I’ve tried mixing 4-HO-MET with 2C-B a few times now and I typically find that the 4-HO completely overpowers the 2C-B. I just go from tripping on 2C-B to tripping on 4-HO-MET with no notable synergy.I tried 4-AcO-MET on top of 2C-D once, and to my surprise it didn't seem to blend well. Could definitely have been the idiosyncrasy of that particular trip though, or the ratios I used, It's hard to judge on one go, but it has made me hesitant to try similar combos hencewith.