day I got it. I use it sparingly since its nearly impossible to find. But it is my favorite 2C next to 2C-T-7.. and 2C-B of course!
 
I took 1.5 mg today an had a definite (+) that lasted ~9 hours. I actually think this was stronger than 1.5 mg of 2C-E for me, but the latter may have a steeper response curve. I was expecting/hoping for some stimulation to cut through the tired, foggy, post-migraine state I was in (despite getting plenty of sleep), but no such luck. The effect was clearly psychedelic, principally somatic, and it amplified the body jangles which were already there. I felt least bad while lying down and closing my eyes, and this would have probably been the case if I'd staid sober too.

Two days before, I'd had a (+/-) with 0.5 mg but I'm fairly sure I felt it. That experience was quite pleasant, unlike this one.

Anyway, in my earlier years, I always considered 2C-I to be very stimulating and felt the stimulation to be a significant effect alongside the psychedelic effect, but perhaps that was merely a consequence of suggestibility. I had also assumed that 2C-I had a strong "positive push"---that it would be hard to have a "bum trip" on it---but no such positive push was there today. Maybe this kind of thing will develop at higher doses? I will try to find out. Though, I will also try to avoid any more experiments when my body is not feeling so good.

BTW, I use a fair amount of cannabis on these low dose trials to "bring out" more effects.
 
I put off the 3 mg trial until today so I could observe my body and give my mind more time to process the last experience. Here is my mini report:

I sipped the dose over a 5 minute period. This time the onset was very smooth with just some tummy/gut awareness. No rushes. At T+1:15 I was confident I didn't need to be near the toilet and went outside to rake leaves with my wife. The chore felt pleasant, easy, and satisfying. I did not feel stimulated, but I didn't feel any fatigue either. I did seem to sweat about 3 times as much as might be normal, or maybe I was working harder than it felt like. In about half-an-hour, we filled up all of our lawn bags and decided to walk to the hardware store to buy more. They were sold out, so we finished the area with a plastic bag and then set out for a pleasant walk. Wife (who only had cannabis) seemed to have a bit of a contact high and remarked about the considerable time dilation. Visually, I noticed the perspective effect of pupil dilation and a slight enhancement of details but nothing dramatic. The sunlight also seemed a bit cooler in color temperature than normal, but I noticed that yesterday (without psychedelic) as well.

When we got home, it was still only T+3.5, and I put on some Infected Mushroom / Classical Mushroom, which I followed with some other random psytrance. The music euphoria was excellent, and I got a couple hours of good dancing in. Around T+4.5 I prepared and ate my dinner while actively dancing. I only ate half the portion though and saved the other half for after my shower, which was at T+5. When I got out of the shower, I was feeling incredibly blissful, and after I finished dinner, we watched a couple episodes of "Babylon 5"---a series I'm viewing for the first time. (IMO, this show is really excellent and seems very timely relative to current events in the real world.)

Overall I had a wonderful time today and experienced bliss on a level that I don't think I've felt since my early trips > 11 years ago. I had stimulation no different from other psychedelics. The urge to move to the music was there as was the energy when I did so, but I did not feel pushed or overdriven at all. Granted, the effects weren't nearly as strong as my recent 8 mg 2C-E experience in which I d felt rather over-stimulated in the late plateau. This is a big reason for me choosing to explore 2C-I again. I wanted to feel the "2C-stimulation" with minimal mind-fuck, so that I could better understand what I felt on the 2C-E. My reasoning is that if the stimulation from 2C-I bothers me, then the 2C-E "over-stimulation" was probably a drug effect that I'm more sensitive to. OTOH, if I don't have this problem with 2C-I, then the "over-stimulation" of the 2C-E may have been more of a psychological effect---a bodily manifestation of some kind of thought-form that needed processing. Of course, this thought-form could also re-emerge on 2C-I as well, but I assume I'm less likely to encounter it on the I than the E.

Perhaps it's too soon to judge, given that I only had 3 mg of 2C-I, and I got a surprising amount of sparkle out of that 3 mg! I do recall when I was young, after my first (mild) trip with 2C-I (10 mg? don't recall), I tried taking 3 mg before work as a stimulant. I was waiting tables, and when it hit me, I felt really uncomfortable and then I felt like I was doing everything twice as fast---way too fast for a "normal stimulated day". Also as the effects hit, I developed an ocular migraine, which was very disturbing. Many migraine sufferers experience an *aura*, a kind of altered state before the headache sets in characterized by among other things visual distortions. These visual distortions aren't trippy though. They are more like playing a dirty Nintendo (NES) cartridge (sorry kids). It's like having areas of stuck pixels (which can be static or moire-like patterns) that completely obscure the vision of parts of the eyes. They also pulse with the heart beat, which is extra creepy. Thankfully the aura only lasted an hour or so, and when I got home, I felt fine. An Internet search helped me understand what I'd experienced. I've had a couple other ocular migraines since without taking anything, so I have no idea if the 2C-I triggered it or if it was just an obnoxious coincidence. The experience did leave me with the impression that 2C-I was hyper-stimulatiing in a way that might actually be worse in lower doses, and given my difficult 1.5 mg experience earlier this week, I was quite nervous for today. Thankfully, today was not a repeat of either of those unpleasant experiences. I now feel reasonably comfortable moving to 6 mg some days from now!

One thing that is becoming absolutely clear to me from these low dose expeditions is that even a (+) experience is still psychedelic, and as Sasha said, there are no casual experiments. If I take 3 or even 1.5 mg 2C-I and my set or setting are bad, then my experience will likely be negative too. It's unlikely to be a train wreck, like too high a dose in a bad setting could be, but it still matters a lot to how the trip goes. Hence, it's best to prepare for these low dose experiences almost as much as I would for high dose experiences. Furthermore, even 2-3 days between these kinds of low doses is fine for tolerance, my mind might still need longer for post-processing.
 
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