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The Big & Dandy 25I-NBOMe Thread

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Typewritermonkey said:
So I dissolved 500mg of 25i into 250mL of 99% EtOH to get a concentration of 2000ug/1ml. ...
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in the spirit of harm reduction, ive gotta ask you this: you did weigh out the 500mg on a mg scale, eh? i noticed just a couple days ago you said it would be a couple weeks before you had your mg scale..

the only reason i ask is my roomies and i once ordered 100mg samples of DOI, and i made a solution with mine and dosed out of it based on that number. over 30hrs after consuming what i thought was 1mg, i realized the sample they gave me may have weighed more. my roomates and i had gotten 3 100mg samples total, and upon weighing one that was untouched, it was somewhere around 170mg..

my point being sometimes theythrow in extra, or maybe are just being lazy and approximating. never trust the vendors measurements. they are often incorrect. just lookin out for ya! <3
 
plusfourpirate said:
in the spirit of harm reduction, ive gotta ask you this: you did weigh out the 500mg on a mg scale, eh? i noticed just a couple days ago you said it would be a couple weeks before you had your mg scale..

the only reason i ask is my roomies and i once ordered 100mg samples of DOI, and i made a solution with mine and dosed out of it based on that number. over 30hrs after consuming what i thought was 1mg, i realized the sample they gave me may have weighed more. my roomates and i had gotten 3 100mg samples total, and upon weighing one that was untouched, it was somewhere around 170mg..

my point being sometimes theythrow in extra, or maybe are just being lazy and approximating. never trust the vendors measurements. they are often incorrect. just lookin out for ya! <3
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Yes, I used a lab grade mg scale capable of weighing out just to the .0000g, it has a wind-proof caseing and is bolted to the ground. Regards to this, I weighed my material, and it weighed to 580mg. I presume this is because it is the HCL, and the HCL represents 16-25% of the weight of the compound (making it ~500mg 25i, ~80mg HCL). It dissolved in water too.

Even if I was wrong, and they gave me 580mg of material, my math makes it out to be that their could be a maximum concentration of ~235ug per .1ml, giving each .1ml a range of ~200-235ug which I deemed appropriate for error, as some make their solutions at 250ug.


Thanks for watching out though! It really means a lot especially with a compound like this. Thankfully I'm lucky enough to have access to a university lab for my research. It was a seriously beautiful day for me today, deeply resonant with the heart and a bit of a mental/spiritual awakening. I am excited for further trials.


On another note, with physical maladies that result from this, what is the usual ceiling dose for this? I'd give it 2mg if sublingual or bucally, 750ug if insuffulated, but would like to know everyone else's opinions.
 
The HCl salt is 8% of the total mass, meaning you had an equivalent of 533mg of freebase.

That said, I think most people have the salt, and as such, have been reporting 0.5mg as 0.5mg of salt.
 
Thank you Transform.

So since you said complexing isn't necessary for the salt, I still acquired some beta cyclodextrin before I even knew if I was getting the freebase v. HCL. Since it just got here, would it be pointless to complex my already made solution with it to increase absorption? Or is the HCL fine on it's own like you said.

Thanks again, this thread is the only real resource for information on this compound IMO.
 
Nope, no need to bother if you have the salt.

Complexing serves only to make the freebase water soluble for absorption, and the salt is already soluble.
 
I have now read the entire thread and I will be looking to procure some of this.

However, I have a few questions (or rather would like some clarification and confirmation that I did not misunderstood).

HPBCD is not needed if the form is soluble in water, correct? But HPBCD does increase bioavailability even if the form is soluble in water, correct? (at least there were claims to this in the thread).

There have been mentions of magnetic stirrers in the thread. What are the advantages of using a magnetic stirrer compared to stirring by hand? There have also been mentions of micropipettes, and I see micropipettes of 500ul can be acquired quite cheaply on e-bay. Would this be worthwhile investment? I read micropipettes need to be calibrated - how do you go about doing this?


The following is my own idea: Since buccal administration is a good ROA, what about adding drops to portion bags of nicotine-free snus?

Pic: http://www.getsnus.com/images/prillor.jpg
Wiki article: http://en.wikipedia.org/wiki/Snus

I have looked at what various brands of nicotine-free snus contains. One brand, for example, is made of durum wheat, ginseng and various spices (not specified). Could it mix bad with 25i-NBOMe?

Any other reason why this would not be a good idea? Thanks in advance.
 
Does anyone think Gingko biloba would be wise to be used to counteract the vasoconstriction pretty much every user feels? Any other ideas to help other then cannabis, oranges and moving about?
 
Not necessarily, but it is most likely. Ask them.


Isidor, don't bother complexing, just dissolve in vinegar or dilute HCl and use that.

I like the nicotine-free snus idea, no reason I can think of that it wouldn't work, except perhaps excessive swallowing.
 
is it OK to use 0,9% NaCl instead of pure distilled water on the solution? Will it react with 25I-NBOMe?
 
There's 5 ml vials available that supposedly contains 50mg 25i-NBOMe and are supposed to be "heavily complexed". Going with the ideal ratio mentioned here of a 9:1 ratio HPBCD:25i-NBOMe that would mean 450mg HPBCD. Is that amount of HPBCD soluble in 5ml?
 
Any input on combining 25i-NBOMe with Mushrooms?

I was considering taking a 550ug tab buccally, and about an hour later eat 1-1.7 grams of shrooms. Never combined psychedelics much, but this seeems like it may be nice.

Anyone?
 
freedstar said:
Any input on combining 25i-NBOMe with Mushrooms?

I was considering taking a 550ug tab buccally, and about an hour later eat 1-1.7 grams of shrooms. Never combined psychedelics much, but this seeems like it may be nice.

Anyone?
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There have been reports of 25i taken with LSD or mescaline, and both people said they enjoyed it immensely. I can't speak for mushrooms, but the combo of L and 25i was beautiful.


The dosages sound right, but try 25i on it's own to know your reaction to it first, and keep a sitter around.

Happy trails.
 
So... Tonight I put 5mg of 25i-nbome hcl into 2ml of Tobacco flavored e liquid

about 5 hits off of my e cigarette and I was at a +++

I feel like a mad genius. I just created a monster. I'm sure this has been thought of or probably even done before, but I haven't heard of it anywhere so I figured i'd share... nbome salts can be put into e liquid(Propylene Glycol) and vaporized through the atomizer of an e cigarette, to excellent effect.

probably going to stick to this roa for my personal experiences.

anyone else tried this??
 
Interesting, be careful though. I'd measure a dose from the liquid with a 1mL syringe and drip it on the wick, rather than fill a cartridge with it (if that's what you did). Then when you're done or smoked it all, wash the atomiser well. I don't know if you could get any buildup somehow and later get an unexpected dose, but better to be safe and wash it every time.
 
ntat said:
So... Tonight I put 5mg of 25i-nbome hcl into 2ml of Tobacco flavored e liquid

about 5 hits off of my e cigarette and I was at a +++

I feel like a mad genius. I just created a monster. I'm sure this has been thought of or probably even done before, but I haven't heard of it anywhere so I figured i'd share... nbome salts can be put into e liquid(Propylene Glycol) and vaporized through the atomizer of an e cigarette, to excellent effect.

probably going to stick to this roa for my personal experiences.

anyone else tried this??
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That sounds really awesome, although unfortunately somewhat wasteful. I've read of people easily getting 5 +++ experiences out of that amount. Was there still more after you took the 5 pulls? How long were you under the influence?
 
well 5 pulls on it comes out to about 1 mg i believe... if my math is correct anyway, this was really just a impromptu experiement

lasted about 4 hours... i vaped more after about 2 hours only to have the effects kind of hit a plateau and only extended the experience another hour or so... this was due to the rapid tolerance you get from using nbomes, i'm sure if i had hit it more at the beginning it would have had much more increased effects.

i def think it's less wasteful than vaping it like i was previously off of tin foil with a cup to catch the vapors... a lot of the vape escaped the cup that way

I also have a tolerance from using this shit for the past few days... being able to have a 3 hour experience after work and still get to bed and wake up at a decent time has been entirely too fucking convenient for me... not good for it to be that easy. but the tolerance def makes abusing it with any kind of negative consequences nearly impossible because after about the 3rd day or so you become practically immune to it. gonna take a week break and try it next weekend with zero tolerance and see how strong it is out of the e cig then :)
 
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